Calcium Nephrolithiasis

Also known as: Calcium nephrolithiasis / Nephrolithiasis / Kidney calculus / Renal lithiasis / Nephrolithiasis NOS

DrugDrug NameDrug Description
DB00594AmilorideA pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
DB00999HydrochlorothiazideA thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
DrugDrug NamePhaseStatusCount
DB00153Ergocalciferol2 / 3Withdrawn1
DB00999Hydrochlorothiazide2 / 3Terminated1
DB11094Vitamin D2 / 3Withdrawn1
DB00316Acetaminophen3Recruiting1
DB00999Hydrochlorothiazide3Recruiting1
DB00465Ketorolac3Recruiting1
DB06792Lanthanum carbonate3Recruiting1
DB00497Oxycodone3Recruiting1
DB00415Ampicillin4Active Not Recruiting1
DB13913Belladonna4Completed1
DB01212Ceftriaxone4Active Not Recruiting1
DB00537Ciprofloxacin4Recruiting1
DB00153Ergocalciferol4Completed1
DB00798Gentamicin4Active Not Recruiting1
DB08893Mirabegron4Recruiting1
DB00698Nitrofurantoin4Active Not Recruiting1
DB11130Opium4Completed1
DB00820Tadalafil4Enrolling by Invitation1
DB00706Tamsulosin4Completed1
DB00706Tamsulosin4Enrolling by Invitation1
DB00706Tamsulosin4Recruiting1
DB00302Tranexamic acid4Recruiting1
DB00512Vancomycin4Active Not Recruiting1
DB00802AlfentanilNot AvailableCompleted1
DB00415AmpicillinNot AvailableRecruiting1
DB00687FludrocortisoneNot AvailableCompleted1
DB00695FurosemideNot AvailableCompleted1
DB00798GentamicinNot AvailableRecruiting1
DB00698NitrofurantoinNot AvailableRecruiting1
DB00706TamsulosinNot AvailableCompleted1