Refractory Neuroblastoma

DrugDrug NameDrug Description
DB00853TemozolomideTemozolomide (Temodar and Temodal) is an oral alkylating agent used for the treatment of refractory anaplastic astrocytoma -- a type of cancerous brain tumor. Temozolomide is not active until it is converted at physiologic pH to the active form, 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC).
DB01030TopotecanAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I. [PubChem]
DrugDrug NamePhaseStatusCount
DB09077Dinutuximab1Suspended1
DB00982Isotretinoin1Suspended1
DB00480Lenalidomide1Suspended1
DB00755Tretinoin1Suspended1
DB12147Erdafitinib2Not Yet Recruiting1
DB12147Erdafitinib2Recruiting1
DB12167LY-30234142Recruiting1
DB09074Olaparib2Recruiting2
DB11689Selumetinib2Recruiting1
DB12887Tazemetostat2Recruiting1
DB08881Vemurafenib2Recruiting2
DB13104X-3962Recruiting1