Peripheral Vascular Disease (PVD)

Also known as: Peripheral vessel disease / PERIPHERAL VASCULAR DISEASES / PERIPHERAL VASCULAR DISEASE / Vasc. dis. periph. NOS / Circulatory disorder peripheral / Intermittent claudication / Peripheral vascular disease NOS / Peripheral vascular disorder / Disorder peripheral vascular / Vascular disorder peripheral / Disorder vascular peripheral / Peripheral vascular disease, unspecified / Peripheral vascular disorder NOS

DrugDrug NameDrug Description
DB00641SimvastatinSimvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus terreus. It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl COA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL receptors, it increases breakdown of LDL cholesterol.