Chordomas

Also known as: Chordoma

DrugDrug NameDrug Description
DB00619ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
DB00877SirolimusAn immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis.
DrugDrug NameTargetType
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBreakpoint cluster region proteintarget
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibP-glycoprotein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibBile salt export pumptransporter
DB00619ImatinibCytochrome P450 2C8enzyme
DB00877SirolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00877SirolimusCytochrome P450 3A4enzyme
DB00877SirolimusSerine/threonine-protein kinase mTORtarget
DB00877SirolimusFibroblast growth factor 2target
DB00877SirolimusCytochrome P450 3A5enzyme
DB00877SirolimusCytochrome P450 3A7enzyme
DB00877SirolimusP-glycoprotein 1transporter
DB00877SirolimusSolute carrier organic anion transporter family member 1B1transporter
DB00877SirolimusMultidrug and toxin extrusion protein 1transporter
DrugDrug NamePhaseStatusCount
DB01143Amifostine1Terminated1
DB01008Busulfan1Terminated1
DB00099Filgrastim1Terminated1
DB00619Imatinib1Unknown Status1
DB01042Melphalan1Terminated1
DB04868Nilotinib1Active Not Recruiting1
DB06132Nivolumab1Recruiting1
DB09035Nivolumab1Recruiting1
DB06603Panobinostat1Unknown Status1
DB00642Pemetrexed1Recruiting1
DB04572Thiotepa1Terminated1
DB06013Aldoxorubicin1 / 2Withdrawn1
DB11945Avelumab1 / 2Withdrawn1
DB00002Cetuximab1 / 2Withdrawn1
DB00531Cyclophosphamide1 / 2Withdrawn1
DB08916Afatinib2Recruiting1
DB01254Dasatinib2Completed1
DB00619Imatinib2Completed1
DB06186Ipilimumab2Recruiting1
DB09035Nivolumab2Recruiting3
DB09073Palbociclib2Recruiting1
DB14851Relatlimab2Recruiting1
DB08818Hyaluronic acidNot AvailableUnknown Status1