Paroxysmal Atrial Fibrillation (PAF)

Also known as: Paroxysmal Atrial Fibrillation / Fibrillation paroxysmal atrial / Atrial fibrillation paroxysmal / Atrial fibrillation / Auricular fibrillation / Fibrillation atrial / AFib / AF

DrugDrug NameDrug Description
DB04855DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
DB01182PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
DrugDrug NameTargetType
DB04855DronedaroneAlpha-1A adrenergic receptortarget
DB04855DronedaroneBeta-1 adrenergic receptortarget
DB04855DronedaroneAlpha-1B adrenergic receptortarget
DB04855DronedaroneAlpha-1D adrenergic receptortarget
DB04855DronedaroneAlpha-2A adrenergic receptortarget
DB04855DronedaroneAlpha-2B adrenergic receptortarget
DB04855DronedaroneAlpha-2C adrenergic receptortarget
DB04855DronedaronePotassium voltage-gated channel subfamily H member 2target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DB04855DronedaroneCytochrome P450 2D6enzyme
DB04855DronedaroneCytochrome P450 3A4enzyme
DB04855DronedaroneP-glycoprotein 1transporter
DB04855DronedaronePotassium channel subfamily K member 2target
DB04855DronedaroneSerum albumincarrier
DB04855DronedaroneSolute carrier family 22 member 2transporter
DB04855DronedaroneSolute carrier family 22 member 1transporter
DB04855DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DB04855DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DB04855DronedaroneSolute carrier family 22 member 8transporter
DB04855DronedaroneCytochrome P450 3A5enzyme
DB04855DronedaroneCytochrome P450 2J2enzyme
DB04855DronedaroneThyroid hormone receptor alphatarget
DB04855DronedaroneSodium channel protein type 5 subunit alphatarget
DB04855DronedaroneG protein-activated inward rectifier potassium channel 1target
DB04855DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DB04855DronedaroneInward rectifier potassium channeltarget
DB04855DronedaroneSodium/calcium exchanger 1target
DB04855DronedaronePotassium voltage-gated channel subfamily D member 3target
DB01182PropafenoneSodium channel protein type 5 subunit alphatarget
DB01182PropafenonePotassium voltage-gated channel subfamily H member 2target
DB01182PropafenoneCytochrome P450 1A2enzyme
DB01182PropafenoneCytochrome P450 2D6enzyme
DB01182PropafenoneCytochrome P450 3A4enzyme
DB01182PropafenoneP-glycoprotein 1transporter
DB01182PropafenoneBeta-1 adrenergic receptortarget
DB01182PropafenoneBeta-2 adrenergic receptortarget
DrugDrug NamePhaseStatusCount
DB01118Amiodarone2Completed1
DB15047BMS-9193732Terminated1
DB01195Flecainide2Completed1
DB01195Flecainide2Recruiting1
DB01182Propafenone2Completed1
DB00489Sotalol2Completed1
DB01195Flecainide3Completed1
DB01182Propafenone3Completed1
DB00489Sotalol3Completed1
DB01118Amiodarone4Completed1
DB08799Antazoline4Completed1
DB01373Calcium4Completed1
DB13358Cibenzoline4Completed1
DB00204Dofetilide4Completed1
DB04855Dronedarone4Unknown Status1
DB01195Flecainide4Completed1
DB01195Flecainide4Recruiting1
DB01182Propafenone4Completed1
DB00908Quinidine4Completed1
DB01098Rosuvastatin4Not Yet Recruiting1
DB00489Sotalol4Completed1
DB06217Vernakalant4Recruiting1
DB01195FlecainideNot AvailableUnknown Status1
DB12712PilsicainideNot AvailableUnknown Status1
DB01182PropafenoneNot AvailableUnknown Status1