Pain, Chronic

Also known as: Chronic Pain / Pain NOS / Pain finding / Acute pain NOS / Pain

DrugDrug NameDrug Description
DB00345Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
DB00182AmphetamineA CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
DB01151DesipramineA tricyclic antidepressant used in the treatment of depression.
DB00295MorphineAn opioid agonist used for the relief of moderate to severe acute and chronic pain.
DB00540NortriptylineA tricyclic antidepressant used in the treatment of depression.
DrugDrug NameTargetType
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00182AmphetamineSodium-dependent dopamine transportertarget
DB00182AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
DB00182AmphetamineTrace amine-associated receptor 1target
DB00182AmphetamineCytochrome P450 2D6enzyme
DB00182AmphetamineSolute carrier family 22 member 3transporter
DB00182AmphetamineSolute carrier family 22 member 5transporter
DB00182AmphetamineSynaptic vesicular amine transportertarget
DB00182AmphetamineCytochrome P450 2A6enzyme
DB00182AmphetamineSodium-dependent noradrenaline transportertarget
DB00182AmphetamineAlpha adrenergic receptortarget
DB00182AmphetamineBeta adrenergic receptortarget
DB00182AmphetamineDopamine D2 receptortarget
DB00182AmphetamineAmine oxidase [flavin-containing] Btarget
DB00182AmphetamineSodium-dependent serotonin transportertarget
DB00182AmphetamineMonoamine oxidasetarget
DB00182Amphetaminevesicular monoamine transporter 2 (VMAT2)target
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineP-glycoprotein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineDopamine D2 receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB00295MorphineMu-type opioid receptortarget
DB00295MorphineDelta-type opioid receptortarget
DB00295MorphineKappa-type opioid receptortarget
DB00295MorphineP-glycoprotein 1transporter
DB00295MorphineCytochrome P450 2C8enzyme
DB00295MorphineCytochrome P450 3A4enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B7enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-1enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-8enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B15enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B4enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-3enzyme
DB00295MorphineLymphocyte antigen 96target
DB00295MorphineSerum albumincarrier
DB00540NortriptylineSodium-dependent serotonin transportertarget
DB00540NortriptylineSodium-dependent noradrenaline transportertarget
DB00540NortriptylineCytochrome P450 1A2enzyme
DB00540NortriptylineCytochrome P450 2D6enzyme
DB00540NortriptylineSerum albumincarrier
DB00540NortriptylineAlpha-1-acid glycoprotein 1carrier
DB00540NortriptylineHistamine H1 receptortarget
DB00540NortriptylineMuscarinic acetylcholine receptor M1target
DB00540NortriptylineMuscarinic acetylcholine receptor M2target
DB00540NortriptylineMuscarinic acetylcholine receptor M3target
DB00540NortriptylineMuscarinic acetylcholine receptor M4target
DB00540NortriptylineMuscarinic acetylcholine receptor M5target
DB00540Nortriptyline5-hydroxytryptamine receptor 2Atarget
DB00540NortriptylineAlpha-1A adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Atarget
DB00540NortriptylineCytochrome P450 3A4enzyme
DB00540NortriptylineCytochrome P450 3A5enzyme
DB00540NortriptylineAlpha-1D adrenergic receptortarget
DB00540NortriptylineCytochrome P450 2C19enzyme
DB00540NortriptylineProstaglandin G/H synthase 1enzyme
DB00540NortriptylineCytochrome P450 2E1enzyme
DB00540Nortriptyline5-hydroxytryptamine receptor 2Ctarget
DB00540Nortriptyline5-hydroxytryptamine receptor 6target
DB00540NortriptylineAlpha-1B adrenergic receptortarget
DB00540NortriptylineAlpha-2 adrenergic receptorstarget
DB00540NortriptylineBeta adrenergic receptortarget
DB00540NortriptylineDopamine D2 receptortarget
DB00540NortriptylineSigma receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Ctarget
DrugDrug NamePhaseStatusCount
DB09061Cannabidiol0Not Yet Recruiting1
DB00413Pramipexole0Recruiting1
DB15377ATB-3461Completed1
DB15333AZD-13861Completed2
DB00316Acetaminophen1Completed1
DB00921Buprenorphine1Completed1
DB00921Buprenorphine1Recruiting1
DB00490Buspirone1Recruiting1
DB00201Caffeine1Completed1
DB09061Cannabidiol1Withdrawn1
DB00586Diclofenac1Not Yet Recruiting1
DB00470Dronabinol1Withdrawn1
DB00327Hydromorphone1Completed1
DB01221Ketamine1Completed1
DB01221Ketamine1Recruiting1
DB00281Lidocaine1Completed1
DB00653Magnesium sulfate1Recruiting1
DB14009Medical Cannabis1Withdrawn1
DB00683Midazolam1Completed1
DB00295Morphine1Completed1
DB00295Morphine1Recruiting1
DB01183Naloxone1Completed2
DB00704Naltrexone1Completed1
DB00704Naltrexone1Recruiting1
DB00338Omeprazole1Completed1
DB00497Oxycodone1Completed5
DB12012PF-044578451Completed1
DB12468Pf-045310831Completed2
DB00641Simvastatin1Completed1
DB01124Tolbutamide1Completed1
DB01273Varenicline1Completed1
DB00921Buprenorphine1 / 2Unknown Status1
DB00633Dexmedetomidine1 / 2Active Not Recruiting1
DB00813Fentanyl1 / 2Completed1
DB01221Ketamine1 / 2Completed1
DB00281Lidocaine1 / 2Recruiting1
DB00295Morphine1 / 2Active Not Recruiting1
DB00624Testosterone1 / 2Unknown Status1
DB00819Acetazolamide2Withdrawn1
DB12139Alisporivir2Completed1
DB00297Bupivacaine2Terminated1
DB00921Buprenorphine2Active Not Recruiting1
DB00921Buprenorphine2Enrolling by Invitation1
DB00921Buprenorphine2Unknown Status1
DB09061Cannabidiol2Not Yet Recruiting1
DB12830Cebranopadol2Completed1
DB00470Dronabinol2Completed2
DB00470Dronabinol2Recruiting1
DB12177Eplivanserin2Completed1
DB00813Fentanyl2Completed1
DB00996Gabapentin2Not Yet Recruiting2
DB00996Gabapentin2Terminated1
DB08872Gabapentin enacarbil2Terminated1
DB01221Ketamine2Recruiting1
DB01221Ketamine2Terminated1
DB00281Lidocaine2Terminated1
DB14009Medical Cannabis2Recruiting2
DB00379Mexiletine2Completed1
DB01017Minocycline2Completed1
DB01017Minocycline2Recruiting1
DB00295Morphine2Completed2
DB00295Morphine2Not Yet Recruiting1
DB00295Morphine2Withdrawn1
DB01183Naloxone2Completed1
DB01183Naloxone2Enrolling by Invitation1
DB01183Naloxone2Unknown Status1
DB00704Naltrexone2Completed1
DB00704Naltrexone2Not Yet Recruiting1
DB00008Peginterferon alfa-2a2Completed1
DB00230Pregabalin2Completed1
DB00230Pregabalin2Terminated1
DB00230Pregabalin2Unknown Status1
DB00468Quinine2Withdrawn1
DB00811Ribavirin2Completed1
DB00140Riboflavin2Withdrawn1
DB00708Sufentanil2Withdrawn1
DB06204Tapentadol2Completed1
DB00470Dronabinol2 / 3Completed1
DB01221Ketamine2 / 3Recruiting1
DB00107Oxytocin2 / 3Not Yet Recruiting1
DB00316Acetaminophen3Completed1
DB00297Bupivacaine3Completed2
DB00921Buprenorphine3Active Not Recruiting1
DB00921Buprenorphine3Completed2
DB14012Burosumab3Active Not Recruiting1
DB12830Cebranopadol3Completed1
DB12830Cebranopadol3Terminated1
DB00482Celecoxib3Completed1
DB00813Fentanyl3Completed8
DB00813Fentanyl3Terminated1
DB00813Fentanyl3Withdrawn1
DB00996Gabapentin3Recruiting1
DB00996Gabapentin3Terminated1
DB00956Hydrocodone3Completed2
DB00327Hydromorphone3Completed2
DB00327Hydromorphone3Terminated1
DB01221Ketamine3Active Not Recruiting2
DB01221Ketamine3Recruiting1
DB01221Ketamine3Withdrawn1
DB00281Lidocaine3Active Not Recruiting1
DB00281Lidocaine3Completed1
DB00281Lidocaine3Recruiting1
DB14146Loxicodegol3Completed2
DB00683Midazolam3Recruiting1
DB00295Morphine3Completed2
DB00295Morphine3Terminated1
DB00704Naltrexone3Completed2
DB00497Oxycodone3Completed4
DB01192Oxymorphone3Completed3
DB01192Oxymorphone3Terminated1
DB01192Oxymorphone3Withdrawn1
DB00635Prednisone3Recruiting1
DB00230Pregabalin3Completed1
DB00230Pregabalin3Withdrawn1
DB09153Sodium chloride3Active Not Recruiting1
DB09153Sodium chloride3Completed1
DB09153Sodium chloride3Recruiting1
DB12335Tanezumab3Completed1
DB06204Tapentadol3Completed2
DB06204Tapentadol3Terminated3
DB00193Tramadol3Completed7
DB00193Tramadol3Terminated1
DB00316Acetaminophen4Completed4
DB00316Acetaminophen4Withdrawn1
DB00321Amitriptyline4Completed2
DB00443Betamethasone4Recruiting1
DB00297Bupivacaine4Active Not Recruiting1
DB00297Bupivacaine4Completed1
DB00921Buprenorphine4Suspended1
DB00318Codeine4Withdrawn1
DB01151Desipramine4Recruiting1
DB01234Dexamethasone4Completed1
DB01234Dexamethasone4Recruiting3
DB14649Dexamethasone acetate4Completed1
DB00633Dexmedetomidine4Completed1
DB00633Dexmedetomidine4Recruiting1
DB00476Duloxetine4Completed1
DB00476Duloxetine4Enrolling by Invitation1
DB00476Duloxetine4Not Yet Recruiting1
DB00476Duloxetine4Recruiting1
DB11823Esketamine4Completed1
DB00977Ethinylestradiol4Recruiting1
DB12728Fenpropidin4Recruiting1
DB00813Fentanyl4Completed7
DB00813Fentanyl4Recruiting1
DB00813Fentanyl4Suspended1
DB04841Flunarizine4Recruiting1
DB00996Gabapentin4Completed1
DB01018Guanfacine4Recruiting1
DB08818Hyaluronic acid4Not Yet Recruiting1
DB00956Hydrocodone4Completed2
DB00327Hydromorphone4Completed1
DB00327Hydromorphone4Recruiting1
DB01221Ketamine4Active Not Recruiting2
DB01221Ketamine4Completed1
DB01221Ketamine4Recruiting1
DB01002Levobupivacaine4Recruiting1
DB00281Lidocaine4Completed1
DB00281Lidocaine4Recruiting1
DB00281Lidocaine4Terminated1
DB00333Methadone4Completed3
DB00959Methylprednisolone4Recruiting1
DB04896Milnacipran4Completed1
DB00295Morphine4Completed6
DB00295Morphine4Recruiting4
DB00295Morphine4Suspended1
DB00295Morphine4Terminated1
DB01183Naloxone4Completed1
DB01183Naloxone4Recruiting1
DB01183Naloxone4Withdrawn1
DB00704Naltrexone4Terminated1
DB00717Norethisterone4Recruiting1
DB00904Ondansetron4Completed1
DB00497Oxycodone4Completed2
DB00497Oxycodone4Recruiting3
DB00497Oxycodone4Suspended1
DB00497Oxycodone4Terminated2
DB00497Oxycodone4Withdrawn1
DB01192Oxymorphone4Completed1
DB00107Oxytocin4Recruiting2
DB14043Palmidrol4Completed1
DB03255Phenol4Recruiting1
DB00230Pregabalin4Completed1
DB00230Pregabalin4Recruiting1
DB00818Propofol4Active Not Recruiting1
DB00899Remifentanil4Active Not Recruiting1
DB00899Remifentanil4Completed2
DB00296Ropivacaine4Recruiting1
DB01236Sevoflurane4Active Not Recruiting1
DB09153Sodium chloride4Completed2
DB00708Sufentanil4Completed1
DB01036Tolterodine4Completed2
DB00193Tramadol4Completed1
DB00656Trazodone4Recruiting1
DB00316AcetaminophenNot AvailableCompleted1
DB00921BuprenorphineNot AvailableRecruiting1
DB00260CycloserineNot AvailableRecruiting1
DB01234DexamethasoneNot AvailableRecruiting1
DB01075DiphenhydramineNot AvailableTerminated1
DB00813FentanylNot AvailableActive Not Recruiting1
DB00813FentanylNot AvailableCompleted1
DB00996GabapentinNot AvailableRecruiting1
DB01018GuanfacineNot AvailableRecruiting1
DB01050IbuprofenNot AvailableTerminated1
DB01221KetamineNot AvailableCompleted2
DB01221KetamineNot AvailableUnknown Status1
DB00465KetorolacNot AvailableCompleted1
DB00854LevorphanolNot AvailableCompleted1
DB00281LidocaineNot AvailableNot Yet Recruiting2
DB14009Medical CannabisNot AvailableNot Yet Recruiting1
DB14009Medical CannabisNot AvailableRecruiting1
DB00333MethadoneNot AvailableUnknown Status1
DB00959MethylprednisoloneNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB04896MilnacipranNot AvailableRecruiting1
DB00295MorphineNot AvailableActive Not Recruiting1
DB00295MorphineNot AvailableCompleted2
DB01183NaloxoneNot AvailableActive Not Recruiting1
DB12510OzoneNot AvailableCompleted1
DB12510OzoneNot AvailableRecruiting1
DB03255PhenolNot AvailableRecruiting1
DB00899RemifentanilNot AvailableCompleted1
DB00296RopivacaineNot AvailableCompleted1
DB00193TramadolNot AvailableTerminated1