Erectile Dysfunction (ED)

Also known as: Impotency in men / Sexual impotency / Male impotence / Male Erectile Disorder / Impotence / Erectile Dysfunction / Impotence NOS / Erectile dysfunction NOS / Impotent / Erectile disturbance / Erection failure

DrugDrug NameDrug Description
DB00770AlprostadilA medication used to treat erectile dysfunction.
DB06237AvanafilA phosphodiesterase 5 (PDE5) inhibitor used to treat erectile dysfunction.
DB00203SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DB00820TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
DB00862VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
DrugDrug NameTargetType
DB00770AlprostadilProstaglandin E2 receptor EP2 subtypetarget
DB00770AlprostadilProstaglandin E2 receptor EP1 subtypetarget
DB00770AlprostadilMultidrug resistance-associated protein 5transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2B1transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 3A1transporter
DB00770AlprostadilMultidrug resistance-associated protein 4transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2A1transporter
DB00770AlprostadilProstaglandin D2 receptor 2target
DB00770AlprostadilSolute carrier family 22 member 6transporter
DB06237AvanafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB06237AvanafilCytochrome P450 3A4enzyme
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilP-glycoprotein 1transporter
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB00820TadalafilCytochrome P450 3A5enzyme
DB00862VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00862VardenafilCytochrome P450 3A4enzyme
DB00862VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilCytochrome P450 3A5enzyme
DB00862VardenafilP-glycoprotein 1transporter
DrugDrug NamePhaseStatusCount
DB00203Sildenafil0Terminated1
DB00624Testosterone0Terminated1
DB00381Amlodipine1Completed1
DB06237Avanafil1Completed8
DB01151Desipramine1Completed1
DB00590Doxazosin1Completed1
DB00584Enalapril1Completed1
DB11902Gisadenafil1Completed1
DB01026Ketoconazole1Completed1
DB12573LY-24524731Completed1
DB11792Mirodenafil1Completed3
DB00218Moxifloxacin1Completed1
DB00727Nitroglycerin1Completed2
DB00338Omeprazole1Completed1
DB00503Ritonavir1Completed1
DB00412Rosiglitazone1Completed1
DB00203Sildenafil1Completed8
DB00203Sildenafil1Not Yet Recruiting1
DB00820Tadalafil1Completed2
DB00706Tamsulosin1Completed4
DB06267Udenafil1Completed3
DB00862Vardenafil1Completed2
DB08893Mirabegron1 / 2Active Not Recruiting1
DB00203Sildenafil1 / 2Completed1
DB00862Vardenafil1 / 2Recruiting1
DB00770Alprostadil2Terminated1
DB01217Anastrozole2Completed1
DB01076Atorvastatin2Not Yet Recruiting1
DB06237Avanafil2Completed1
DB01128Bicalutamide2Active Not Recruiting1
DB00083Botulinum toxin type A2Completed1
DB00766Clavulanic acid2Completed1
DB01126Dutasteride2Active Not Recruiting1
DB00016Erythropoietin2Recruiting1
DB06640Fispemifene2Active Not Recruiting1
DB06640Fispemifene2Completed1
DB05814GPI-14852Completed1
DB11902Gisadenafil2Completed1
DB12573LY-24524732Completed1
DB08893Mirabegron2Active Not Recruiting1
DB00727Nitroglycerin2Recruiting1
DB12517PF-004466872Completed1
DB00806Pentoxifylline2Not Yet Recruiting1
DB01708Prasterone2Completed1
DB00203Sildenafil2Completed4
DB00820Tadalafil2Completed3
DB00820Tadalafil2Unknown Status1
DB00675Tamoxifen2Active Not Recruiting1
DB00624Testosterone2Completed1
DB06267Udenafil2Completed2
DB06267Udenafil2Withdrawn1
DB00862Vardenafil2Completed3
DB00083Botulinum toxin type A2 / 3Recruiting1
DB00203Sildenafil2 / 3Completed1
DB00862Vardenafil2 / 3Completed1
DB00346Alfuzosin3Completed1
DB06237Avanafil3Completed6
DB04884Dapoxetine3Completed4
DB00584Enalapril3Recruiting1
DB01095Fluvastatin3Withdrawn1
DB11792Mirodenafil3Completed2
DB00727Nitroglycerin3Recruiting1
DB00806Pentoxifylline3Recruiting1
DB09292Sacubitril3Recruiting1
DB00203Sildenafil3Completed4
DB00203Sildenafil3Recruiting1
DB00203Sildenafil3Unknown Status2
DB00641Simvastatin3Completed1
DB00820Tadalafil3Completed15
DB00820Tadalafil3Recruiting1
DB00820Tadalafil3Terminated1
DB00706Tamsulosin3Completed1
DB00706Tamsulosin3Recruiting1
DB00624Testosterone3Completed1
DB06267Udenafil3Completed6
DB00862Vardenafil3Completed21
DB00770Alprostadil4Withdrawn1
DB00125Arginine4Completed1
DB06237Avanafil4Completed2
DB04884Dapoxetine4Active Not Recruiting1
DB04884Dapoxetine4Completed1
DB11927Lodenafil carbonate4Completed1
DB11927Lodenafil carbonate4Withdrawn1
DB04861Nebivolol4Unknown Status1
DB01037Selegiline4Recruiting1
DB00203Sildenafil4Active Not Recruiting1
DB00203Sildenafil4Completed31
DB00203Sildenafil4Unknown Status3
DB00864Tacrolimus4Completed1
DB00820Tadalafil4Active Not Recruiting1
DB00820Tadalafil4Completed14
DB00820Tadalafil4Recruiting2
DB00820Tadalafil4Unknown Status1
DB00624Testosterone4Completed3
DB00624Testosterone4Unknown Status1
DB13946Testosterone undecanoate4Completed1
DB13946Testosterone undecanoate4Unknown Status1
DB00862Vardenafil4Completed19
DB00862Vardenafil4Recruiting1
DB00862Vardenafil4Unknown Status3
DB01392Yohimbine4Completed1
DB00346AlfuzosinNot AvailableUnknown Status1
DB00770AlprostadilNot AvailableActive Not Recruiting1
DB00770AlprostadilNot AvailableCompleted1
DB00770AlprostadilNot AvailableUnknown Status1
DB00125ArginineNot AvailableCompleted1
DB01373CalciumNot AvailableCompleted1
DB01212CeftriaxoneNot AvailableCompleted1
DB00586DiclofenacNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB11792MirodenafilNot AvailableTerminated1
DB00704NaltrexoneNot AvailableCompleted1
DB00203SildenafilNot AvailableActive Not Recruiting1
DB00203SildenafilNot AvailableCompleted2
DB00203SildenafilNot AvailableTerminated1
DB00203SildenafilNot AvailableUnknown Status2
DB00820TadalafilNot AvailableCompleted2
DB00820TadalafilNot AvailableUnknown Status1
DB00862VardenafilNot AvailableCompleted5
DB00862VardenafilNot AvailableTerminated1
DB00661VerapamilNot AvailableCompleted1
DB01392YohimbineNot AvailableCompleted1