Polyps, Nasal

Also known as: Nasal Polyp / Nasal Polyps / Polyp of nasal cavity NOS / Unspecified nasal polyp / Nasal polyp, unspecified / Polyp of nasal cavity / Polyps nasal

DrugDrug NameDrug Description
DB01222BudesonideBudesonide is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, and allergic rhinitis. [PubChem] The extended release oral tablet, marketed as Uceris, was FDA approved on January 14, 2013 for the management of ulcerative colitis. Budesonide is provided as a mixture of two epimers (22R and 22S). Interestingly, the 22R form is two times more active than the 22S epimer. The two forms do not interconvert.
DB00764MometasoneMometasone is a medium-potency synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Studies in asthmatic patients have demonstrated that mometasone provides a favorable ratio of topical to systemic activity due to its primary local effect along with the extensive hepatic metabolism and the lack of active metabolites. Though effective for the treatment of asthma, glucocorticoids do not affect asthma symptoms immediately. Maximum improvement in symptoms following inhaled administration of mometasone furoate may not be achieved for 1 to 2 weeks or longer after starting treatment. The anti-inflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
DB14512Mometasone furoateMometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
DrugDrug NamePhaseStatusCount
DB00620Triamcinolone1 / 2Terminated1
DB00394Beclomethasone dipropionate2Unknown Status1
DB00588Fluticasone propionate2Enrolling by Invitation1
DB12321Ifetroban2Not Yet Recruiting1
DB00764Mometasone2Enrolling by Invitation1
DB01222Budesonide2 / 3Completed1
DB00620Triamcinolone2 / 3Recruiting1
DB12159Dupilumab3Active Not Recruiting1
DB00588Fluticasone propionate3Completed1
DB06612Mepolizumab3Active Not Recruiting1
DB00764Mometasone3Active Not Recruiting1
DB00043Omalizumab3Active Not Recruiting1
DB00264Metoprolol4Unknown Status1
DB00764Mometasone4Unknown Status1
DB00471Montelukast4Unknown Status1
DB00635Prednisone4Active Not Recruiting1
DB00899Remifentanil4Unknown Status1
DB00193Tramadol4Unknown Status1
DB01222BudesonideNot AvailableCompleted1
DB00588Fluticasone propionateNot AvailableCompleted1
DB00448LansoprazoleNot AvailableCompleted1
DB06602ReslizumabNot AvailableRecruiting1
DB00661VerapamilNot AvailableTerminated1