Adrenergic Alpha-Antagonists

Also known as: Product containing alpha adrenergic receptor antagonist (product) / Substance with alpha adrenergic receptor antagonist mechanism of action (substance)

Drug	Drug Name	Drug Description
DB00692	Phentolamine	An alpha-adrenergic blocker used to treat hypertensive episodes, diagnose pheochromocytoma, treat norepinephrine administration site reactions, and reverse soft tissue anesthesia and mydriasis.
DB00571	Propranolol	A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.

Drug	Drug Name	Target	Type
DB00692	Phentolamine	Alpha-1 adrenergic receptors	target
DB00692	Phentolamine	Alpha-2 adrenergic receptors	target
DB00692	Phentolamine	ATP-sensitive inward rectifier potassium channel 11	target
DB00571	Propranolol	Beta-1 adrenergic receptor	target
DB00571	Propranolol	Beta-2 adrenergic receptor	target
DB00571	Propranolol	Beta-3 adrenergic receptor	target
DB00571	Propranolol	5-hydroxytryptamine receptor 1A	target
DB00571	Propranolol	5-hydroxytryptamine receptor 1B	target
DB00571	Propranolol	Cytochrome P450 1A2	enzyme
DB00571	Propranolol	Cytochrome P450 2D6	enzyme
DB00571	Propranolol	Alpha-1-acid glycoprotein 1	carrier
DB00571	Propranolol	Cytochrome P450 2C19	enzyme
DB00571	Propranolol	Cytochrome P450 3A4	enzyme
DB00571	Propranolol	Cytochrome P450 3A5	enzyme
DB00571	Propranolol	Cytochrome P450 3A7	enzyme
DB00571	Propranolol	Solute carrier family 22 member 2	transporter
DB00571	Propranolol	P-glycoprotein 1	transporter
DB00571	Propranolol	Cytochrome P450 1A1	enzyme
DB00571	Propranolol	Amine oxidase [flavin-containing] A	enzyme
DB00571	Propranolol	Serum albumin	carrier

Drug	Drug Name	Phase	Status	Count
DB14360	Saw palmetto	Not Available	Unknown Status	1