Idiopathic Hypogonadotropic Hypogonadism

Also known as: Central hypogonadism / Hypogonadotropic Hypogonadism / Kallman syndrome / Fertile eunuch syndrome / Secondary hypogonadism / Hypogonadotrophic hypogonadism / Gonadotrophin deficiency

DrugDrug NameDrug Description
DB09126Chorionic Gonadotropin (Human)A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women.
DB01185FluoxymesteroneA synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women.
DB00044Lutropin alfaA form of recombinant human luteinizing hormone used to treat female infertility due to hypothalamic or pituitary insufficiency, or due to profound luteinizing hormone deficiency.
DB06710MethyltestosteroneA synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
DB00624TestosteroneA hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.
DB00094UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
DrugDrug NameTargetType
DB09126Chorionic Gonadotropin (Human)Lutropin-choriogonadotropic hormone receptortarget
DB01185FluoxymesteroneSex hormone-binding globulincarrier
DB01185FluoxymesteroneEstrogen receptor alphatarget
DB01185FluoxymesteroneAndrogen receptortarget
DB01185FluoxymesteroneGlucocorticoid receptortarget
DB01185FluoxymesteroneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB00044Lutropin alfaLutropin-choriogonadotropic hormone receptortarget
DB06710MethyltestosteroneCytochrome P450 2B6enzyme
DB06710MethyltestosteroneCytochrome P450 3A4enzyme
DB06710MethyltestosteroneAndrogen receptortarget
DB06710MethyltestosteroneSolute carrier organic anion transporter family member 1A2transporter
DB06710MethyltestosteroneSolute carrier family 22 member 8transporter
DB06710MethyltestosteroneSerum albumincarrier
DB06710MethyltestosteroneSex hormone-binding globulincarrier
DB06710MethyltestosteroneEstrogen receptor alphatarget
DB06710MethyltestosteroneCytochrome P450 19A1enzyme
DB00624TestosteroneAndrogen receptortarget
DB00624TestosteroneCytochrome P450 3A4enzyme
DB00624TestosteroneCytochrome P450 19A1enzyme
DB00624TestosteroneAmine oxidase [flavin-containing] Aenzyme
DB00624TestosteroneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00624TestosteroneSerum albumincarrier
DB00624TestosteroneSex hormone-binding globulincarrier
DB00624TestosteroneCytochrome P450 3A5enzyme
DB00624TestosteroneCytochrome P450 3A7enzyme
DB00624TestosteroneSolute carrier family 22 member 8transporter
DB00624TestosteroneSolute carrier family 22 member 7transporter
DB00624TestosteroneSodium/bile acid cotransportertransporter
DB00624TestosteroneATP-binding cassette sub-family G member 2transporter
DB00624TestosteroneCytochrome P450 1A1enzyme
DB00624TestosteroneCytochrome P450 1B1enzyme
DB00624TestosteroneCytochrome P450 2A13enzyme
DB00624TestosteroneCytochrome P450 2B6enzyme
DB00624TestosteroneCytochrome P450 2C19enzyme
DB00624TestosteroneCytochrome P450 2C8enzyme
DB00624TestosteroneCytochrome P450 2C9enzyme
DB00624TestosteroneCytochrome P450 3A43enzyme
DB00624TestosteroneEstrogen receptor alphatarget
DB00624TestosteroneMineralocorticoid receptortarget
DB00624TestosteroneSolute carrier organic anion transporter family member 1B3transporter
DB00094UrofollitropinFollicle-stimulating hormone receptortarget
DrugDrug NamePhaseStatusCount
DB01217Anastrozole1Terminated1
DB00644Gonadorelin1Recruiting4
DB01183Naloxone1Recruiting1
DB00624Testosterone1Terminated1
DB00882Clomifene2Completed1
DB00882Clomifene2Terminated1
DB00644Gonadorelin2Recruiting1
DB11975TAK-4482Completed1
DB00624Testosterone2Terminated1
DB00644Gonadorelin2 / 3Active Not Recruiting1
DB01006Letrozole2 / 3Active Not Recruiting1
DB09126Chorionic Gonadotropin (Human)3Completed2
DB09066Corifollitropin alfa3Completed2
DB00624Testosterone3Completed1
DB09126Chorionic Gonadotropin (Human)4Completed2
DB09126Chorionic Gonadotropin (Human)4Recruiting1
DB09126Chorionic Gonadotropin (Human)4Terminated1
DB09126Chorionic Gonadotropin (Human)4Unknown Status1
DB00066Follitropin4Completed1
DB09024Follitropin4Terminated1
DB00644Gonadorelin4Unknown Status1
DB14741Luteinizing hormone4Terminated1
DB00044Lutropin alfa4Terminated1
DB00624Testosterone4Completed1
DB13944Testosterone enanthate4Completed1
DB09145Water4Completed1
DB01593Zinc4Completed1
DB09126Chorionic Gonadotropin (Human)Not AvailableCompleted2
DB09024FollitropinNot AvailableCompleted1
DB00644GonadorelinNot AvailableActive Not Recruiting1
DB00644GonadorelinNot AvailableRecruiting2
DB00044Lutropin alfaNot AvailableCompleted1
DB00032MenotropinsNot AvailableCompleted1
DB00624TestosteroneNot AvailableCompleted1
DB09145WaterNot AvailableCompleted2