Gilles de la Tourette's Syndrome

Also known as: Tourette’s syndrome / Gilles de la Tourette Syndrome / Tourettes Syndrome / Tourette Syndrome / Tourette's Syndrome / Gilles de la Tourette / Gilles de la Tourette's / Brissaud's II / Guinon's myospasia impulsiva / (Psychogenic tics) or (Gilles de la Tourette's syndrome) / Syndrome Gilles de la Tourette / Tourette's disorder / Gilles de la Tourette's disorder / Combined vocal and multiple motor tic disorder [de la Tourette] / Syndrome Tourette

DrugDrug NameDrug Description
DB01068ClonazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
DB00575ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
DB00623FluphenazineA phenothiazine used to treat patients requiring long-term neuroleptic therapy.
DB01018GuanfacineAn alpha-2A adrenergic receptor agonist used to treat ADHD.
DB00502HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
DB00334OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
DB04844TetrabenazineA vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington's Disease.
DrugDrug NameTargetType
DB01068ClonazepamCytochrome P450 3A4enzyme
DB01068ClonazepamSerum albumincarrier
DB01068ClonazepamCytochrome P450 2E1enzyme
DB01068ClonazepamArylamine N-acetyltransferase 2enzyme
DB01068ClonazepamGABA(A) Receptortarget
DB01068ClonazepamNuclear receptor subfamily 1 group I member 2target
DB01068ClonazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00575ClonidineAlpha-2A adrenergic receptortarget
DB00575ClonidineCytochrome P450 2D6enzyme
DB00575ClonidineAlpha-2B adrenergic receptortarget
DB00575ClonidineAlpha-2C adrenergic receptortarget
DB00575ClonidineSolute carrier family 22 member 3transporter
DB00575ClonidineSolute carrier family 22 member 5transporter
DB00575ClonidineSolute carrier family 22 member 4transporter
DB00575ClonidineP-glycoprotein 1transporter
DB00575ClonidineCytochrome P450 1A2enzyme
DB00575ClonidineCytochrome P450 3A4enzyme
DB00575ClonidineCytochrome P450 1A1enzyme
DB00575ClonidineCytochrome P450 3A5enzyme
DB00575ClonidineAlpha-1A adrenergic receptortarget
DB00575ClonidineAlpha-1B adrenergic receptortarget
DB00575ClonidineAlpha-1D adrenergic receptortarget
DB00575ClonidineSerum albumincarrier
DB00623FluphenazineDopamine D2 receptortarget
DB00623FluphenazineCalmodulintarget
DB00623FluphenazineDopamine D1 receptortarget
DB00623FluphenazineCytochrome P450 2D6enzyme
DB00623FluphenazineP-glycoprotein 1transporter
DB00623FluphenazineCytochrome P450 2E1enzyme
DB00623FluphenazineAndrogen receptortarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Atarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Ctarget
DB01018GuanfacineAlpha-2A adrenergic receptortarget
DB01018GuanfacineCytochrome P450 2C19enzyme
DB01018GuanfacineCytochrome P450 3A4enzyme
DB01018GuanfacineAlpha-2B adrenergic receptortarget
DB01018GuanfacineMultidrug and toxin extrusion protein 1transporter
DB01018GuanfacineSolute carrier family 22 member 1transporter
DB01018GuanfacineSolute carrier family 22 member 2transporter
DB00502HaloperidolDopamine D2 receptortarget
DB00502HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
DB00502HaloperidolDopamine D1 receptortarget
DB00502HaloperidolCytochrome P450 1A2enzyme
DB00502HaloperidolCytochrome P450 2D6enzyme
DB00502Haloperidol5-hydroxytryptamine receptor 2Atarget
DB00502HaloperidolDopamine D3 receptortarget
DB00502HaloperidolCytochrome P450 3A4enzyme
DB00502HaloperidolCytochrome P450 3A5enzyme
DB00502HaloperidolCytochrome P450 3A7enzyme
DB00502HaloperidolP-glycoprotein 1transporter
DB00502HaloperidolCarbonyl reductase [NADPH] 1enzyme
DB00502HaloperidolUDP-glucuronosyltransferase 1-9enzyme
DB00502HaloperidolCytochrome P450 2C19enzyme
DB00502HaloperidolCytochrome P450 2C9enzyme
DB00502HaloperidolMelanin-concentrating hormone receptor 1target
DB00502HaloperidolSynaptic vesicular amine transportertarget
DB00502Haloperidol5-hydroxytryptamine receptor 2Ctarget
DB00502HaloperidolSigma non-opioid intracellular receptor 1target
DB00502HaloperidolHistamine H1 receptortarget
DB00502HaloperidolMuscarinic acetylcholine receptor M3target
DB00502HaloperidolAlpha-1A adrenergic receptortarget
DB00502HaloperidolAlpha-2A adrenergic receptortarget
DB00502HaloperidolAlpha-2B adrenergic receptortarget
DB00502HaloperidolAlpha-2C adrenergic receptortarget
DB00502Haloperidol5-hydroxytryptamine receptor 1Atarget
DB00502Haloperidol5-hydroxytryptamine receptor 6target
DB00502Haloperidol5-hydroxytryptamine receptor 7target
DB00502HaloperidolCytochrome P450 1A1enzyme
DB00334OlanzapineDopamine D1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineDopamine D4 receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineDopamine D2 receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineDopamine D3 receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineDopamine D5 receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineP-glycoprotein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineBeta adrenergic receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 1target
DB00334OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineUDP-glucuronosyltransferase 1-4enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334OlanzapineCytochrome P450 3A Subfamilyenzyme
DB04844TetrabenazineSynaptic vesicular amine transportertarget
DB04844TetrabenazineCytochrome P450 2D6enzyme
DB04844TetrabenazineDopamine D2 receptortarget
DB04844TetrabenazineCarbonyl reductase [NADPH] 1enzyme
DrugDrug NamePhaseStatusCount
DB00260Cycloserine0Recruiting1
DB12161Deutetrabenazine1Completed1
DB01235Levodopa1Completed1
DB12012PF-044578451Terminated1
DB11915Valbenazine1Completed1
DB11917Vatiquinone1Completed1
DB12273Ecopipam1 / 2Completed1
DB00659Acamprosate2Completed1
DB06151Acetylcysteine2Completed1
DB00289Atomoxetine2Not Yet Recruiting1
DB00470Dronabinol2Completed1
DB00470Dronabinol2Not Yet Recruiting1
DB12273Ecopipam2Active Not Recruiting1
DB14009Medical Cannabis2Recruiting2
DB12201PF-036547462Withdrawn1
DB14043Palmidrol2Completed1
DB14043Palmidrol2Not Yet Recruiting1
DB01100Pimozide2Completed1
DB00413Pramipexole2Completed1
DB00734Risperidone2Completed1
DB04844Tetrabenazine2Withdrawn1
DB11915Valbenazine2Completed5
DB11915Valbenazine2Terminated2
DB12161Deutetrabenazine2 / 3Completed1
DB01238Aripiprazole3Enrolling by Invitation1
DB12161Deutetrabenazine3Active Not Recruiting1
DB12161Deutetrabenazine3Completed1
DB01018Guanfacine3Completed1
DB14011Nabiximols3Recruiting1
DB00413Pramipexole3Terminated1
DB13025Tiapride3Completed1
DB00273Topiramate3Completed2
DB01238Aripiprazole4Completed1
DB00575Clonidine4Completed1
DB00575Clonidine4Unknown Status1
DB03929D-Serine4Completed1
DB00674Galantamine4Terminated1
DB01018Guanfacine4Completed1
DB01202Levetiracetam4Completed1
DB00904Ondansetron4Recruiting1
DB00740Riluzole4Completed1
DB01238AripiprazoleNot AvailableTerminated1
DB00083Botulinum toxin type ANot AvailableRecruiting1
DB00422MethylphenidateNot AvailableCompleted1
DB01186PergolideNot AvailableCompleted1