High Blood Pressure (Hypertension) Completed Phase 3 Trials for Aliskiren (DB09026)

Also known as: HTN / Hypertension(HTN) / Hypertensive / Hypertension / High Blood Pressure / Blood High Pressure / Blood Pressure, High / High Blood Pressures / Blood pressure high / Essential (primary) hypertension / HT / HBP / Hypertension NOS / Hypertension arterial

IndicationStatusPhase
DBCOND0040789 (High Blood Pressure (Hypertension))Completed3
clinicaltrials.gov IdentifierTitlePurposeDrugs
NCT00219063A Clinical Study to Compare an Aliskiren Based Hypertensive Regimen With a Ramipril Based One Followed by a Randomized Withdrawal.Treatment
NCT00219180Clinical Study to Evaluate Efficacy and Safety of Aliskiren (150mg & 300mg) Administered Alone and in Combo With Valsartan (160mg and 320mg) in Patients With High Blood PressureTreatment
NCT00219024Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.Treatment
NCT00219076A Clinical Study to Evaluate the Safety and Efficacy of the Combination of Aliskiren and Amlodipine in Hypertensive Non Responders PatientsTreatment
NCT00171405A Clinical Study to Evaluate the Long-term Safety (12 Months) of the Combination of Aliskiren 300 mg and Hydrochlorothiazide 25 mgTreatment
NCT00219050A Clinical Study to Compare the Safety and Efficacy of an Aliskiren-based Regimen With a Lisinopril Based Regimen in Patients With Severe HypertensionTreatment
NCT00219037Long Term Safety of Aliskiren Alone or With the Optional Addition of Hydrochlorothiazide in Patients With Essential HypertensionTreatment
NCT00219141Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential HypertensionTreatment
NCT00219128A Dose Ranging Study to Compare the Safety and Efficacy of Aliskiren 150mg, 300mg, and 600mg to Placebo in Patients With High Blood Pressure.Treatment
NCT00219102A Clinical Study to Evaluate Safety & Efficacy of the Combination of Aliskiren, Valsartan & Hydrochlorothiazide in Diabetic Hypertensive Nonresponder PatientsTreatment
NCT00219115A Clinical Study to Compare Combination of Aliskiren+ HCTZ to Irbesartan+ HCTZ or Amlodipine+ HCTZ or HCTZ Alone in Obese Hypertensive Not Responsive to HCTZ 25 mgTreatment
NCT00219193A Clinical Study to Evaluate the Safety and Efficacy of the Combination of Aliskiren and Valsartan in Hypertensive Non Responders PatientsTreatment
NCT00219167A Clinical Study to Assess Efficacy and Safety of Aliskiren in the Elderly With High Blood PressureTreatment
NCT00219154A Clinical Study to Compare Long-term Efficacy and Safety of an Aliskiren Based Regimen to a Hydrochlorothiazidebased Treatment Regimen With Optional Addition of AmlodipineTreatment
NCT00260923A Dose Ranging Study to Compare the Safety and Efficacy of Aliskiren in Patients With High Blood PressureTreatment
NCT00262236Efficacy and Safety of Aliskiren and Atenolol in Adults (>18) With Mild to Moderate HypertensionTreatment
NCT00294710A Clinical Study to Compare Long-term Efficacy and Safety of an Aliskiren Based Regimen to a Hydrochlorothiazide Based Treatment Regimen With Optional Addition of AmlodipineTreatment
NCT00299832SPP100 (Aliskiren) Regimen in Hypertensive Patients With Renal DysfunctionTreatment
NCT00299806SPP100 (Aliskiren) Regimen in Patients With Severe HypertensionTreatment
NCT00344110Study Comparing SPP100 (Aliskiren) 150mg to Placebo and to Losartan 50mg in Patients With Mild to Moderate Essential HypertensionTreatment
NCT00368277A Safety and Efficacy Trial of Aliskiren 150mg , 300 mg Compared to Ramipril 5mg, 10mg in the ElderlyTreatment
NCT00387517Safety/Efficacy of Combo Therapy With Aliskiren & Hydrochlorothiazide vs Therapy With Hydrochlorothiazide Alone in Patients With HypertensionTreatment
NCT00386607A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide.Treatment
NCT00386139A Safety and Efficacy Trial of the Combination of Aliskiren / Hydrochlorothiazide (HCTZ)(300/12.5 mg and 300/25 mg) Compared to Aliskiren 300 mg in Hypertensive PatientsTreatment
NCT00402103An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood PressureTreatment
NCT00518765Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium DietBasic Science
NCT00529451Safety and Efficacy of Aliskiren 300 mg, 150 mg and 75 mg in Patients With Essential Hypertension Compared to Ramipril 5 mgTreatment
NCT00706134Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled StudyTreatment
NCT00705575Efficacy and Safety of the Combination Aliskiren (300 mg) and Hydrochlorothiazide (25mg) to Aliskiren (300mg) Monotherapy in Patients With Staged II HypertensionTreatment
NCT00739973Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Amlodipine in Essential HypertensionTreatment
NCT00765674Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe HypertensionTreatment
NCT00777946Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients Not Adequately Responding to Aliskiren AloneTreatment
NCT00797862Aliskiren and the Calcium Channel Blocker Amlodipine Combination as an Initial Treatment Strategy for HypertensionDiagnostic
NCT01150357Safety and Efficacy of Aliskiren in Pediatric Hypertensive Patients 6-17 Years of AgeTreatment
NCT01151410An Extension Study to Evaluate the Long Term Safety, Tolerability and Efficacy of Aliskiren Compared to Enalapril in Pediatric Hypertensive Patients 6-17 Years of AgeTreatment