Polycystic Ovaries Syndrome

Also known as: Polycystic Ovary Syndrome / Polycystic Ovary / Polycystic Ovaries / Syndrome, Polycystic Ovary / Sclerocystic ovary syndrome / Stein-Leventhal syndrome / Polycystic ovarian syndrome / Multicystic ovaries

DrugDrug NameDrug Description
DB00331MetforminMetformin is an antihyperglycemic agent of the _biguanide_ class, used for the management of type II diabetes) [FDA label]. Currently, metformin is the first drug of choice for the management of type II diabetes and is prescribed to at least 120 million people worldwide [A176173]. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. Metformin is commonly described as an _insulin sensitizer_ leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels [A176173]. Another well-known benefit of this drug is modest weight loss. Metformin is the drug of choice for obese type II diabetes patients [A36559]. Metformin was first approved in Canada in 1972 [A36552], followed by 1995 in the USA [FDA label]. This drug is available in regular and extended-release forms [FDA label].
DrugDrug NamePhaseStatusCount
DB00097Choriogonadotropin alfa0Completed1
DB00097Choriogonadotropin alfa0Not Yet Recruiting1
DB09126Chorionic Gonadotropin (Human)0Completed1
DB01285Corticotropin0Not Yet Recruiting1
DB04839Cyproterone acetate0Completed1
DB01234Dexamethasone0Withdrawn1
DB00783Estradiol0Recruiting1
DB06785Ganirelix0Completed1
DB00741Hydrocortisone0Withdrawn2
DB11196Inositol0Unknown Status1
DB00007Leuprolide0Withdrawn1
DB00331Metformin0Completed2
DB00331Metformin0Not Yet Recruiting1
DB01132Pioglitazone0Completed1
DB00421Spironolactone0Completed1
DB00421Spironolactone0Recruiting1
DB01284Tetracosactide0Not Yet Recruiting1
DB01284Tetracosactide0Withdrawn1
DB01395Drospirenone1Unknown Status1
DB00977Ethinylestradiol1Unknown Status1
DB00499Flutamide1Recruiting1
DB01167Itraconazole1Terminated1
DB00331Metformin1Completed1
DB00396Progesterone1Recruiting1
DB01399Salsalate1Terminated1
DB00158Folic Acid1 / 2Recruiting1
DB00026Anakinra2Recruiting1
DB01076Atorvastatin2Completed1
DB09126Chorionic Gonadotropin (Human)2Not Yet Recruiting1
DB00882Clomifene2Enrolling by Invitation1
DB00882Clomifene2Not Yet Recruiting1
DB11979Elagolix2Not Yet Recruiting1
DB01276Exenatide2Completed1
DB09024Follitropin2Unknown Status1
DB01006Letrozole2Not Yet Recruiting1
DB00007Leuprolide2Completed1
DB00331Metformin2Completed3
DB00331Metformin2Enrolling by Invitation1
DB00331Metformin2Recruiting1
DB01083Orlistat2Completed1
DB01399Salsalate2Recruiting1
DB00421Spironolactone2Completed1
DB03106scyllo-inositol2Active Not Recruiting1
DB12803Dichloroisoproterenol2 / 3Terminated1
DB09038Empagliflozin2 / 3Completed1
DB00158Folic Acid2 / 3Recruiting1
DB01006Letrozole2 / 3Completed1
DB00331Metformin2 / 3Completed1
DB00331Metformin2 / 3Recruiting1
DB00050Cetrorelix3Completed1
DB00169Cholecalciferol3Completed1
DB00097Choriogonadotropin alfa3Completed1
DB00882Clomifene3Completed4
DB00882Clomifene3Not Yet Recruiting2
DB00882Clomifene3Withdrawn1
DB09066Corifollitropin alfa3Recruiting1
DB06292Dapagliflozin3Recruiting1
DB00304Desogestrel3Recruiting1
DB01395Drospirenone3Completed2
DB01395Drospirenone3Recruiting1
DB00977Ethinylestradiol3Completed2
DB00977Ethinylestradiol3Recruiting1
DB00066Follitropin3Recruiting1
DB01006Letrozole3Completed1
DB01006Letrozole3Not Yet Recruiting1
DB01006Letrozole3Recruiting1
DB06655Liraglutide3Recruiting1
DB00331Metformin3Completed12
DB00331Metformin3Recruiting2
DB00331Metformin3Withdrawn1
DB00191Phentermine3Recruiting1
DB00481Raloxifene3Completed1
DB10982Sage3Not Yet Recruiting1
DB06335Saxagliptin3Completed1
DB00641Simvastatin3Completed1
DB00273Topiramate3Recruiting1
DB06825Triptorelin3Completed1
DB06151Acetylcysteine4Completed1
DB06203Alogliptin4Completed1
DB00169Cholecalciferol4Completed3
DB00882Clomifene4Completed6
DB00882Clomifene4Recruiting1
DB00882Clomifene4Withdrawn1
DB04839Cyproterone acetate4Completed1
DB01395Drospirenone4Completed2
DB01395Drospirenone4Recruiting1
DB00153Ergocalciferol4Recruiting1
DB01175Escitalopram4Completed1
DB00783Estradiol4Completed1
DB00977Ethinylestradiol4Completed3
DB00977Ethinylestradiol4Recruiting1
DB01276Exenatide4Recruiting1
DB00158Folic Acid4Completed1
DB06785Ganirelix4Unknown Status1
DB01006Letrozole4Completed1
DB00007Leuprolide4Terminated1
DB00583Levocarnitine4Completed1
DB11256Levomefolic acid4Completed1
DB06655Liraglutide4Completed1
DB00032Menotropins4Completed1
DB00331Metformin4Active Not Recruiting1
DB00331Metformin4Completed11
DB00331Metformin4Recruiting3
DB00331Metformin4Terminated1
DB00331Metformin4Unknown Status3
DB00331Metformin4Withdrawn1
DB00134Methionine4Completed2
DB09242Moxonidine4Completed1
DB01083Orlistat4Unknown Status1
DB01132Pioglitazone4Completed2
DB01132Pioglitazone4Terminated1
DB00571Propranolol4Completed1
DB00412Rosiglitazone4Completed1
DB01105Sibutramine4Completed1
DB01105Sibutramine4Unknown Status1
DB01261Sitagliptin4Active Not Recruiting1
DB01261Sitagliptin4Completed1
DB06825Triptorelin4Unknown Status1
DB11094Vitamin D4Recruiting1
DB00284AcarboseNot AvailableRecruiting1
DB00284AcarboseNot AvailableSuspended1
DB01076AtorvastatinNot AvailableCompleted1
DB04115BerberineNot AvailableUnknown Status2
DB00169CholecalciferolNot AvailableCompleted1
DB00097Choriogonadotropin alfaNot AvailableCompleted2
DB09126Chorionic Gonadotropin (Human)Not AvailableCompleted1
DB00882ClomifeneNot AvailableCompleted6
DB00882ClomifeneNot AvailableNot Yet Recruiting1
DB00882ClomifeneNot AvailableRecruiting1
DB00882ClomifeneNot AvailableTerminated1
DB01285CorticotropinNot AvailableCompleted1
DB01285CorticotropinNot AvailableRecruiting1
DB04839Cyproterone acetateNot AvailableCompleted1
DB04839Cyproterone acetateNot AvailableRecruiting2
DB01234DexamethasoneNot AvailableCompleted1
DB01234DexamethasoneNot AvailableRecruiting2
DB09341Dextrose, unspecified formNot AvailableCompleted1
DB01395DrospirenoneNot AvailableCompleted2
DB01395DrospirenoneNot AvailableUnknown Status1
DB00783EstradiolNot AvailableActive Not Recruiting2
DB00783EstradiolNot AvailableCompleted1
DB00783EstradiolNot AvailableTerminated1
DB00977EthinylestradiolNot AvailableCompleted2
DB00977EthinylestradiolNot AvailableUnknown Status1
DB01039FenofibrateNot AvailableTerminated1
DB00499FlutamideNot AvailableCompleted1
DB00499FlutamideNot AvailableTerminated2
DB00158Folic AcidNot AvailableCompleted1
DB09024FollitropinNot AvailableCompleted2
DB01006LetrozoleNot AvailableCompleted4
DB01006LetrozoleNot AvailableNot Yet Recruiting1
DB01006LetrozoleNot AvailableUnknown Status2
DB00166Lipoic AcidNot AvailableNot Yet Recruiting1
DB00603Medroxyprogesterone acetateNot AvailableTerminated1
DB01065MelatoninNot AvailableRecruiting1
DB00331MetforminNot AvailableActive Not Recruiting4
DB00331MetforminNot AvailableCompleted14
DB00331MetforminNot AvailableNot Yet Recruiting1
DB00331MetforminNot AvailableRecruiting5
DB00331MetforminNot AvailableTerminated1
DB00331MetforminNot AvailableUnknown Status7
DB01132PioglitazoneNot AvailableTerminated1
DB01132PioglitazoneNot AvailableUnknown Status1
DB00396ProgesteroneNot AvailableActive Not Recruiting2
DB00396ProgesteroneNot AvailableCompleted1
DB00396ProgesteroneNot AvailableTerminated1
DB00412RosiglitazoneNot AvailableSuspended1
DB00641SimvastatinNot AvailableCompleted1
DB00641SimvastatinNot AvailableUnknown Status1
DB00052SomatotropinNot AvailableWithdrawn1
DB00421SpironolactoneNot AvailableCompleted1
DB00421SpironolactoneNot AvailableRecruiting1
DB00624TestosteroneNot AvailableCompleted1
DB01284TetracosactideNot AvailableCompleted1
DB01284TetracosactideNot AvailableRecruiting1
DB09270UbidecarenoneNot AvailableCompleted1
DB03106scyllo-inositolNot AvailableUnknown Status1