Surgical Site Infections

Also known as: SURGICAL SITE INFECTION / Incision site infection / Post-operative wound infection / Postoperative wound infection / Surgical wound infection / Post procedural site wound infection

DrugDrug NameDrug Description
DB01327CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
DB01597CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
DB00303ErtapenemA carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms.
DB00713OxacillinA penicillin antibiotic used to treat a number of susceptible bacterial infections.
DB00319PiperacillinA penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
DB01015SulfamethoxazoleAn sulfonamide antibiotic is used to treat bronchitis, prostatitis, and urinary tract infections.
DB01606TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
DrugDrug NameTargetType
DB01327CefazolinSerum paraoxonase/arylesterase 1target
DB01327CefazolinSerum albumincarrier
DB01327CefazolinSolute carrier family 22 member 6transporter
DB01327CefazolinSolute carrier family 22 member 8transporter
DB01327CefazolinSolute carrier family 22 member 11transporter
DB01327CefazolinPenicillin-binding protein 1Atarget
DB01327CefazolinPenicillin-binding protein 1Btarget
DB01327CefazolinPenicillin-binding protein 2target
DB01327CefazolinPenicillin-binding protein 1Ctarget
DB01327CefazolinPeptidoglycan synthase FtsItarget
DB01327CefazolinMultidrug resistance-associated protein 4transporter
DB01327CefazolinThiopurine S-methyltransferaseenzyme
DB01327CefazolinInterleukin-15target
DB01327CefazolinInterleukin-2target
DB01597CilastatinDipeptidase 1target
DB01597CilastatinSolute carrier family 22 member 6transporter
DB01597CilastatinSolute carrier family 22 member 8transporter
DB00303ErtapenemPenicillin-binding protein 2target
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 1Atarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacCtarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00303ErtapenemPenicillin-binding protein 1Btarget
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 2target
DB00713OxacillinPenicillin-binding protein 1Atarget
DB00713OxacillinSolute carrier family 15 member 1transporter
DB00713OxacillinSolute carrier family 15 member 2transporter
DB00713OxacillinPenicillin-binding protein 3target
DB00713OxacillinPenicillin-binding protein 2atarget
DB00713OxacillinPenicillin-binding protein 1Atarget
DB00713OxacillinPenicillin-binding protein 2Btarget
DB00713OxacillinPenicillin-binding protein 1btarget
DB00713OxacillinSolute carrier family 15 member 1target
DB00713OxacillinPenicillin-binding protein 2target
DB00713OxacillinSolute carrier family 15 member 2target
DB00319PiperacillinSolute carrier family 22 member 6transporter
DB00319PiperacillinPenicillin-binding protein 3target
DB00319PiperacillinPenicillin-binding protein 2Btarget
DB00319PiperacillinPenicillin-binding protein 2atarget
DB00319PiperacillinPenicillin-binding protein 1btarget
DB00319PiperacillinSolute carrier family 22 member 8transporter
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB01015SulfamethoxazoleBile salt export pumptransporter
DB01606TazobactamBeta-lactamase TEMtarget
DB01606TazobactamSolute carrier family 22 member 6transporter
DB01606TazobactamSolute carrier family 22 member 8transporter
DB01606TazobactamBeta-lactamase Ohio-1target
DB01606TazobactamBeta-lactamase SHV-1target
DrugDrug NamePhaseStatusCount
DB01327Cefazolin0Not Yet Recruiting1
DB00898Ethanol0Recruiting1
DB00916Metronidazole0Recruiting1
DB00994Neomycin0Recruiting1
DB11058Petrolatum0Not Yet Recruiting1
DB09287Polyethylene glycol0Recruiting1
DB11077Polyethylene glycol 4000Recruiting1
DB09321Zinc oxide0Not Yet Recruiting1
DB00567Cephalexin1Recruiting1
DB00878Chlorhexidine1Completed2
DB02325Isopropyl alcohol1Completed2
DB00916Metronidazole1Recruiting1
DB00815Sodium lauryl sulfate1Completed1
DB00512Vancomycin1Terminated1
DB09096Benzoyl peroxide2Completed1
DB01112Cefuroxime2Completed1
DB00567Cephalexin2Completed1
DB00878Chlorhexidine2Completed1
DB00878Chlorhexidine2Not Yet Recruiting1
DB00878Chlorhexidine2Recruiting1
DB00878Chlorhexidine2Terminated1
DB01190Clindamycin2Completed1
DB14135Hypochlorous acid2Unknown Status1
DB02325Isopropyl alcohol2Completed1
DB02325Isopropyl alcohol2Not Yet Recruiting1
DB02325Isopropyl alcohol2Terminated1
DB06812Povidone-iodine2Recruiting1
DB06812Povidone-iodine2Terminated1
DB06812Povidone-iodine2Unknown Status1
DB00512Vancomycin2Recruiting1
DB00878Chlorhexidine2 / 3Completed1
DB00668Epinephrine2 / 3Not Yet Recruiting1
DB00303Ertapenem2 / 3Completed1
DB00898Ethanol2 / 3Completed1
DB00281Lidocaine2 / 3Not Yet Recruiting1
DB00916Metronidazole2 / 3Not Yet Recruiting1
DB06812Povidone-iodine2 / 3Completed1
DB01390Sodium bicarbonate2 / 3Not Yet Recruiting1
DB09153Sodium chloride2 / 3Completed1
DB00512Vancomycin2 / 3Enrolling by Invitation1
DB01212Ceftriaxone3Completed1
DB00878Chlorhexidine3Completed3
DB00878Chlorhexidine3Recruiting2
DB06219Dalbavancin3Completed3
DB00080Daptomycin3Completed1
DB11943Delafloxacin3Not Yet Recruiting1
DB00303Ertapenem3Completed1
DB02325Isopropyl alcohol3Completed1
DB02325Isopropyl alcohol3Recruiting1
DB00601Linezolid3Completed2
DB00601Linezolid3Not Yet Recruiting1
DB00916Metronidazole3Completed1
DB00410Mupirocin3Completed1
DB00319Piperacillin3Not Yet Recruiting1
DB12277Polihexanide3Completed1
DB06812Povidone-iodine3Completed1
DB06812Povidone-iodine3Recruiting1
DB01606Tazobactam3Not Yet Recruiting1
DB00560Tigecycline3Not Yet Recruiting1
DB08604Triclosan3Completed1
DB00512Vancomycin3Completed2
DB00512Vancomycin3Not Yet Recruiting1
DB00163Vitamin E3Completed1
DB00163Vitamin E3Recruiting1
DB14003alpha-Tocopherol acetate3Completed1
DB00415Ampicillin4Completed1
DB00626Bacitracin4Recruiting2
DB01327Cefazolin4Not Yet Recruiting1
DB01327Cefazolin4Recruiting2
DB06590Ceftaroline fosamil4Recruiting1
DB01112Cefuroxime4Completed1
DB00567Cephalexin4Not Yet Recruiting1
DB00878Chlorhexidine4Active Not Recruiting1
DB00878Chlorhexidine4Enrolling by Invitation2
DB00878Chlorhexidine4Recruiting2
DB00878Chlorhexidine4Unknown Status1
DB00199Erythromycin4Recruiting1
DB00898Ethanol4Recruiting1
DB05382Iodine4Completed1
DB05382Iodine4Enrolling by Invitation1
DB09537Iodine povacrylex4Recruiting1
DB02325Isopropyl alcohol4Enrolling by Invitation1
DB02325Isopropyl alcohol4Recruiting1
DB02325Isopropyl alcohol4Unknown Status1
DB00410Mupirocin4Active Not Recruiting1
DB00410Mupirocin4Completed1
DB00781Polymyxin B4Recruiting1
DB06812Povidone-iodine4Active Not Recruiting1
DB06812Povidone-iodine4Completed1
DB06812Povidone-iodine4Enrolling by Invitation1
DB06812Povidone-iodine4Not Yet Recruiting1
DB06812Povidone-iodine4Terminated1
DB09324Sulbactam4Completed1
DB00684Tobramycin4Recruiting1
DB08604Triclosan4Recruiting1
DB00512Vancomycin4Completed1
DB00512Vancomycin4Recruiting3
DB01060AmoxicillinNot AvailableCompleted1
DB00207AzithromycinNot AvailableCompleted1
DB00297BupivacaineNot AvailableRecruiting1
DB01327CefazolinNot AvailableCompleted1
DB01327CefazolinNot AvailableRecruiting1
DB00567CephalexinNot AvailableNot Yet Recruiting1
DB00878ChlorhexidineNot AvailableCompleted4
DB00878ChlorhexidineNot AvailableRecruiting1
DB00878ChlorhexidineNot AvailableWithdrawn1
DB00766Clavulanic acidNot AvailableCompleted1
DB00080DaptomycinNot AvailableCompleted1
DB00898EthanolNot AvailableCompleted1
DB00898EthanolNot AvailableWithdrawn1
DB00030Insulin humanNot AvailableCompleted1
DB05382IodineNot AvailableCompleted1
DB02325Isopropyl alcoholNot AvailableCompleted2
DB02325Isopropyl alcoholNot AvailableWithdrawn1
DB00916MetronidazoleNot AvailableNot Yet Recruiting1
DB00916MetronidazoleNot AvailableRecruiting2
DB00410MupirocinNot AvailableCompleted1
DB00410MupirocinNot AvailableRecruiting1
DB00994NeomycinNot AvailableRecruiting1
DB01421ParomomycinNot AvailableRecruiting1
DB11061PovidoneNot AvailableCompleted1
DB06812Povidone-iodineNot AvailableCompleted2
DB06812Povidone-iodineNot AvailableRecruiting1
DB06812Povidone-iodineNot AvailableWithdrawn1
DB00512VancomycinNot AvailableCompleted1
DB00512VancomycinNot AvailableNot Yet Recruiting1
DB00512VancomycinNot AvailableRecruiting1
DB00512VancomycinNot AvailableWithdrawn1