Autism, Early Infantile

Also known as: Childhood Autism / Autism, Infantile / Autism / Kanner's syndrome / Infantile autism / Early infantile autism / Autism infantile / Autistic Disorder

DrugDrug NameDrug Description
DB01238AripiprazoleAripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor. In addition to partial agonist activity at the D2 receptor, aripiprazole is also a partial agonist at the 5-HT1A receptor, and like the other atypical antipsychotics, aripiprazole displays an antagonist profile at the 5-HT2A receptor. Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.
DrugDrug NameTargetType
DB01238AripiprazoleD(2) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Atarget
DB01238AripiprazoleCytochrome P450 3A4enzyme
DB01238AripiprazoleCytochrome P450 2D6enzyme
DB01238Aripiprazole5-hydroxytryptamine receptor 1Btarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Dtarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Etarget
DB01238AripiprazoleD(1A) dopamine receptortarget
DB01238AripiprazoleD(1B) dopamine receptortarget
DB01238AripiprazoleD(3) dopamine receptortarget
DB01238AripiprazoleD(4) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Ctarget
DB01238Aripiprazole5-hydroxytryptamine receptor 3Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 6target
DB01238Aripiprazole5-hydroxytryptamine receptor 7target
DB01238AripiprazoleHistamine H1 receptortarget
DB01238AripiprazoleAlpha-1A adrenergic receptortarget
DB01238AripiprazoleAlpha-1B adrenergic receptortarget
DB01238AripiprazoleAlpha-2A adrenergic receptortarget
DB01238AripiprazoleAlpha-2B adrenergic receptortarget
DB01238AripiprazoleAlpha-2C adrenergic receptortarget
DB01238AripiprazoleMuscarinic acetylcholine receptor M1target
DB01238AripiprazoleMuscarinic acetylcholine receptor M2target
DB01238AripiprazoleMuscarinic acetylcholine receptor M3target
DB01238AripiprazoleMuscarinic acetylcholine receptor M4target
DB01238AripiprazoleMuscarinic acetylcholine receptor M5target
DB01238AripiprazoleCytochrome P450 3A5enzyme
DB01238AripiprazoleCytochrome P450 3A7enzyme
DrugDrug NamePhaseStatusCount
DB08891Arbaclofen1Terminated1
DB09128Brexpiprazole1Completed1
DB05708GTS-211Terminated1
DB08815Lurasidone1Completed1
DB00107Oxytocin1Completed1
DB01593Zinc1Completed1
DB00490Buspirone1 / 2Completed1
DB00843Donepezil1 / 2Completed1
DB12583Maltodextrin1 / 2Recruiting1
DB00566Succimer1 / 2Completed1
DB01238Aripiprazole2Completed2
DB06698Betahistine2Completed1
DB06247CX5162Completed1
DB00169Cholecalciferol2Completed1
DB00514Dextromethorphan2Completed1
DB00736Esomeprazole2Not Yet Recruiting2
DB01590Everolimus2Completed1
DB00472Fluoxetine2Withdrawn1
DB00480Lenalidomide2Completed1
DB00650Leucovorin2Terminated1
DB01065Melatonin2Completed1
DB01043Memantine2Completed4
DB01043Memantine2Terminated1
DB00107Oxytocin2Completed3
DB02789Pregnenolone2Recruiting1
DB00908Quinidine2Completed1
DB00740Riluzole2Completed1
DB00734Risperidone2Completed1
DB00877Sirolimus2Completed1
DB00566Succimer2Withdrawn1
DB12422Sulforaphane2Recruiting1
DB00313Valproic Acid2Completed1
DB00313Valproic Acid2Withdrawn2
DB00246Ziprasidone2Completed1
DB00422Methylphenidate2 / 3Completed1
DB00334Olanzapine2 / 3Completed1
DB00734Risperidone2 / 3Completed1
DB00289Atomoxetine3Completed1
DB00176Fluvoxamine3Completed1
DB00674Galantamine3Completed1
DB08815Lurasidone3Completed2
DB01043Memantine3Not Yet Recruiting1
DB00422Methylphenidate3Completed1
DB01267Paliperidone3Completed1
DB06369Secretin human3Completed1
DB06369Secretin human3Terminated1
DB01104Sertraline3Completed1
DB00313Valproic Acid3Unknown Status1
DB01238Aripiprazole4Unknown Status1
DB00289Atomoxetine4Completed1
DB00122Choline4Recruiting1
DB00028Immune Globulin Human4Active Not Recruiting1
DB00422Methylphenidate4Recruiting1
DB01017Minocycline4Completed1
DB00734Risperidone4Completed1
DB00313Valproic Acid4Unknown Status1
DB06151AcetylcysteineNot AvailableCompleted1
DB00802AlfentanilNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic AcidNot AvailableRecruiting1
DB01238AripiprazoleNot AvailableCompleted1
DB00559BosentanNot AvailableRecruiting1
DB01413CefepimeNot AvailableRecruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00363ClozapineNot AvailableRecruiting1
DB00472FluoxetineNot AvailableCompleted1
DB00828FosfomycinNot AvailableRecruiting1
DB00143GlutathioneNot AvailableCompleted1
DB00502HaloperidolNot AvailableRecruiting1
DB00598LabetalolNot AvailableRecruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB01043MemantineNot AvailableUnknown Status1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB00776OxcarbazepineNot AvailableCompleted1
DB00497OxycodoneNot AvailableRecruiting1
DB00107OxytocinNot AvailableUnknown Status1
DB00312PentobarbitalNot AvailableRecruiting1
DB00571PropranololNot AvailableRecruiting1
DB00571PropranololNot AvailableWithdrawn1
DB00728RocuroniumNot AvailableRecruiting1
DB00658SevelamerNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB01339VecuroniumNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1