Steroid-Refractory Chronic GVHD
Also known as: Chronic, steroid refractory Graft versus host disease / Steroid refractory Chronic graft versus host disease / Chronic, steroid refractory Graft-Versus-Host Disease
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB09053 | Ibrutinib | An antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia. |
| DB00552 | Pentostatin | An adenosine deaminase inhibitor used to treat hairy cell leukemia. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB09053 | Ibrutinib | Tyrosine-protein kinase BTK | target |
| DB09053 | Ibrutinib | Cytochrome P450 3A4 | enzyme |
| DB09053 | Ibrutinib | Cytochrome P450 3A5 | enzyme |
| DB09053 | Ibrutinib | Serum albumin | carrier |
| DB09053 | Ibrutinib | alpha1-acid glycoprotein | carrier |
| DB09053 | Ibrutinib | Cytochrome P450 2D6 | enzyme |
| DB00552 | Pentostatin | Adenosine deaminase | target |