End Stage Kidney Disease
Also known as: End-Stage Kidney Disease / End-Stage Kidney Disease (ESKD) / Endstage Kidney Disease / Chronic kidney disease, unspecified / End stage renal disease / Chronic kidney disease (CKD) / Chronic renal failure syndrome (disorder) / Renal failure chronic / Chronic renal failure / Kidney failure chronic / Kidney Failure, Chronic / End stage renal failure / End stage renal disease (ESRD) / End-stage renal disease (disorder)
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB16165 | Finerenone | A nonsteroidal mineralocorticoid receptor antagonist indicated to lower the risk of eGFR decline, end stage kidney disease, cardiovascular death, heart attack, and hospitalization for heart failure in chronic kidney disease associated with type 2 diabetes. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB16165 | Finerenone | Cytochrome P450 3A4 | enzyme |
| DB16165 | Finerenone | Cytochrome P450 2C8 | enzyme |
| DB16165 | Finerenone | Serum albumin | carrier |
| DB16165 | Finerenone | Mineralocorticoid receptor | target |
| DB16165 | Finerenone | Cytochrome P450 1A1 | enzyme |