Metastatic Castration Resistant Prostate Cancer

Also known as: Metastatic Castration-Resistant Prostate Cancer / Metastatic castration resistant Prostate cancer

DrugDrug NameDrug Description
DB05812AbirateroneAn antiandrogen used in the treatment of prostate cancer.
DB08899EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DrugDrug NameTargetType
DB05812AbirateroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB05812AbirateroneSerum albumincarrier
DB05812AbirateroneAlpha-1-acid glycoprotein 1carrier
DB05812AbirateroneCytochrome P450 3A4enzyme
DB05812AbirateroneBile salt sulfotransferaseenzyme
DB05812AbirateroneMultidrug resistance-associated protein 1transporter
DB05812AbirateroneCytochrome P450 2D6enzyme
DB05812AbirateroneCytochrome P450 2C8enzyme
DB05812AbirateroneCytochrome P450 1A2enzyme
DB05812AbirateroneCytochrome P450 2C19enzyme
DB05812AbirateroneCytochrome P450 2C9enzyme
DB08899EnzalutamideSerum albumincarrier
DB08899EnzalutamideCytochrome P450 2C8enzyme
DB08899EnzalutamideCytochrome P450 3A4enzyme
DB08899EnzalutamideAndrogen receptortarget
DB08899EnzalutamideCytochrome P450 2C9enzyme
DB08899EnzalutamideCytochrome P450 2C19enzyme
DB08899EnzalutamideCytochrome P450 2B6enzyme
DB08899EnzalutamideCytochrome P450 3A5enzyme
DB08899EnzalutamideP-glycoprotein 1transporter
DB08899EnzalutamideThyroxine-binding globulincarrier
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DrugDrug NamePhaseStatusCount
DB05812Abiraterone1Active Not Recruiting1
DB05812Abiraterone1Not Yet Recruiting1
DB05812Abiraterone1Recruiting1
DB11901Apalutamide1Active Not Recruiting1
DB11595Atezolizumab1Recruiting1
DB15140Bempegaldesleukin1Recruiting1
DB06772Cabazitaxel1Completed1
DB00002Cetuximab1Recruiting1
DB01248Docetaxel1Recruiting2
DB08899Enzalutamide1Completed1
DB08899Enzalutamide1Not Yet Recruiting1
DB08899Enzalutamide1Recruiting3
DB13982Lutetium Lu-1771Recruiting2
DB01204Mitoxantrone1Completed1
DB09035Nivolumab1Recruiting2
DB09074Olaparib1Recruiting1
DB00019Pegfilgrastim1Completed1
DB09037Pembrolizumab1Recruiting2
DB00635Prednisone1Active Not Recruiting1
DB00635Prednisone1Completed1
DB00635Prednisone1Recruiting1
DB12332Rucaparib1Not Yet Recruiting1
DB05812Abiraterone1 / 2Recruiting1
DB11648Afuresertib1 / 2Recruiting1
DB14707Cemiplimab1 / 2Recruiting1
DB05094Enzalutamide1 / 2Active Not Recruiting1
DB08899Enzalutamide1 / 2Active Not Recruiting2
DB08899Enzalutamide1 / 2Recruiting2
DB13982Lutetium Lu-1771 / 2Recruiting1
DB09035Nivolumab1 / 2Not Yet Recruiting1
DB09037Pembrolizumab1 / 2Recruiting1
DB00635Prednisone1 / 2Recruiting1
DB12813Radium Ra-2231 / 2Not Yet Recruiting1
DB05812Abiraterone2Active Not Recruiting2
DB05812Abiraterone2Completed1
DB05812Abiraterone2Recruiting3
DB00787Acyclovir2Completed1
DB11901Apalutamide2Recruiting1
DB11945Avelumab2Recruiting1
DB06772Cabazitaxel2Completed1
DB08889Carfilzomib2Completed1
DB01234Dexamethasone2Completed1
DB01248Docetaxel2Not Yet Recruiting1
DB01248Docetaxel2Recruiting1
DB08899Enzalutamide2Active Not Recruiting2
DB05094Enzalutamide2Completed1
DB08899Enzalutamide2Completed1
DB08899Enzalutamide2Not Yet Recruiting1
DB08899Enzalutamide2Recruiting2
DB05094Enzalutamide2Withdrawn1
DB08899Enzalutamide2Withdrawn1
DB13146Fluciclovine (18F)2Not Yet Recruiting1
DB06186Ipilimumab2Recruiting1
DB13982Lutetium Lu-1772Recruiting1
DB09035Nivolumab2Recruiting1
DB09074Olaparib2Active Not Recruiting1
DB15110Onvansertib2Recruiting1
DB09037Pembrolizumab2Active Not Recruiting1
DB09037Pembrolizumab2Recruiting1
DB00860Prednisolone2Active Not Recruiting1
DB00635Prednisone2Active Not Recruiting1
DB00635Prednisone2Completed1
DB00635Prednisone2Recruiting2
DB12813Radium Ra-2232Recruiting1
DB12332Rucaparib2Recruiting1
DB11836Sapanisertib2Completed1
DB05812Abiraterone3Active Not Recruiting2
DB05812Abiraterone3Completed1
DB05812Abiraterone3Recruiting2
DB06772Cabazitaxel3Active Not Recruiting1
DB01248Docetaxel3Active Not Recruiting2
DB01248Docetaxel3Recruiting1
DB08899Enzalutamide3Active Not Recruiting2
DB08899Enzalutamide3Recruiting1
DB09074Olaparib3Active Not Recruiting1
DB09074Olaparib3Recruiting1
DB00860Prednisolone3Active Not Recruiting1
DB00635Prednisone3Active Not Recruiting1
DB00635Prednisone3Completed1
DB12332Rucaparib3Recruiting1
DB05812Abiraterone4Completed1
DB08899Enzalutamide4Active Not Recruiting1
DB05094Enzalutamide4Completed1
DB08899Enzalutamide4Completed1
DB08899Enzalutamide4Terminated1
DB00860Prednisolone4Completed1
DB01248DocetaxelNot AvailableCompleted1
DB05094EnzalutamideNot AvailableApproved for Marketing1
DB08899EnzalutamideNot AvailableApproved for Marketing1
DB08899EnzalutamideNot AvailableCompleted3
DB08913Radium Ra 223 DichlorideNot AvailableActive Not Recruiting1
DB09566Radium Ra 223 DichlorideNot AvailableActive Not Recruiting1
DB01268SunitinibNot AvailableCompleted1