Non Erosive Reflux Disease

Also known as: Nonerosive Reflux Disease / Non-erosive Reflux Esophagitis Disease (NERD) / Non-erosive Reflux Disease(NERD) / Non-erosive Reflux Disease (NERD) / Non-Erosive Reflux Disease / GORD / Gastro-esophageal reflux disease without esophagitis / Gastrooesophageal reflux disease / Gastroesophageal reflux disease / GERD / Gastroesophageal Reflux / Gastroesophageal reflux disease (disorder) / Gastro-esophageal reflux disease

Drug	Drug Name	Drug Description
DB01184	Domperidone	A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
DB01129	Rabeprazole	A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.

Drug	Drug Name	Target	Type
DB01184	Domperidone	Dopamine D2 receptor	target
DB01184	Domperidone	Cytochrome P450 3A4	enzyme
DB01184	Domperidone	Cytochrome P450 3A5	enzyme
DB01184	Domperidone	Cytochrome P450 3A7	enzyme
DB01184	Domperidone	P-glycoprotein 1	transporter
DB01184	Domperidone	Cytochrome P450 1A2	enzyme
DB01184	Domperidone	Cytochrome P450 2B6	enzyme
DB01184	Domperidone	Cytochrome P450 2C8	enzyme
DB01184	Domperidone	Cytochrome P450 2D6	enzyme
DB01184	Domperidone	Dopamine D3 receptor	target
DB01129	Rabeprazole	Potassium-transporting ATPase alpha chain 1	target
DB01129	Rabeprazole	Cytochrome P450 3A4	enzyme
DB01129	Rabeprazole	Cytochrome P450 2C19	enzyme
DB01129	Rabeprazole	ATP-binding cassette sub-family G member 2	transporter
DB01129	Rabeprazole	Cytochrome P450 1A1	enzyme
DB01129	Rabeprazole	Cytochrome P450 1A2	enzyme
DB01129	Rabeprazole	Cytochrome P450 2C9	enzyme
DB01129	Rabeprazole	Cytochrome P450 2D6	enzyme
DB01129	Rabeprazole	Cytochrome P450 2C8	enzyme

Drug	Drug Name	Phase	Status	Count
DB00338	Omeprazole	1 / 2	Unknown Status	1
DB00736	Esomeprazole	2	Completed	1
DB16308	Revaprazan	2	Completed	1
DB00472	Fluoxetine	2 / 3	Completed	1
DB00338	Omeprazole	2 / 3	Completed	1
DB16078	Abeprazan	3	Recruiting	1
DB00736	Esomeprazole	3	Completed	1
DB11964	Ilaprazole	3	Completed	1
DB00338	Omeprazole	3	Completed	2
DB00213	Pantoprazole	3	Unknown Status	1
DB16690	Tegoprazan	3	Completed	2
DB00736	Esomeprazole	4	Completed	1
DB00213	Pantoprazole	4	Terminated	1
DB05351	Dexlansoprazole	Not Available	Unknown Status	1
DB00736	Esomeprazole	Not Available	Completed	1
DB00736	Esomeprazole	Not Available	Terminated	1
DB00448	Lansoprazole	Not Available	Terminated	1
DB00338	Omeprazole	Not Available	Terminated	1
DB00338	Omeprazole	Not Available	Withdrawn	1
DB00213	Pantoprazole	Not Available	Completed	2
DB00213	Pantoprazole	Not Available	Terminated	1
DB01129	Rabeprazole	Not Available	Unknown Status	1
DB00364	Sucralfate	Not Available	Terminated	1
DB00364	Sucralfate	Not Available	Withdrawn	1