Primary Central Nervous System Lymphoma (PCNSL)

Also known as: Primary Central Nervous System Lymphoma / Primary CNS Lymphoma (PCNSL) / PCNSL (Primary CNS Lymphoma) / Primary CNS Lymphoma / Lymphoma / Central nervous system lymphoma

DrugDrug NameDrug Description
DB00515CisplatinA platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
DB01168ProcarbazineAn antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
DB00853TemozolomideAn alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
DrugDrug NameTargetType
DB00515CisplatinDNAtarget
DB00515CisplatinCanalicular multispecific organic anion transporter 2transporter
DB00515CisplatinMultidrug resistance-associated protein 5transporter
DB00515CisplatinCanalicular multispecific organic anion transporter 1transporter
DB00515CisplatinSolute carrier family 22 member 2transporter
DB00515CisplatinHigh affinity copper uptake protein 1transporter
DB00515CisplatinProbable low affinity copper uptake protein 2transporter
DB00515CisplatinMultidrug resistance-associated protein 6transporter
DB00515CisplatinP-glycoprotein 1transporter
DB00515CisplatinCopper-transporting ATPase 2transporter
DB00515CisplatinCopper-transporting ATPase 1transporter
DB00515CisplatinProstaglandin G/H synthase 2enzyme
DB00515CisplatinMyeloperoxidaseenzyme
DB00515CisplatinXanthine dehydrogenase/oxidaseenzyme
DB00515CisplatinArylamine N-acetyltransferaseenzyme
DB00515CisplatinCytochrome P450 2C9enzyme
DB00515CisplatinCytochrome P450 2B6enzyme
DB00515CisplatinCholinesteraseenzyme
DB00515CisplatinCytochrome P450 4A11enzyme
DB00515CisplatinATP-binding cassette sub-family G member 2transporter
DB00515CisplatinGlutathione S-transferase theta-1enzyme
DB00515CisplatinMetallothionein-1Aenzyme
DB00515CisplatinMetallothionein-2enzyme
DB00515CisplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00515CisplatinGlutathione S-transferase Penzyme
DB00515CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00515CisplatinGlutathione S-transferase Mu 1enzyme
DB00515CisplatinDNA-3-methyladenine glycosylasetarget
DB00515CisplatinAlpha-2-macroglobulintarget
DB00515CisplatinSerum albumincarrier
DB00515CisplatinSerotransferrintarget
DB00515CisplatinCopper transport protein ATOX1target
DB01168ProcarbazineDNAtarget
DB01168ProcarbazineXanthine dehydrogenase/oxidaseenzyme
DB01168ProcarbazineMonoamine oxidasetarget
DB00853TemozolomideDNAtarget
DrugDrug NamePhaseStatusCount
DB14857Avadomide1Active Not Recruiting1
DB00987Cytarabine1Recruiting1
DB09053Ibrutinib1Recruiting2
DB11633Isavuconazole1Recruiting1
DB00480Lenalidomide1Recruiting1
DB08935Obinutuzumab1Recruiting1
DB00073Rituximab1Recruiting2
DB13881Tisagenlecleucel1Recruiting1
DB11581Venetoclax1Recruiting1
DB00480Lenalidomide1 / 2Recruiting1
DB00563Methotrexate1 / 2Recruiting1
DB00073Rituximab1 / 2Recruiting1
DB11850Ublituximab1 / 2Completed1
DB11702Antineoplaston A102Withdrawn1
DB14846Bimiralisib2Completed1
DB14846Bimiralisib2Withdrawn1
DB11666Buparlisib2Completed1
DB01008Busulfan2Active Not Recruiting1
DB14776Camrelizumab2Recruiting1
DB00262Carmustine2Active Not Recruiting1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00987Cytarabine2Completed1
DB00987Cytarabine2Recruiting1
DB11714Durvalumab2Withdrawn1
DB00773Etoposide2Active Not Recruiting1
DB00099Filgrastim2Completed1
DB09053Ibrutinib2Not Yet Recruiting1
DB01177Idarubicin2Completed1
DB00480Lenalidomide2Recruiting1
DB00480Lenalidomide2Withdrawn1
DB00563Methotrexate2Active Not Recruiting1
DB00563Methotrexate2Completed1
DB00563Methotrexate2Recruiting4
DB00563Methotrexate2Unknown Status1
DB00959Methylprednisolone2Unknown Status1
DB09037Pembrolizumab2Recruiting1
DB00642Pemetrexed2Withdrawn1
DB00635Prednisone2Active Not Recruiting1
DB01168Procarbazine2Recruiting1
DB00073Rituximab2Active Not Recruiting1
DB00073Rituximab2Recruiting3
DB00073Rituximab2Terminated1
DB00853Temozolomide2Recruiting3
DB00853Temozolomide2Terminated1
DB00853Temozolomide2Unknown Status1
DB04572Thiotepa2Active Not Recruiting1
DB08828Vismodegib2Terminated1
DB00563Methotrexate3Recruiting1
DB00073Rituximab3Recruiting1
DB00853Temozolomide3Recruiting1
DB00987Cytarabine4Recruiting1
DB01234Dexamethasone4Recruiting1
DB00983Formoterol4Recruiting1
DB00563Methotrexate4Recruiting1
DB00642Pemetrexed4Recruiting1
DB00073Rituximab4Recruiting1
DB00091CyclosporineNot AvailableCompleted1
DB01073FludarabineNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableCompleted1