High Cholesterol

Also known as: High Blood Cholesterol Level / Hypercholesterolemia / Hypercholesteremia / Hypercholesterolaemia / Congenital xanthoma / Hypercholesteraemia / Elevated cholesterol

DrugDrug NameDrug Description
DB01076AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB00227LovastatinAn HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
DB00175PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
DB00641SimvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
DrugDrug NameTargetType
DB01076Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01076AtorvastatinCytochrome P450 3A4enzyme
DB01076AtorvastatinDipeptidyl peptidase 4target
DB01076AtorvastatinCytochrome P450 2D6enzyme
DB01076AtorvastatinCytochrome P450 2C9enzyme
DB01076AtorvastatinCytochrome P450 2C19enzyme
DB01076AtorvastatinCytochrome P450 3A5enzyme
DB01076AtorvastatinCytochrome P450 3A7enzyme
DB01076AtorvastatinP-glycoprotein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01076AtorvastatinMultidrug resistance-associated protein 4transporter
DB01076AtorvastatinMultidrug resistance-associated protein 5transporter
DB01076AtorvastatinMultidrug resistance-associated protein 1transporter
DB01076AtorvastatinCytochrome P450 2B6enzyme
DB01076AtorvastatinCytochrome P450 2C8enzyme
DB01076AtorvastatinAryl hydrocarbon receptortarget
DB01076AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01076AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01076AtorvastatinCanalicular multispecific organic anion transporter 1transporter
DB01076AtorvastatinBile salt export pumptransporter
DB01076AtorvastatinSerum albumincarrier
DB01076AtorvastatinHistone deacetylase 2target
DB01076AtorvastatinNuclear receptor subfamily 1 group I member 3target
DB00227Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00227LovastatinCytochrome P450 3A4enzyme
DB00227LovastatinCytochrome P450 2C8enzyme
DB00227LovastatinIntegrin alpha-Ltarget
DB00227LovastatinHistone deacetylase 2target
DB00227LovastatinSerum paraoxonase/lactonase 3enzyme
DB00227LovastatinP-glycoprotein 1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1A2transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B1transporter
DB00227LovastatinUDP-glucuronosyltransferase 1-1enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-3enzyme
DB00227LovastatinUDP-glucuronosyltransferase 2B7enzyme
DB00227LovastatinCanalicular multispecific organic anion transporter 1transporter
DB00227LovastatinBile salt export pumptransporter
DB00227LovastatinSerum albumincarrier
DB00227LovastatinCytochrome P450 2C19enzyme
DB00227LovastatinSolute carrier organic anion transporter family member 2B1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B3transporter
DB00175Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00175PravastatinSolute carrier organic anion transporter family member 2B1transporter
DB00175PravastatinP-glycoprotein 1transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1A2transporter
DB00175PravastatinSolute carrier family 22 member 6transporter
DB00175PravastatinSolute carrier family 22 member 8transporter
DB00175PravastatinCanalicular multispecific organic anion transporter 1transporter
DB00175PravastatinSolute carrier family 22 member 11transporter
DB00175PravastatinATP-binding cassette sub-family G member 2transporter
DB00175PravastatinSolute carrier family 22 member 7transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B1transporter
DB00175PravastatinMonocarboxylate transporter 1transporter
DB00175PravastatinBile salt export pumptransporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B3transporter
DB00175PravastatinHistone deacetylase 2target
DB00641Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00641SimvastatinCytochrome P450 3A4enzyme
DB00641SimvastatinCytochrome P450 2C8enzyme
DB00641SimvastatinCytochrome P450 2C9enzyme
DB00641SimvastatinCytochrome P450 3A5enzyme
DB00641SimvastatinP-glycoprotein 1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1A2transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B1transporter
DB00641SimvastatinCytochrome P450 2B6enzyme
DB00641SimvastatinCytochrome P450 2D6enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-1enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-3enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 2B7enzyme
DB00641SimvastatinCanalicular multispecific organic anion transporter 1transporter
DB00641SimvastatinIntegrin alpha-Ltarget
DB00641SimvastatinBile salt export pumptransporter
DB00641SimvastatinCytochrome P450 2C19enzyme
DB00641SimvastatinSolute carrier organic anion transporter family member 2B1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B3transporter
DB00641SimvastatinHistone deacetylase 2target
DrugDrug NamePhaseStatusCount
DB00973Ezetimibe0Completed1
DB09302Alirocumab1Completed10
DB06630Anacetrapib1Completed1
DB01076Atorvastatin1Completed6
DB12456Bococizumab1Completed5
DB12456Bococizumab1Terminated1
DB00973Ezetimibe1Completed7
DB01039Fenofibrate1Completed1
DB15089Frovocimab1Completed1
DB05123Gemcabene1Completed3
DB11789Hyodeoxycholic Acid1Unknown Status1
DB11629Laropiprant1Completed1
DB00627Niacin1Completed2
DB14862PF-068153451Terminated1
DB08860Pitavastatin1Completed1
DB06817Raltegravir1Completed1
DB01098Rosuvastatin1Completed2
DB00641Simvastatin1Completed3
DB00877Sirolimus1Completed1
DB09153Sodium chloride1Terminated1
DB00864Tacrolimus1Completed1
DB06205Vorhyaluronidase alfa1Terminated1
DB126293,5-diiodothyropropionic acid1 / 2Terminated1
DB09302Alirocumab2Completed6
DB09302Alirocumab2Recruiting1
DB09302Alirocumab2Unknown Status1
DB11780Allicin2Withdrawn1
DB06630Anacetrapib2Terminated1
DB00125Arginine2Completed1
DB01076Atorvastatin2Completed15
DB01076Atorvastatin2Not Yet Recruiting1
DB01076Atorvastatin2Recruiting2
DB01076Atorvastatin2Terminated1
DB11936Bempedoic acid2Completed7
DB06698Betahistine2Terminated1
DB12456Bococizumab2Completed4
DB01432Cholestyramine2Completed1
DB00930Colesevelam2Completed1
DB05035Eprotirome2Completed1
DB00783Estradiol2Completed1
DB15354Evinacumab2Recruiting1
DB09303Evolocumab2Completed2
DB00973Ezetimibe2Completed8
DB05449FM-VP42Completed1
DB12469Fasudil2Completed1
DB01039Fenofibrate2Completed1
DB01095Fluvastatin2Completed1
DB15089Frovocimab2Completed1
DB05123Gemcabene2Completed5
DB11629Laropiprant2Completed1
DB00166Lipoic acid2Completed1
DB08827Lomitapide2Completed3
DB00227Lovastatin2Completed2
DB05192MB078112Withdrawn1
DB00331Metformin2Completed2
DB00959Methylprednisolone2Not Yet Recruiting1
DB05528Mipomersen2Completed4
DB00627Niacin2Completed2
DB11133Omega-3 fatty acids2Completed1
DB08860Pitavastatin2Completed1
DB00175Pravastatin2Completed4
DB01098Rosuvastatin2Completed2
DB00658Sevelamer2Completed1
DB00641Simvastatin2Completed1
DB05317TAK-4752Completed1
DB05317TAK-4752Terminated1
DB12435Tipelukast2Completed1
DB00284Acarbose3Completed1
DB09302Alirocumab3Active Not Recruiting2
DB09302Alirocumab3Completed18
DB09302Alirocumab3Recruiting2
DB00381Amlodipine3Completed3
DB00381Amlodipine3Not Yet Recruiting1
DB06630Anacetrapib3Completed2
DB01076Atorvastatin3Active Not Recruiting2
DB01076Atorvastatin3Completed46
DB01076Atorvastatin3Recruiting2
DB01076Atorvastatin3Terminated7
DB11936Bempedoic acid3Active Not Recruiting1
DB11936Bempedoic acid3Completed4
DB00542Benazepril3Completed1
DB00796Candesartan cilexetil3Completed1
DB01136Carvedilol3Completed1
DB00310Chlorthalidone3Completed2
DB01432Cholestyramine3Active Not Recruiting1
DB01432Cholestyramine3Recruiting1
DB00930Colesevelam3Completed1
DB00286Conjugated estrogens3Completed1
DB00343Diltiazem3Completed1
DB00590Doxazosin3Completed1
DB00783Estradiol3Completed1
DB11655Evacetrapib3Terminated2
DB09303Evolocumab3Completed7
DB00973Ezetimibe3Active Not Recruiting3
DB00973Ezetimibe3Completed66
DB00973Ezetimibe3Not Yet Recruiting1
DB00973Ezetimibe3Recruiting1
DB00973Ezetimibe3Terminated4
DB00973Ezetimibe3Unknown Status1
DB01023Felodipine3Completed1
DB01039Fenofibrate3Active Not Recruiting1
DB01039Fenofibrate3Completed3
DB01039Fenofibrate3Recruiting1
DB13873Fenofibric acid3Completed1
DB01095Fluvastatin3Active Not Recruiting1
DB01095Fluvastatin3Completed2
DB01095Fluvastatin3Recruiting1
DB01095Fluvastatin3Terminated1
DB00695Furosemide3Completed1
DB00222Glimepiride3Completed1
DB01275Hydralazine3Completed1
DB00999Hydrochlorothiazide3Completed1
DB01306Insulin aspart3Completed1
DB01307Insulin detemir3Completed1
DB00047Insulin glargine3Completed1
DB00030Insulin human3Completed1
DB01029Irbesartan3Completed1
DB11629Laropiprant3Completed2
DB11629Laropiprant3Unknown Status1
DB12448Lifibrol3Completed1
DB00722Lisinopril3Completed2
DB00227Lovastatin3Active Not Recruiting1
DB00227Lovastatin3Completed2
DB00227Lovastatin3Recruiting1
DB00227Lovastatin3Terminated1
DB00603Medroxyprogesterone acetate3Completed1
DB00331Metformin3Completed2
DB00264Metoprolol3Completed1
DB05528Mipomersen3Completed5
DB00627Niacin3Active Not Recruiting1
DB00627Niacin3Completed6
DB00627Niacin3Recruiting1
DB00627Niacin3Unknown Status1
DB11133Omega-3 fatty acids3Active Not Recruiting1
DB11133Omega-3 fatty acids3Recruiting1
DB14377Palm oil3Terminated1
DB01132Pioglitazone3Completed1
DB08860Pitavastatin3Completed6
DB00175Pravastatin3Active Not Recruiting1
DB00175Pravastatin3Completed4
DB00175Pravastatin3Recruiting1
DB00175Pravastatin3Terminated1
DB00396Progesterone3Completed1
DB00178Ramipril3Completed1
DB00912Repaglinide3Completed1
DB00206Reserpine3Completed1
DB00412Rosiglitazone3Completed1
DB01098Rosuvastatin3Active Not Recruiting2
DB01098Rosuvastatin3Completed36
DB01098Rosuvastatin3Not Yet Recruiting1
DB01098Rosuvastatin3Recruiting1
DB01098Rosuvastatin3Terminated3
DB01098Rosuvastatin3Unknown Status1
DB00641Simvastatin3Active Not Recruiting1
DB00641Simvastatin3Completed41
DB00641Simvastatin3Recruiting1
DB00641Simvastatin3Terminated5
DB11325Soy sterol3Completed1
DB05317TAK-4753Completed6
DB05317TAK-4753Terminated4
DB00966Telmisartan3Active Not Recruiting1
DB00966Telmisartan3Not Yet Recruiting1
DB01162Terazosin3Completed1
DB12647Tocotrienol3Terminated1
DB06281Torcetrapib3Completed1
DB06281Torcetrapib3Terminated1
DB00384Triamterene3Completed1
DB00177Valsartan3Completed4
DB09302Alirocumab4Active Not Recruiting1
DB09302Alirocumab4Completed2
DB00381Amlodipine4Completed2
DB01076Atorvastatin4Active Not Recruiting1
DB01076Atorvastatin4Completed29
DB01076Atorvastatin4Terminated3
DB01076Atorvastatin4Unknown Status1
DB01393Bezafibrate4Completed1
DB00930Colesevelam4Completed6
DB00375Colestipol4Completed1
DB11874Crocin4Completed1
DB06292Dapagliflozin4Completed1
DB00973Ezetimibe4Completed28
DB00973Ezetimibe4Recruiting2
DB00973Ezetimibe4Terminated2
DB00973Ezetimibe4Unknown Status2
DB01039Fenofibrate4Completed2
DB01095Fluvastatin4Completed2
DB01095Fluvastatin4Unknown Status1
DB11629Laropiprant4Completed2
DB00238Nevirapine4Completed1
DB00627Niacin4Completed3
DB11133Omega-3 fatty acids4Completed1
DB11133Omega-3 fatty acids4Unknown Status1
DB09539Omega-3-acid ethyl esters4Completed1
DB09539Omega-3-acid ethyl esters4Unknown Status1
DB08860Pitavastatin4Completed6
DB11097Plantago seed4Completed1
DB00175Pravastatin4Completed5
DB00175Pravastatin4Unknown Status1
DB00503Ritonavir4Completed1
DB01098Rosuvastatin4Completed11
DB01098Rosuvastatin4Recruiting1
DB01098Rosuvastatin4Terminated2
DB01098Rosuvastatin4Unknown Status2
DB00641Simvastatin4Completed21
DB00641Simvastatin4Recruiting1
DB00641Simvastatin4Unknown Status1
DB00177Valsartan4Completed1
DB00945Acetylsalicylic acidNot AvailableCompleted2
DB00802AlfentanilNot AvailableRecruiting1
DB09302AlirocumabNot AvailableNot Yet Recruiting1
DB09302AlirocumabNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic acidNot AvailableRecruiting1
DB00381AmlodipineNot AvailableCompleted1
DB01060AmoxicillinNot AvailableCompleted1
DB01076AtorvastatinNot AvailableCompleted7
DB01076AtorvastatinNot AvailableUnknown Status1
DB00559BosentanNot AvailableRecruiting1
DB13015CardarineNot AvailableCompleted1
DB01413CefepimeNot AvailableRecruiting1
DB04540CholesterolNot AvailableTerminated1
DB01432CholestyramineNot AvailableCompleted1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00758ClopidogrelNot AvailableUnknown Status1
DB00363ClozapineNot AvailableRecruiting1
DB09303EvolocumabNot AvailableNot Yet Recruiting1
DB00973EzetimibeNot AvailableCompleted11
DB00973EzetimibeNot AvailableTerminated1
DB01095FluvastatinNot AvailableCompleted1
DB00828FosfomycinNot AvailableRecruiting1
DB00502HaloperidolNot AvailableRecruiting1
DB00598LabetalolNot AvailableRecruiting1
DB11629LaropiprantNot AvailableTerminated1
DB00227LovastatinNot AvailableCompleted1
DB08815LurasidoneNot AvailableRecruiting1
DB00331MetforminNot AvailableWithdrawn1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB00627NiacinNot AvailableCompleted1
DB00627NiacinNot AvailableTerminated1
DB01115NifedipineNot AvailableRecruiting1
DB11220OctacosanolNot AvailableCompleted1
DB00497OxycodoneNot AvailableRecruiting1
DB00312PentobarbitalNot AvailableRecruiting1
DB00319PiperacillinNot AvailableRecruiting1
DB08860PitavastatinNot AvailableTerminated1
DB00175PravastatinNot AvailableCompleted4
DB00175PravastatinNot AvailableTerminated1
DB00728RocuroniumNot AvailableRecruiting1
DB01098RosuvastatinNot AvailableCompleted4
DB01098RosuvastatinNot AvailableTerminated1
DB01098RosuvastatinNot AvailableUnknown Status1
DB00658SevelamerNot AvailableRecruiting1
DB00641SimvastatinNot AvailableCompleted8
DB00641SimvastatinNot AvailableUnknown Status1
DB00421SpironolactoneNot AvailableRecruiting1
DB01606TazobactamNot AvailableRecruiting1
DB00300Tenofovir disoproxilNot AvailableCompleted1
DB00684TobramycinNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB01339VecuroniumNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1
DB14038beta-SitosterolNot AvailableCompleted1