Phenylketonuria (PKU)

Also known as: PKU / Phenylketonuria / Phenylketonurias / Phenylalaninaemia / Phenylalaninemia / Phenylketouria

DrugDrug NameDrug Description
DB00360SapropterinSapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
DrugDrug NamePhaseStatusCount
DB00218Moxifloxacin1Completed1
DB12839Pegvaliase1Completed1
DB00360Sapropterin1Completed1
DB00360Sapropterin1Unknown Status1
DB12839Pegvaliase2Completed4
DB00360Sapropterin2Completed1
DB00360Sapropterin2Terminated2
DB09255Dextran3Active Not Recruiting1
DB12839Pegvaliase3Active Not Recruiting2
DB12839Pegvaliase3Completed1
DB00360Sapropterin3Active Not Recruiting1
DB00360Sapropterin3Completed4
DB00360Sapropterin4Active Not Recruiting1
DB00360Sapropterin4Completed2
DB00360Sapropterin4Recruiting1
DB00360SapropterinNot AvailableApproved for Marketing1
DB00360SapropterinNot AvailableCompleted5
DB00360SapropterinNot AvailableRecruiting1
DB00360SapropterinNot AvailableTerminated3
DB00360SapropterinNot AvailableUnknown Status1
DB00360SapropterinNot AvailableWithdrawn1