Otitis Media (OM)

Also known as: Otitis Media / Ear infection / Otitis media NOS / Middle ear infection / Unspecified otitis media / Middle ear inflammation / Catarrh of middle ear

DrugDrug NameDrug Description
DB01416CefpodoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
DB00567CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB01211ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
DB00766Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
DB01190ClindamycinAn antibiotic used to treat serious infections caused by susceptible anaerobic bacteria, such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, and dental infections.
DB01015SulfamethoxazoleAn sulfonamide antibiotic is used to treat bronchitis, prostatitis, and urinary tract infections.
DrugDrug NameTargetType
DB01416CefpodoximePeptidoglycan synthase FtsItarget
DB00567CephalexinSerum albumincarrier
DB00567CephalexinSolute carrier family 22 member 5transporter
DB00567CephalexinSolute carrier family 15 member 1transporter
DB00567CephalexinSolute carrier family 15 member 2transporter
DB00567CephalexinSolute carrier family 22 member 6transporter
DB00567CephalexinSolute carrier family 22 member 8transporter
DB00567CephalexinMultidrug and toxin extrusion protein 1transporter
DB00567CephalexinPenicillin-binding protein 3target
DB00567CephalexinPenicillin-binding protein 2atarget
DB00567CephalexinPenicillin-binding protein 1btarget
DB00567CephalexinPenicillin-binding protein 1Atarget
DB00567CephalexinPenicillin-binding protein 2Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinP-glycoprotein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01211ClarithromycinBile salt export pumptransporter
DB00766Clavulanic acidBacterial beta-lactamase enzymesenzyme
DB00766Clavulanic acidBacterial beta-lactamase enzymestarget
DB00766Clavulanic acidSodium/glucose cotransporter 1transporter
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S ribosomal RNAtarget
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB01015SulfamethoxazoleBile salt export pumptransporter
DrugDrug NamePhaseStatusCount
DB11129Carbamide peroxide1Recruiting1
DB09047Finafloxacin1Withdrawn1
DB11774Pazufloxacin1Recruiting1
DB01234Dexamethasone1 / 2Active Not Recruiting1
DB00319Piperacillin1 / 2Active Not Recruiting1
DB01606Tazobactam1 / 2Active Not Recruiting1
DB01086Benzocaine2Completed1
DB05659Faropenem medoxomil2Completed1
DB09512Simethicone2Completed1
DB01060Amoxicillin3Completed1
DB00207Azithromycin3Completed1
DB00537Ciprofloxacin3Completed1
DB01211Clarithromycin3Completed1
DB00766Clavulanic acid3Completed1
DB01137Levofloxacin3Completed2
DB01165Ofloxacin3Completed1
DB00976Telithromycin3Completed1
DB00976Telithromycin3Terminated1
DB06151Acetylcysteine4Withdrawn1
DB01060Amoxicillin4Completed1
DB00537Ciprofloxacin4Withdrawn1
DB01234Dexamethasone4Withdrawn1
DB00003Dornase alfa4Completed1
DB00813Fentanyl4Completed1
DB00813Fentanyl4Recruiting1
DB00465Ketorolac4Recruiting1
DB00471Montelukast4Completed1
DB00295Morphine4Completed1
DB01165Ofloxacin4Not Yet Recruiting1
DB11129Carbamide peroxideNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableUnknown Status1