Unresectable Locally Advanced NSCLC
Also known as: Unresectable, locally advanced Non-Small Cell Lung Carcinoma (NSCLC) / Locally Advanced Unresectable NSCLC
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB11791 | Capmatinib | A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB11791 | Capmatinib | Cytochrome P450 3A4 | enzyme |
| DB11791 | Capmatinib | Aldehyde oxidase | enzyme |
| DB11791 | Capmatinib | Hepatocyte growth factor receptor | target |
| DB11791 | Capmatinib | P-glycoprotein 1 | transporter |
| DB11791 | Capmatinib | Multidrug and toxin extrusion protein 1 | transporter |
| DB11791 | Capmatinib | Multidrug and toxin extrusion protein 2 | transporter |
| DB11791 | Capmatinib | Cytochrome P450 1A2 | enzyme |
| DB11791 | Capmatinib | ATP-binding cassette sub-family G member 2 | transporter |