Sickle Cell Crisis

Also known as: Hb-SS disease with crisis, unspecified / Hb-SS disease with crisis / Sickle cell anaemia with crisis / Sickle cell anemia with crisis / Hemoglobin SS disease with crisis (disorder)

Drug	Drug Name	Drug Description
DB01005	Hydroxyurea	An antimetabolite used to treat sickle cell anemia crisis, resistant chronic myeloid leukemia, and Locally advanced squamous cell carcinomas of the head and neck (excluding the lip).

Drug	Drug Name	Target	Type
DB01005	Hydroxyurea	Ribonucleoside-diphosphate reductase large subunit	target
DB01005	Hydroxyurea	Solute carrier organic anion transporter family member 1A2	transporter
DB01005	Hydroxyurea	Solute carrier organic anion transporter family member 1B1	transporter
DB01005	Hydroxyurea	Solute carrier organic anion transporter family member 1B3	transporter
DB01005	Hydroxyurea	Urea transporter 2	transporter
DB01005	Hydroxyurea	Urea transporter 1	transporter
DB01005	Hydroxyurea	Solute carrier family 22 member 4	transporter
DB01005	Hydroxyurea	Solute carrier family 22 member 5	transporter
DB01005	Hydroxyurea	Serum albumin	carrier
DB01005	Hydroxyurea	Urease subunit alpha	enzyme

Drug	Drug Name	Phase	Status	Count
DB00613	Amodiaquine	1 / 2	Completed	1
DB09274	Artesunate	1 / 2	Completed	1
DB00358	Mefloquine	1 / 2	Completed	1
DB01131	Proguanil	1 / 2	Completed	1
DB00205	Pyrimethamine	1 / 2	Completed	1
DB01299	Sulfadoxine	1 / 2	Completed	1
DB00281	Lidocaine	2	Not Yet Recruiting	1
DB00708	Sufentanil	3	Recruiting	1
DB01221	Ketamine	4	Completed	2
DB00295	Morphine	4	Completed	1
DB01221	Ketamine	Not Available	Unknown Status	1
DB00295	Morphine	Not Available	Unknown Status	1