Advanced Epithelial Ovarian Cancer

Drug	Drug Name	Drug Description
DB11793	Niraparib	A poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
DB09074	Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.

Drug	Drug Name	Target	Type
DB11793	Niraparib	Poly [ADP-ribose] polymerase 1	target
DB11793	Niraparib	Poly [ADP-ribose] polymerase 2	target
DB11793	Niraparib	Carboxylesterase	enzyme
DB11793	Niraparib	Cytochrome P450 1A2	enzyme
DB11793	Niraparib	ATP-binding cassette sub-family G member 2	transporter
DB11793	Niraparib	Multidrug and toxin extrusion protein 1	transporter
DB11793	Niraparib	Multidrug and toxin extrusion protein 2	transporter
DB11793	Niraparib	P-glycoprotein 1	transporter
DB11793	Niraparib	Serum albumin	carrier
DB09074	Olaparib	Poly [ADP-ribose] polymerase 1	target
DB09074	Olaparib	Cytochrome P450 3A4	enzyme
DB09074	Olaparib	Cytochrome P450 2B6	enzyme
DB09074	Olaparib	Poly [ADP-ribose] polymerase 2	target
DB09074	Olaparib	Poly [ADP-ribose] polymerase 3	target
DB09074	Olaparib	Cytochrome P450 3A5	enzyme
DB09074	Olaparib	P-glycoprotein 1	transporter
DB09074	Olaparib	ATP-binding cassette sub-family G member 2	transporter
DB09074	Olaparib	Aldo-keto reductase family 1 member C3	target
DB09074	Olaparib	UDP-glucuronosyltransferase 1-1	enzyme
DB09074	Olaparib	Serum albumin	carrier
DB09074	Olaparib	Alpha-1-acid glycoprotein 1	carrier

Drug	Drug Name	Phase	Status	Count
DB00958	Carboplatin	1 / 2	Completed	1
DB01229	Paclitaxel	1 / 2	Completed	1
DB05975	Iniparib	2	Completed	1