Bacterial Infection Due to Helicobacter Pylori (H. Pylori)

Also known as: Helicobacter Pylori Infections / Heliobacter Pylori Infection / H. Pylori Infection / Helicobacter Pylori Infection / H Pylori Infection / Helicobacter infection / Helicobacter Infections

DrugDrug NameDrug Description
DB01060AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
DB09275Bismuth subcitrate potassiumA colloid used for the treatment of peptic ulcer and gastro-esophageal reflux disease (GERD).
DB01294Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
DB00736EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB00448LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB00585NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB00213PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
DB01129RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00615RifabutinAn antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
DB00759TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
DrugDrug NameTargetType
DB01060AmoxicillinPenicillin-binding protein 1Atarget
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter
DB09275Bismuth subcitrate potassiumATP-dependent Clp protease ATP-binding subunit ClpXtarget
DB01294Bismuth subsalicylateSerum albumincarrier
DB01294Bismuth subsalicylateSerotransferrincarrier
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00736EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazoleP-glycoprotein 1transporter
DB00736EsomeprazoleSolute carrier family 22 member 8transporter
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00448LansoprazolePotassium-transporting ATPase alpha chain 1target
DB00448LansoprazoleCytochrome P450 2C19enzyme
DB00448LansoprazoleCytochrome P450 2C9enzyme
DB00448LansoprazoleCytochrome P450 3A4enzyme
DB00448LansoprazoleP-glycoprotein 1transporter
DB00448LansoprazoleATP-binding cassette sub-family G member 2transporter
DB00448LansoprazoleCytochrome P450 1A1enzyme
DB00448LansoprazoleCytochrome P450 1B1enzyme
DB00448LansoprazoleCytochrome P450 2C18enzyme
DB00448LansoprazoleCytochrome P450 2C8enzyme
DB00448LansoprazoleCytochrome P450 2D6enzyme
DB00448LansoprazoleMicrotubule-associated protein tautarget
DB00448LansoprazoleSolute carrier family 22 member 8transporter
DB00448LansoprazoleSolute carrier family 22 member 1transporter
DB00448LansoprazoleSolute carrier family 22 member 2transporter
DB00448LansoprazoleSolute carrier family 22 member 3transporter
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB00585NizatidineHistamine H2 receptortarget
DB00585NizatidineP-glycoprotein 1transporter
DB00585NizatidineCholinesteraseenzyme
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00213PantoprazolePotassium-transporting ATPase alpha chain 1target
DB00213PantoprazoleCytochrome P450 2C19enzyme
DB00213PantoprazoleCytochrome P450 3A4enzyme
DB00213PantoprazoleP-glycoprotein 1transporter
DB00213PantoprazoleATP-binding cassette sub-family G member 2transporter
DB00213PantoprazoleSolute carrier family 22 member 8transporter
DB00213PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB00615RifabutinDNA-directed RNA polymerase subunit alphatarget
DB00615RifabutinHeat shock protein HSP 90-alphatarget
DB00615RifabutinEndoplasmintarget
DB00615RifabutinCytochrome P450 3A4enzyme
DB00615RifabutinDNA-directed RNA polymerase subunit betatarget
DB00615RifabutinDNA-directed RNA polymerase subunit beta'target
DB00615RifabutinCytochrome P450 2C19enzyme
DB00615RifabutinCytochrome P450 2B6enzyme
DB00615RifabutinCytochrome P450 2C8enzyme
DB00615RifabutinCytochrome P450 2C9enzyme
DB00615RifabutinP-glycoprotein 1transporter
DB00759Tetracycline16S ribosomal RNAtarget
DB00759TetracyclineMajor prion proteintarget
DB00759TetracyclineSerum albumincarrier
DB00759TetracyclineCytochrome P450 3A4enzyme
DB00759TetracyclineSolute carrier family 22 member 6transporter
DB00759TetracyclineSolute carrier family 22 member 8transporter
DB00759TetracyclineSolute carrier family 22 member 11transporter
DB00759TetracyclineSolute carrier family 22 member 7transporter
DB00759Tetracycline30S ribosomal protein S3target
DB00759Tetracycline30S ribosomal protein S8target
DB00759Tetracycline30S ribosomal protein S19target
DB00759Tetracycline30S ribosomal protein S14target
DB00759Tetracycline30S ribosomal protein S7target
DB00759TetracyclineMultidrug translocase MdfAtarget
DB00759TetracyclineProtein-arginine deiminase type-4target
DB00759TetracyclineSolute carrier organic anion transporter family member 2B1transporter
DrugDrug NamePhaseStatusCount
DB09147Ferric pyrophosphate1Completed1
DB14491Ferrous fumarate1Completed1
DB01060Amoxicillin1 / 2Completed1
DB01211Clarithromycin1 / 2Completed1
DB00338Omeprazole1 / 2Completed1
DB00819Acetazolamide2Withdrawn1
DB01060Amoxicillin2Withdrawn1
DB01211Clarithromycin2Withdrawn1
DB00736Esomeprazole2Withdrawn1
DB05186SQ-1092Withdrawn1
DB01060Amoxicillin2 / 3Not Yet Recruiting1
DB00338Omeprazole2 / 3Not Yet Recruiting1
DB01060Amoxicillin3Active Not Recruiting1
DB01060Amoxicillin3Completed6
DB01060Amoxicillin3Not Yet Recruiting1
DB01060Amoxicillin3Recruiting3
DB01060Amoxicillin3Unknown Status1
DB09275Bismuth subcitrate potassium3Withdrawn1
DB00169Cholecalciferol3Recruiting1
DB01211Clarithromycin3Active Not Recruiting2
DB01211Clarithromycin3Completed3
DB01211Clarithromycin3Not Yet Recruiting1
DB01211Clarithromycin3Recruiting3
DB00766Clavulanic acid3Recruiting1
DB00736Esomeprazole3Completed2
DB00736Esomeprazole3Recruiting1
DB00736Esomeprazole3Unknown Status1
DB01155Gemifloxacin3Unknown Status1
DB00448Lansoprazole3Completed4
DB00448Lansoprazole3Recruiting1
DB01137Levofloxacin3Completed2
DB01137Levofloxacin3Not Yet Recruiting1
DB00916Metronidazole3Completed1
DB00916Metronidazole3Not Yet Recruiting1
DB00916Metronidazole3Recruiting1
DB00916Metronidazole3Withdrawn1
DB00218Moxifloxacin3Unknown Status1
DB00338Omeprazole3Active Not Recruiting1
DB00338Omeprazole3Completed2
DB00213Pantoprazole3Not Yet Recruiting1
DB01129Rabeprazole3Active Not Recruiting1
DB01129Rabeprazole3Completed1
DB01129Rabeprazole3Recruiting1
DB00615Rifabutin3Completed1
DB00615Rifabutin3Not Yet Recruiting1
DB01220Rifaximin3Completed1
DB00759Tetracycline3Not Yet Recruiting1
DB00759Tetracycline3Recruiting1
DB00759Tetracycline3Withdrawn1
DB00911Tinidazole3Completed1
DB06151Acetylcysteine4Unknown Status2
DB01060Amoxicillin4Active Not Recruiting3
DB01060Amoxicillin4Completed18
DB01060Amoxicillin4Not Yet Recruiting7
DB01060Amoxicillin4Recruiting10
DB01060Amoxicillin4Terminated1
DB01060Amoxicillin4Unknown Status5
DB00126Ascorbic acid4Unknown Status1
DB04115Berberine4Completed1
DB09275Bismuth subcitrate potassium4Unknown Status1
DB01294Bismuth subsalicylate4Active Not Recruiting1
DB01211Clarithromycin4Active Not Recruiting3
DB01211Clarithromycin4Completed14
DB01211Clarithromycin4Not Yet Recruiting5
DB01211Clarithromycin4Recruiting7
DB01211Clarithromycin4Terminated1
DB01211Clarithromycin4Unknown Status3
DB00766Clavulanic acid4Terminated1
DB05351Dexlansoprazole4Completed1
DB00254Doxycycline4Recruiting2
DB00736Esomeprazole4Active Not Recruiting1
DB00736Esomeprazole4Completed8
DB00736Esomeprazole4Not Yet Recruiting1
DB00736Esomeprazole4Recruiting12
DB00614Furazolidone4Completed1
DB00614Furazolidone4Not Yet Recruiting6
DB00614Furazolidone4Recruiting2
DB01592Iron4Recruiting1
DB00448Lansoprazole4Active Not Recruiting1
DB00448Lansoprazole4Completed5
DB00448Lansoprazole4Unknown Status1
DB01137Levofloxacin4Completed5
DB01137Levofloxacin4Not Yet Recruiting4
DB01137Levofloxacin4Recruiting4
DB01137Levofloxacin4Terminated1
DB00916Metronidazole4Active Not Recruiting2
DB00916Metronidazole4Completed12
DB00916Metronidazole4Not Yet Recruiting4
DB00916Metronidazole4Recruiting7
DB00916Metronidazole4Unknown Status4
DB00338Omeprazole4Active Not Recruiting1
DB00338Omeprazole4Completed2
DB00338Omeprazole4Recruiting2
DB00338Omeprazole4Unknown Status1
DB00213Pantoprazole4Completed3
DB11158Pectin4Not Yet Recruiting5
DB11158Pectin4Recruiting1
DB01129Rabeprazole4Active Not Recruiting1
DB01129Rabeprazole4Completed5
DB01129Rabeprazole4Not Yet Recruiting4
DB01129Rabeprazole4Recruiting4
DB01129Rabeprazole4Terminated1
DB01129Rabeprazole4Unknown Status2
DB00615Rifabutin4Recruiting1
DB00759Tetracycline4Active Not Recruiting1
DB00759Tetracycline4Completed2
DB00759Tetracycline4Not Yet Recruiting6
DB00759Tetracycline4Recruiting4
DB00759Tetracycline4Unknown Status1
DB00911Tinidazole4Completed1
DB00911Tinidazole4Not Yet Recruiting4
DB00911Tinidazole4Recruiting1
DB11739Vonoprazan4Recruiting1
DB01060AmoxicillinNot AvailableCompleted15
DB01060AmoxicillinNot AvailableEnrolling by Invitation1
DB01060AmoxicillinNot AvailableRecruiting5
DB09275Bismuth subcitrate potassiumNot AvailableTerminated1
DB04272Citric acidNot AvailableCompleted1
DB01211ClarithromycinNot AvailableCompleted13
DB01211ClarithromycinNot AvailableRecruiting4
DB05351DexlansoprazoleNot AvailableCompleted1
DB05351DexlansoprazoleNot AvailableRecruiting1
DB00736EsomeprazoleNot AvailableCompleted6
DB00736EsomeprazoleNot AvailableRecruiting2
DB01592IronNot AvailableCompleted1
DB01137LevofloxacinNot AvailableCompleted3
DB01137LevofloxacinNot AvailableRecruiting2
DB00916MetronidazoleNot AvailableCompleted10
DB00916MetronidazoleNot AvailableRecruiting2
DB00916MetronidazoleNot AvailableTerminated1
DB00338OmeprazoleNot AvailableCompleted3
DB00213PantoprazoleNot AvailableCompleted4
DB00213PantoprazoleNot AvailableRecruiting1
DB00213PantoprazoleNot AvailableTerminated1
DB01129RabeprazoleNot AvailableEnrolling by Invitation1
DB01129RabeprazoleNot AvailableRecruiting1
DB00759TetracyclineNot AvailableCompleted6
DB00759TetracyclineNot AvailableRecruiting2
DB00759TetracyclineNot AvailableTerminated1