Endometrial Cancers

Also known as: Endometrial Cancer / Endometrial Ca / Endometrial carcinoma (NOS) / Endometrial carcinoma / Carcinoma endometrial / Ca endometrium / Endometrial cancer NOS / Cancer of endometrium

DrugDrug NameDrug Description
DB00675TamoxifenOne of the selective estrogen receptor modulators (SERM) with tissue-specific activities for the treatment and prevention of estrogen receptor positive breast cancer. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the endometrium. [PubChem]
DrugDrug NameTargetType
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1A2enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenMultidrug resistance protein 1transporter
DB00675TamoxifenBile salt export pumptransporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DrugDrug NamePhaseStatusCount
DB01076Atorvastatin0Recruiting1
DB01254Dasatinib0Completed1
DB00973Ezetimibe0Recruiting1
DB00693Fluorescein0Recruiting1
DB00331Metformin0Completed2
DB12218AZD-53631Recruiting1
DB01217Anastrozole1Recruiting1
DB11595Atezolizumab1Active Not Recruiting1
DB00112Bevacizumab1Recruiting1
DB00136Calcitriol1Active Not Recruiting1
DB01101Capecitabine1Withdrawn1
DB00958Carboplatin1Completed4
DB00958Carboplatin1Recruiting5
DB12033Cediranib1Active Not Recruiting1
DB00515Cisplatin1Completed1
DB01248Docetaxel1Completed3
DB00997Doxorubicin1Recruiting1
DB01590Everolimus1Completed1
DB11962GSK-10596151Terminated1
DB11896Gedatolisib1Recruiting1
DB00441Gemcitabine1Completed1
DB09136Isosulfan blue1Recruiting1
DB12154Itacitinib1Recruiting1
DB00331Metformin1Completed1
DB12489Mirvetuximab Soravtansine1Recruiting1
DB09074Olaparib1Completed1
DB01229Paclitaxel1Completed3
DB01229Paclitaxel1Recruiting4
DB01229Paclitaxel1Withdrawn1
DB09037Pembrolizumab1Recruiting3
DB00642Pemetrexed1Completed1
DB11942Selinexor1Recruiting1
DB06287Temsirolimus1Active Not Recruiting1
DB06287Temsirolimus1Completed1
DB06287Temsirolimus1Unknown Status1
DB01030Topotecan1Completed3
DB04879Vatalanib1Completed1
DB00361Vinorelbine1Completed1
DB11885Anlotinib1 / 2Recruiting1
DB00958Carboplatin1 / 2Completed1
DB11714Durvalumab1 / 2Recruiting1
DB00619Imatinib1 / 2Completed1
DB12674Lurbinectedin1 / 2Recruiting1
DB00351Megestrol acetate1 / 2Unknown Status1
DB09074Olaparib1 / 2Recruiting1
DB12893Sacituzumab govitecan1 / 2Recruiting1
DB00020Sargramostim1 / 2Active Not Recruiting1
DB00945Acetylsalicylic acid2Recruiting1
DB00041Aldesleukin2Completed1
DB03496Alvocidib2Completed1
DB01143Amifostine2Completed1
DB01143Amifostine2Terminated1
DB08878Aminopterin2Unknown Status1
DB00112Bevacizumab2Completed2
DB12476CPG-528522Completed1
DB00958Carboplatin2Active Not Recruiting2
DB00958Carboplatin2Completed5
DB00958Carboplatin2Not Yet Recruiting1
DB00958Carboplatin2Recruiting2
DB00958Carboplatin2Terminated1
DB00958Carboplatin2Unknown Status2
DB00002Cetuximab2Completed1
DB00501Cimetidine2Completed1
DB00515Cisplatin2Completed3
DB00515Cisplatin2Recruiting1
DB00515Cisplatin2Terminated1
DB00531Cyclophosphamide2Recruiting1
DB11651Dactolisib2Withdrawn1
DB01406Danazol2Completed1
DB01234Dexamethasone2Completed1
DB01075Diphenhydramine2Completed1
DB01248Docetaxel2Completed2
DB01248Docetaxel2Recruiting1
DB01248Docetaxel2Unknown Status1
DB05928Dovitinib2Completed1
DB00997Doxorubicin2Completed2
DB11714Durvalumab2Recruiting1
DB05094Enzalutamide2Recruiting1
DB08899Enzalutamide2Recruiting1
DB00153Ergocalciferol2Recruiting1
DB00530Erlotinib2Completed1
DB00783Estradiol2Unknown Status1
DB00977Ethinyl Estradiol2Completed1
DB01590Everolimus2Active Not Recruiting2
DB01590Everolimus2Completed2
DB01590Everolimus2Recruiting2
DB00990Exemestane2Completed1
DB00099Filgrastim2Active Not Recruiting1
DB00544Fluorouracil2Completed1
DB00544Fluorouracil2Unknown Status1
DB00569Fondaparinux sodium2Completed1
DB00947Fulvestrant2Active Not Recruiting1
DB00441Gemcitabine2Completed3
DB11733Irofulven2Completed1
DB12437Irosustat2Completed1
DB12437Irosustat2Terminated1
DB00125L-Arginine2Completed2
DB12167LY-30234142Recruiting1
DB00448Lansoprazole2Recruiting1
DB09078Lenvatinib2Completed1
DB01006Letrozole2Active Not Recruiting2
DB01006Letrozole2Completed2
DB01006Letrozole2Recruiting2
DB00367Levonorgestrel2Completed1
DB00603Medroxyprogesterone acetate2Completed2
DB00603Medroxyprogesterone acetate2Terminated1
DB00351Megestrol acetate2Completed1
DB00351Megestrol acetate2Recruiting1
DB00331Metformin2Active Not Recruiting2
DB00331Metformin2Enrolling by Invitation1
DB00331Metformin2Withdrawn1
DB00834Mifepristone2Completed1
DB00745Modafinil2Recruiting1
DB11793Niraparib2Not Yet Recruiting1
DB00717Norethisterone2Unknown Status1
DB09389Norgestrel2Completed1
DB00526Oxaliplatin2Completed2
DB01229Paclitaxel2Active Not Recruiting2
DB01229Paclitaxel2Completed7
DB01229Paclitaxel2Not Yet Recruiting1
DB01229Paclitaxel2Recruiting3
DB01229Paclitaxel2Terminated1
DB01229Paclitaxel2Unknown Status1
DB09073Palbociclib2Recruiting1
DB09037Pembrolizumab2Recruiting2
DB00642Pemetrexed2Completed2
DB05240Pilaralisib2Completed1
DB11772Pilaralisib2Completed1
DB00396Progesterone2Unknown Status1
DB00481Raloxifene2Completed1
DB00020Sargramostim2Completed1
DB01268Sunitinib2Completed1
DB11760Talazoparib2Withdrawn1
DB00853Temozolomide2Unknown Status1
DB01041Thalidomide2Completed1
DB01030Topotecan2Completed1
DB05109Trabectedin2Completed1
DB00072Trastuzumab2Active Not Recruiting1
DB11771Tremelimumab2Recruiting1
DB12503Vintafolide2Completed1
DB11094Vitamin D2Recruiting1
DB12454Zalypsis2Terminated1
DB01593Zinc2Completed1
DB12755Zoptarelin doxorubicin2Completed1
DB00958Carboplatin3Active Not Recruiting2
DB00958Carboplatin3Recruiting1
DB00515Cisplatin3Active Not Recruiting2
DB00515Cisplatin3Completed4
DB00515Cisplatin3Terminated1
DB00286Conjugated estrogens3Terminated1
DB00997Doxorubicin3Active Not Recruiting1
DB00997Doxorubicin3Completed6
DB00997Doxorubicin3Terminated2
DB00445Epirubicin3Completed1
DB00099Filgrastim3Active Not Recruiting1
DB09560Filgrastim3Active Not Recruiting1
DB00099Filgrastim3Completed3
DB00099Filgrastim3Terminated1
DB01181Ifosfamide3Completed2
DB04845Ixabepilone3Terminated1
DB00603Medroxyprogesterone acetate3Completed1
DB00351Megestrol acetate3Terminated1
DB12117Mitometh3Active Not Recruiting1
DB00104Octreotide3Completed1
DB01229Paclitaxel3Active Not Recruiting2
DB01229Paclitaxel3Completed2
DB01229Paclitaxel3Recruiting1
DB01229Paclitaxel3Terminated2
DB00019Pegfilgrastim3Active Not Recruiting1
DB00675Tamoxifen3Completed1
DB00675Tamoxifen3Terminated1
DB00813FentanylNot AvailableCompleted1
DB00327HydromorphoneNot AvailableCompleted1
DB09374Indocyanine greenNot AvailableCompleted1
DB09374Indocyanine greenNot AvailableRecruiting1
DB09136Isosulfan blueNot AvailableCompleted1
DB00331MetforminNot AvailableRecruiting1
DB00296RopivacaineNot AvailableCompleted1