Acute Migraine

Also known as: Acute Migraine Headache / Migraine, Acute / Migraine NOS / Migraine headaches / Migraine headache / Migraine, unspecified / Migrainous headache / Migraine type headaches / Migraine Disorders / Migraine

DrugDrug NameDrug Description
DB00586DiclofenacA non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
DB00216EletriptanEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
DB00465KetorolacKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.[L6358][L6508][F4003][F4105][FDA Label] It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain, and ankylosing spondylitis.[F3952] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
DB00788NaproxenAn anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.
DB00669SumatriptanA serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of migraine disorders. A transdermal patch version of sumatriptan is currently in phase I trials in the U.S. under the code name NP101 (NuPathe).
DrugDrug NameTargetType
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-1enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance protein 1transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacProstaglandin G/H synthase 1enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 1A1enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacArachidonate 5-lipoxygenasetarget
DB00586DiclofenacSodium channel protein type 4 subunit alphatarget
DB00586DiclofenacAcid-sensing ion channel 1target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3target
DB00586DiclofenacPhospholipase A2, membrane associatedtarget
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00216Eletriptan5-hydroxytryptamine receptor 1Dtarget
DB00216Eletriptan5-hydroxytryptamine receptor 7target
DB00216Eletriptan5-hydroxytryptamine receptor 1Atarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Etarget
DB00216Eletriptan5-hydroxytryptamine receptor 2Btarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Ftarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Btarget
DB00216EletriptanCytochrome P450 3A4enzyme
DB00216EletriptanCytochrome P450 2D6enzyme
DB00216EletriptanCytochrome P450 2C9enzyme
DB00216EletriptanCytochrome P450 2C19enzyme
DB00216EletriptanProstaglandin G/H synthase 1enzyme
DB00216EletriptanCytochrome P450 2A6enzyme
DB00216EletriptanMultidrug resistance protein 1transporter
DB00465KetorolacProstaglandin G/H synthase 1target
DB00465KetorolacProstaglandin G/H synthase 2target
DB00465KetorolacUDP-glucuronosyltransferase 2B7enzyme
DB00465KetorolacCytochrome P450 2C8enzyme
DB00465KetorolacCytochrome P450 2C9enzyme
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-1enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenMultidrug resistance protein 1transporter
DB00669Sumatriptan5-hydroxytryptamine receptor 1Dtarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Btarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Ftarget
DB00669SumatriptanAmine oxidase [flavin-containing] Aenzyme
DB00669Sumatriptan5-hydroxytryptamine receptor 1Atarget
DB00669SumatriptanSolute carrier organic anion transporter family member 1A2transporter
DB00669SumatriptanMultidrug resistance protein 1transporter
DB00669SumatriptanATP-binding cassette sub-family G member 2transporter
DB00669SumatriptanSolute carrier organic anion transporter family member 1B1transporter