Idiopathic Short Stature (ISS)
Also known as: ISS- Idiopathic Short Stature / Short Stature, Idiopathic / Idiopathic Short Stature / Idiopathic short stature (disorder) / Short stature (child) / Short stature / Stature short / Short stature disorder (disorder) / Small stature
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB00052 | Somatotropin | A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB00052 | Somatotropin | Growth hormone receptor | target |
| DB00052 | Somatotropin | Prolactin receptor | target |
| DB00052 | Somatotropin | Cytochrome P450 1A2 | enzyme |
| DB00052 | Somatotropin | Cytochrome P450 2C19 | enzyme |
| DB00052 | Somatotropin | P-glycoprotein 1 | transporter |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB00052 | Somatotropin | 1 | Completed | 1 |
| DB00052 | Somatotropin | 2 | Completed | 2 |
| DB01217 | Anastrozole | 3 | Completed | 1 |
| DB01006 | Letrozole | 3 | Completed | 1 |
| DB00007 | Leuprolide | 3 | Completed | 1 |
| DB00052 | Somatotropin | 3 | Completed | 7 |
| DB00052 | Somatotropin | 4 | Active Not Recruiting | 1 |
| DB00052 | Somatotropin | 4 | Completed | 3 |
| DB00052 | Somatotropin | 4 | Withdrawn | 1 |
| DB06825 | Triptorelin | 4 | Active Not Recruiting | 1 |
| DB00052 | Somatotropin | Not Available | Active Not Recruiting | 1 |
| DB00052 | Somatotropin | Not Available | Completed | 1 |
| DB00052 | Somatotropin | Not Available | Terminated | 1 |