Granulomatosis With Polyangiitis

Also known as: Granulomatosis, Wegener's / Wegeners Granulomatosis / Wegener's Granulomatosis / Wegener Granulomatosis (WG) / Wegener’s Granulomatosis / Wegener Granulomatosis / With Polyangiitis, Granulomatosis / Pulseless disease / Granulomatous polyangiitis / Wegener's granulomatosis NOS

DrugDrug NameDrug Description
DB00531CyclophosphamidePrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
DB00073RituximabRituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences [A40017], [FDA label]. It was originally approved by the U.S. FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label]. On November 28, 2018, the US FDA approved _Truxima_, the first biosimilar to Rituxan (Rituximab) [L4808].
DrugDrug NamePhaseStatusCount
DB12880Interleukin-101Completed1
DB00688Mycophenolate mofetil1Completed1
DB00073Rituximab1Completed1
DB01281Abatacept1 / 2Completed1
DB00993Azathioprine2Completed1
DB08879Belimumab2Recruiting1
DB12330Blisibimod2Withdrawn1
DB00531Cyclophosphamide2Completed2
DB00531Cyclophosphamide2Unknown Status1
DB00111Daclizumab2Completed1
DB00005Etanercept2Completed1
DB12692Gusperimus2Completed1
DB00065Infliximab2Completed1
DB00563Methotrexate2Completed1
DB00563Methotrexate2Unknown Status1
DB00959Methylprednisolone2Completed1
DB00688Mycophenolate mofetil2Completed2
DB00704Naltrexone2Recruiting1
DB00860Prednisolone2Completed1
DB00635Prednisone2Completed1
DB00073Rituximab2Completed1
DB00993Azathioprine2 / 3Completed1
DB00531Cyclophosphamide2 / 3Completed2
DB00005Etanercept2 / 3Completed1
DB00959Methylprednisolone2 / 3Completed1
DB00635Prednisone2 / 3Completed1
DB00073Rituximab2 / 3Completed1
DB01281Abatacept3Recruiting1
DB00993Azathioprine3Active Not Recruiting1
DB00993Azathioprine3Completed1
DB00531Cyclophosphamide3Unknown Status1
DB12692Gusperimus3Terminated1
DB00688Mycophenolate mofetil3Unknown Status1
DB00635Prednisone3Recruiting2
DB00073Rituximab3Active Not Recruiting1
DB00073Rituximab3Completed2
DB00087Alemtuzumab4Unknown Status1
DB00860Prednisolone4Recruiting1
DB00635Prednisone4Completed1
DB00073Rituximab4Completed1
DB00073Rituximab4Recruiting1
DB00091CiclosporinNot AvailableUnknown Status1
DB00531CyclophosphamideNot AvailableUnknown Status1
DB00099FilgrastimNot AvailableUnknown Status1
DB00065InfliximabNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableUnknown Status1
DB00635PrednisoneNot AvailableUnknown Status1
DB00073RituximabNot AvailableCompleted2
DB10805Yellow Fever VaccineNot AvailableCompleted1