Human Immunodeficiency Virus Type 1 (HIV-1)

Also known as: Human Immunodeficiency Virus - Type 1 / HIV-I / HIV-1 / Human Immunodeficiency Virus Type 1 / Immunodeficiency Virus Type 1, Human / Human Immunodeficiency Virus-1 / Human Immunodeficiency Virus-1 (HIV-1) / Human Immunodeficiency Virus-Type 1 / Human Immunodeficiency Virus 1 / Human T-cell leukemia virus III / T-lymphotropic virus / Human T-cell leukaemia virus III / T-lymphotropic virus (organism) / Human immunodeficiency virus type 1 [Ambiguous] / Human immunodeficiency virus type I (organism) / Human immunodeficiency virus type I -RETIRED- / [X]Human immunodeficiency virus disease (disorder) / Human immunodeficiency virus [HIV] disease / [X]Unspecified human immunodeficiency virus [HIV] disease (disorder) / HIV disease / (AIDS) or (HIV infection) / HTLV-III/LAV infection -RETIRED- / HIV infection NOS / Human immunodeficiency virus syndrome / Human immunodeficiency virus infection, unspecified / HIV Infections / HIV infection / Human immunodeficiency virus infection (disorder)

DrugDrug NameDrug Description
DB12301DoravirineA non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections.
DB00879EmtricitabineA nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
DB00109EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
DB09299Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
DrugDrug NameTargetType
DB12301DoravirineCytochrome P450 3A4enzyme
DB12301DoravirineCytochrome P450 3A5enzyme
DB12301DoravirineReverse transcriptase/RNaseHtarget
DB00879EmtricitabineReverse transcriptase/RNaseHtarget
DB00879EmtricitabineDeoxycytidine kinaseenzyme
DB00879EmtricitabineSerum albumincarrier
DB00879EmtricitabineMultidrug and toxin extrusion protein 1transporter
DB00109EnfuvirtideEnvelope glycoproteintarget
DB00109EnfuvirtideCytochrome P450 2C19enzyme
DB00109EnfuvirtideCytochrome P450 2E1enzyme
DB09299Tenofovir alafenamideReverse transcriptase/RNaseHtarget
DB09299Tenofovir alafenamideP-glycoprotein 1transporter
DB09299Tenofovir alafenamideMultidrug resistance-associated protein 4transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 6transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 8transporter
DB09299Tenofovir alafenamideLysosomal protective proteinenzyme
DB09299Tenofovir alafenamideLiver carboxylesterase 1enzyme
DB09299Tenofovir alafenamideATP-binding cassette sub-family G member 2transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
DB09299Tenofovir alafenamideReverse transcriptasetarget
DB09299Tenofovir alafenamideDNA polymerasetarget
DB09299Tenofovir alafenamideSerum albumincarrier
DB09299Tenofovir alafenamideCytochrome P450 3A4enzyme
DB09299Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
DB09299Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
DrugDrug NamePhaseStatusCount
DB01072Atazanavir1Completed2
DB09065Cobicistat1Completed1
DB01264Darunavir1Completed1
DB12301Doravirine1Completed1
DB15653Islatravir1Completed1
DB00238Nevirapine1Completed1
DB05083Rilpivirine1Completed1
DB08864Rilpivirine1Completed2
DB05083Rilpivirine1Terminated1
DB08864Rilpivirine1Terminated1
DB00503Ritonavir1Completed1
DB00582Voriconazole1Completed1
DB08639Dapivirine1 / 2Completed1
DB01048Abacavir2Recruiting1
DB01072Atazanavir2Completed2
DB01264Darunavir2Completed4
DB00625Efavirenz2Active Not Recruiting1
DB00625Efavirenz2Completed2
DB00625Efavirenz2Terminated1
DB09101Elvitegravir2Completed1
DB00879Emtricitabine2Active Not Recruiting1
DB00879Emtricitabine2Completed3
DB00879Emtricitabine2Recruiting1
DB00109Enfuvirtide2Completed1
DB06414Etravirine2Completed3
DB06414Etravirine2Terminated2
DB11796Fostemsavir2Completed1
DB00709Lamivudine2Completed1
DB00709Lamivudine2Recruiting2
DB11649Lersivirine2Completed2
DB11649Lersivirine2Terminated2
DB01601Lopinavir2Completed1
DB04835Maraviroc2Completed2
DB11066Pancrelipase protease2Completed1
DB06817Raltegravir2Completed2
DB08864Rilpivirine2Completed1
DB05083Rilpivirine2Recruiting2
DB08864Rilpivirine2Recruiting2
DB00503Ritonavir2Completed6
DB15623TMC-3109112Completed1
DB14126Tenofovir2Completed1
DB00300Tenofovir disoproxil2Active Not Recruiting1
DB00300Tenofovir disoproxil2Completed3
DB00300Tenofovir disoproxil2Recruiting1
DB00495Zidovudine2Completed1
DB00495Zidovudine2Recruiting1
DB00879Emtricitabine2 / 3Active Not Recruiting1
DB09299Tenofovir alafenamide2 / 3Active Not Recruiting1
DB01048Abacavir3Active Not Recruiting1
DB09065Cobicistat3Active Not Recruiting1
DB09065Cobicistat3Completed1
DB01264Darunavir3Active Not Recruiting2
DB01264Darunavir3Completed1
DB01264Darunavir3Terminated1
DB12301Doravirine3Active Not Recruiting1
DB00625Efavirenz3Completed3
DB09101Elvitegravir3Completed1
DB00879Emtricitabine3Active Not Recruiting2
DB00879Emtricitabine3Completed1
DB00879Emtricitabine3Terminated1
DB06414Etravirine3Completed2
DB06414Etravirine3Recruiting1
DB01319Fosamprenavir3Terminated1
DB00709Lamivudine3Active Not Recruiting1
DB00709Lamivudine3Completed1
DB00709Lamivudine3Recruiting1
DB01601Lopinavir3Terminated1
DB04835Maraviroc3Completed1
DB04835Maraviroc3Terminated1
DB04835Maraviroc3Withdrawn1
DB11066Pancrelipase protease3Active Not Recruiting1
DB05083Rilpivirine3Completed2
DB08864Rilpivirine3Completed2
DB00503Ritonavir3Active Not Recruiting1
DB00503Ritonavir3Completed1
DB00503Ritonavir3Terminated2
DB09299Tenofovir alafenamide3Active Not Recruiting1
DB09299Tenofovir alafenamide3Completed1
DB00300Tenofovir disoproxil3Active Not Recruiting1
DB00300Tenofovir disoproxil3Terminated1
DB00495Zidovudine3Completed1
DB01048Abacavir4Completed1
DB01072Atazanavir4Completed2
DB01264Darunavir4Completed3
DB01264Darunavir4Withdrawn1
DB08930Dolutegravir4Completed1
DB00625Efavirenz4Completed2
DB00879Emtricitabine4Completed4
DB01319Fosamprenavir4Completed1
DB00709Lamivudine4Completed2
DB01601Lopinavir4Completed4
DB00238Nevirapine4Completed1
DB11066Pancrelipase protease4Completed1
DB08864Rilpivirine4Completed1
DB00503Ritonavir4Completed5
DB14126Tenofovir4Completed2
DB00300Tenofovir disoproxil4Completed3
DB00495Zidovudine4Completed1
DB00109EnfuvirtideNot AvailableCompleted1
DB04835MaravirocNot AvailableCompleted1