HIV Negative
Also known as: HIV-negative / Human immunodeficiency virus not detected (finding) / HIV test negative
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB08910 | Pomalidomide | A thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma. |
| DB09036 | Siltuximab | An interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB08910 | Pomalidomide | Cytochrome P450 1A2 | enzyme |
| DB08910 | Pomalidomide | Cytochrome P450 3A4 | enzyme |
| DB08910 | Pomalidomide | P-glycoprotein 1 | transporter |
| DB08910 | Pomalidomide | Protein cereblon | target |
| DB08910 | Pomalidomide | Tumor necrosis factor | target |
| DB08910 | Pomalidomide | Prostaglandin G/H synthase 2 | target |
| DB09036 | Siltuximab | Interleukin-6 | target |
| DB09036 | Siltuximab | Cytochrome P450 3A4 | enzyme |