Lesch-Nyhan Disease

Also known as: Hypoxanthine-guanine phosphoribosyl transferase deficiency / Lesch-Nyhan Syndrome / Lesch-Nyhan syndrome (disorder) / Deficiency of hypoxanthine phosphoribosyltransferase (disorder) / HGPRT deficiency / Total hypoxanthine-guanine phosphoribosyl transferase deficiency

Drug	Drug Name	Drug Description
DB00437	Allopurinol	A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.

Drug	Drug Name	Target	Type
DB00437	Allopurinol	Xanthine dehydrogenase/oxidase	target
DB00437	Allopurinol	Solute carrier family 22 member 8	transporter
DB00437	Allopurinol	Solute carrier family 22 member 7	transporter
DB00437	Allopurinol	Aldehyde oxidase	enzyme
DB00437	Allopurinol	Xanthine dehydrogenase/oxidase	enzyme
DB00437	Allopurinol	ATP-binding cassette sub-family G member 2	transporter
DB00437	Allopurinol	Solute carrier family 22 member 2	transporter

Drug	Drug Name	Phase	Status	Count
DB12273	Ecopipam	1	Completed	1
DB12273	Ecopipam	3	Terminated	1