Fevers

Also known as: Fever / Hyperthermia / Body temperature increased / Fever NOS / Feverish / High temperature / Pyrexial / Pyrexia NOS / Temperature elevation / Pyrexia

DrugDrug NameDrug Description
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB14006Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
DB11278DL-MethylephedrineUsed as an antitussive and decongestant .
DB01050IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DB00939Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
DB00788NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DrugDrug NameTargetType
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Btarget
DB14006Choline salicylateAcetylcholinesterasetarget
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Atarget
DB14006Choline salicylatePhospholipase D2target
DB14006Choline salicylateCholinesterasetarget
DB14006Choline salicylatePhospholipase D1target
DB14006Choline salicylatePhosphoethanolamine/phosphocholine phosphatasetarget
DB14006Choline salicylateSolute carrier family 22 member 2transporter
DB14006Choline salicylateSolute carrier family 22 member 1transporter
DB14006Choline salicylateSolute carrier family 22 member 3transporter
DB14006Choline salicylateSolute carrier family 22 member 5transporter
DB14006Choline salicylateSolute carrier family 22 member 4transporter
DB14006Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
DB14006Choline salicylateCholine transporter-like protein 1transporter
DB14006Choline salicylateCholine transporter-like protein 4transporter
DB14006Choline salicylateCholine transporter-like protein 2transporter
DB14006Choline salicylateCholine transporter-like protein 3transporter
DB14006Choline salicylateCholine/ethanolamine kinaseenzyme
DB14006Choline salicylateCholine O-acetyltransferaseenzyme
DB14006Choline salicylateCholine kinase alphaenzyme
DB14006Choline salicylateCholine dehydrogenase, mitochondrialenzyme
DB14006Choline salicylateHigh affinity choline transporter 1transporter
DB14006Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
DB11278DL-MethylephedrineBeta-1 adrenergic receptortarget
DB11278DL-MethylephedrineAlpha-2A adrenergic receptortarget
DB11278DL-MethylephedrineAlpha adrenergic receptortarget
DB11278DL-MethylephedrineBeta adrenergic receptortarget
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenP-glycoprotein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01050IbuprofenCytochrome P450 3A4enzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenP-glycoprotein 1transporter
DB00788NaproxenUDP-glucuronosyltransferase 1-3enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-6enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-7enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-9enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-10enzyme
DB00788NaproxenSolute carrier family 22 member 8transporter
DrugDrug NamePhaseStatusCount
DB00316Acetaminophen0Recruiting1
DB01050Ibuprofen0Recruiting1
DB00959Methylprednisolone0Terminated1
DB00316Acetaminophen1Completed2
DB01050Ibuprofen1Completed1
DB12907Mannose1Withdrawn1
DB00331Metformin1Active Not Recruiting1
DB01141Micafungin1Completed1
DB00852Pseudoephedrine1Completed1
DB00503Ritonavir1Active Not Recruiting1
DB00316Acetaminophen1 / 2Recruiting1
DB01200Bromocriptine1 / 2Recruiting1
DB12121Entospletinib1 / 2Recruiting1
DB08935Obinutuzumab1 / 2Recruiting1
DB00316Acetaminophen2Active Not Recruiting1
DB00316Acetaminophen2Recruiting2
DB00681Amphotericin B2Completed1
DB00520Caspofungin2Completed1
DB00531Cyclophosphamide2Completed1
DB00080Daptomycin2Completed1
DB01248Docetaxel2Completed1
DB00997Doxorubicin2Completed1
DB00480Lenalidomide2Active Not Recruiting1
DB00480Lenalidomide2Completed1
DB08935Obinutuzumab2Active Not Recruiting1
DB06650Ofatumumab2Completed1
DB00019Pegfilgrastim2Completed1
DB10276Rotavirus vaccine2Completed1
DB00316Acetaminophen2 / 3Completed1
DB10276Rotavirus vaccine2 / 3Completed1
DB00316Acetaminophen3Completed9
DB00316Acetaminophen3Suspended1
DB00613Amodiaquine3Completed1
DB01060Amoxicillin3Terminated1
DB06697Artemether3Completed1
DB11638Artenimol3Completed1
DB09274Artesunate3Completed1
DB00207Azithromycin3Completed1
DB00112Bevacizumab3Completed1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)3Completed1
DB10992Bordetella pertussis pertactin antigen (formaldehyde inactivated)3Completed1
DB10991Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)3Completed1
DB14733Ceftobiprole medocaril3Terminated1
DB12314Chlorproguanil3Completed1
DB00537Ciprofloxacin3Terminated1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)3Completed1
DB00250Dapsone3Completed1
DB09213Dexibuprofen3Completed1
DB01050Ibuprofen3Completed5
DB09212Loxoprofen3Completed1
DB06708Lumefantrine3Completed1
DB04817Metamizole3Suspended1
DB00019Pegfilgrastim3Completed1
DB12150Pelubiprofen3Completed1
DB06614Peramivir3Terminated1
DB13941Piperaquine3Completed1
DB05386Regramostim3Completed1
DB13085Riamet3Completed1
DB10276Rotavirus vaccine3Completed1
DB10303Rotavirus vaccine3Completed1
DB00316Acetaminophen4Completed7
DB00316Acetaminophen4Recruiting1
DB00316Acetaminophen4Terminated2
DB00316Acetaminophen4Unknown Status2
DB00945Acetylsalicylic acid4Completed1
DB01060Amoxicillin4Completed2
DB00438Ceftazidime4Not Yet Recruiting1
DB00537Ciprofloxacin4Completed1
DB00766Clavulanic acid4Completed1
DB00586Diclofenac4Terminated1
DB00254Doxycycline4Completed1
DB00303Ertapenem4Recruiting1
DB01050Ibuprofen4Completed5
DB01050Ibuprofen4Recruiting1
DB01050Ibuprofen4Unknown Status4
DB01167Itraconazole4Completed1
DB01137Levofloxacin4Completed1
DB00760Meropenem4Not Yet Recruiting1
DB04817Metamizole4Completed1
DB01165Ofloxacin4Completed1
DB15274Pertussis vaccine4Completed1
DB00319Piperacillin4Not Yet Recruiting1
DB09153Sodium chloride4Completed1
DB01606Tazobactam4Not Yet Recruiting1
DB00684Tobramycin4Completed1
DB00512Vancomycin4Not Yet Recruiting1
DB00316AcetaminophenNot AvailableCompleted1
DB00316AcetaminophenNot AvailableTerminated1
DB00316AcetaminophenNot AvailableUnknown Status1
DB00316AcetaminophenNot AvailableWithdrawn1
DB06151AcetylcysteineNot AvailableWithdrawn1
DB00479AmikacinNot AvailableCompleted1
DB00613AmodiaquineNot AvailableCompleted1
DB09274ArtesunateNot AvailableCompleted1
DB00608ChloroquineNot AvailableTerminated1
DB01147CloxacillinNot AvailableCompleted1
DB00586DiclofenacNot AvailableCompleted1
DB00986GlycopyrroniumNot AvailableCompleted1
DB00741HydrocortisoneNot AvailableCompleted1
DB01050IbuprofenNot AvailableUnknown Status2
DB00281LidocaineNot AvailableCompleted1
DB14812ProcalcitoninNot AvailableCompleted1
DB00205PyrimethamineNot AvailableTerminated1
DB01299SulfadoxineNot AvailableTerminated1