High Cholesterol Completed Phase 3 Trials for Mipomersen (DB05528)

Also known as: High Blood Cholesterol Level / Hypercholesterolemia / Hypercholesteremia / Hypercholesterolaemia / Congenital xanthoma / Hypercholesteraemia / Elevated cholesterol

IndicationStatusPhase
DBCOND0037835 (High Cholesterol)Completed3
clinicaltrials.gov IdentifierTitlePurposeDrugs
NCT01475825A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein CholesterolTreatment
NCT00794664Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on ApheresisTreatment
NCT00770146Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic PatientsTreatment
NCT00694109An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-HypercholesterolemiaTreatment
NCT00607373Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial HypercholesterolemiaTreatment