Dementias

Also known as: Dementia / Dementia NOS / Amentia

DrugDrug NameDrug Description
DB00674GalantamineA benzazepine derived from norbelladine. It is found in galanthus and other amaryllidaceae. Galantamine is a cholinesterase inhibitor that has been used to reverse the muscular effects of gallamine triethiodide and tubocurarine, and has been studied as a treatment for Alzheimer's disease and other central nervous system disorders.
DB00831TrifluoperazineA phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic. [PubChem]
DrugDrug NameTargetType
DB00674GalantamineCytochrome P450 3A4enzyme
DB00674GalantamineCytochrome P450 2D6enzyme
DB00674GalantamineAcetylcholinesterasetarget
DB00674GalantamineAcetylcholine receptor subunit alphatarget
DB00674GalantamineAcetylcholine receptor subunit betatarget
DB00674GalantamineAcetylcholine receptor subunit deltatarget
DB00674GalantamineAcetylcholine receptor subunit gammatarget
DB00674GalantamineAcetylcholine receptor subunit epsilontarget
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-4target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-5target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-6target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-7target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-9target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-10target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-4target
DB00674GalantamineCholinesterasetarget
DB00831TrifluoperazineD(2) dopamine receptortarget
DB00831TrifluoperazineAlpha-1A adrenergic receptortarget
DB00831TrifluoperazineNeuron-specific vesicular protein calcyontarget
DB00831TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
DB00831TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
DB00831TrifluoperazineCytochrome P450 1A2enzyme
DB00831TrifluoperazineMultidrug resistance protein 1transporter
DB00831TrifluoperazineCalmodulintarget
DB00831TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
DB00831TrifluoperazineProtein S100-A4target
DrugDrug NamePhaseStatusCount
DB00747Scopolamine0Recruiting1
DB06616Bosutinib1Enrolling by Invitation1
DB00843Donepezil1Completed2
DB00843Donepezil1Terminated1
DB06655Liraglutide1Completed1
DB00186Lorazepam1Completed1
DB11910MK-02491Terminated1
DB00747Scopolamine1Completed1
DB01104Sertraline1Completed1
DB00313Valproic Acid1Unknown Status1
DB00316Acetaminophen2Completed1
DB00083Botulinum Toxin Type A2Completed1
DB06247CX5162Completed1
DB00215Citalopram2Completed1
DB00470Dronabinol2Completed1
DB11726Encenicline2Withdrawn1
DB14009Medical Cannabis2Completed1
DB01043Memantine2Completed1
DB00331Metformin2Completed1
DB12969Methylinositol2Completed2
DB04870Oleoyl-estrone2Recruiting1
DB01367Rasagiline2Completed1
DB00734Risperidone2Completed1
DB00989Rivastigmine2Unknown Status1
DB01656Roflumilast2Completed1
DB09153Sodium Chloride2Completed1
DB00316Acetaminophen2 / 3Completed1
DB00351Megestrol acetate2 / 3Terminated1
DB00295Morphine2 / 3Completed1
DB00230Pregabalin2 / 3Completed1
DB11756Solanezumab2 / 3Active Not Recruiting1
DB00659Acamprosate3Terminated1
DB06594Agomelatine3Terminated1
DB00404Alprazolam3Terminated1
DB06288Amisulpride3Terminated1
DB00321Amitriptyline3Terminated1
DB01238Aripiprazole3Completed1
DB01238Aripiprazole3Terminated1
DB00810Biperiden3Terminated1
DB01558Bromazepam3Terminated1
DB09017Brotizolam3Terminated1
DB01156Bupropion3Terminated1
DB00490Buspirone3Terminated1
DB00564Carbamazepine3Recruiting1
DB00564Carbamazepine3Terminated1
DB01563Chloral hydrate3Terminated1
DB01239Chlorprothixene3Terminated1
DB00215Citalopram3Completed1
DB00215Citalopram3Terminated1
DB00349Clobazam3Terminated1
DB01242Clomipramine3Terminated1
DB01068Clonazepam3Terminated1
DB00363Clozapine3Terminated1
DB00829Diazepam3Terminated1
DB01075Diphenhydramine3Terminated1
DB00843Donepezil3Completed2
DB00843Donepezil3Terminated1
DB01142Doxepin3Terminated1
DB00476Duloxetine3Terminated1
DB11726Encenicline3Terminated3
DB01175Escitalopram3Recruiting1
DB01175Escitalopram3Terminated1
DB00472Fluoxetine3Terminated1
DB00875Flupentixol3Terminated1
DB00623Fluphenazine3Terminated1
DB00690Flurazepam3Terminated1
DB04842Fluspirilene3Terminated1
DB00176Fluvoxamine3Terminated1
DB00996Gabapentin3Terminated1
DB00674Galantamine3Completed10
DB00674Galantamine3Terminated1
DB01381Ginkgo biloba3Completed1
DB00502Haloperidol3Terminated1
DB00557Hydroxyzine3Terminated1
DB00458Imipramine3Terminated1
DB06218Lacosamide3Terminated1
DB00555Lamotrigine3Terminated1
DB01202Levetiracetam3Terminated1
DB01356Lithium cation3Terminated1
DB00186Lorazepam3Terminated1
DB00934Maprotiline3Terminated1
DB01065Melatonin3Terminated1
DB09224Melperone3Terminated1
DB01043Memantine3Terminated1
DB01403Methotrimeprazine3Terminated1
DB06148Mianserin3Terminated1
DB00683Midazolam3Terminated1
DB00370Mirtazapine3Recruiting1
DB00370Mirtazapine3Terminated1
DB01171Moclobemide3Terminated1
DB00699Nicergoline3Terminated1
DB01595Nitrazepam3Terminated1
DB00540Nortriptyline3Terminated1
DB00334Olanzapine3Terminated1
DB00842Oxazepam3Terminated1
DB00776Oxcarbazepine3Terminated1
DB01267Paliperidone3Terminated1
DB00715Paroxetine3Terminated1
DB00850Perphenazine3Completed1
DB00850Perphenazine3Terminated1
DB01174Phenobarbital3Terminated1
DB00252Phenytoin3Terminated1
DB01100Pimozide3Terminated1
DB09286Pipamperone3Terminated1
DB09210Piracetam3Terminated1
DB00230Pregabalin3Terminated1
DB01069Promethazine3Terminated1
DB01224Quetiapine3Terminated2
DB00234Reboxetine3Terminated1
DB00734Risperidone3Completed4
DB00734Risperidone3Terminated2
DB00989Rivastigmine3Completed1
DB00989Rivastigmine3Terminated1
DB06144Sertindole3Terminated1
DB01104Sertraline3Terminated1
DB00391Sulpiride3Terminated1
DB05289Tarenflurbil3Completed1
DB05289Tarenflurbil3Terminated1
DB00231Temazepam3Terminated1
DB00679Thioridazine3Terminated1
DB13025Tiapride3Terminated1
DB00273Topiramate3Terminated1
DB00752Tranylcypromine3Terminated1
DB00656Trazodone3Terminated1
DB00897Triazolam3Terminated1
DB00726Trimipramine3Terminated1
DB00313Valproic Acid3Terminated2
DB00285Venlafaxine3Terminated1
DB00962Zaleplon3Terminated1
DB01593Zinc3Terminated1
DB00246Ziprasidone3Terminated1
DB00425Zolpidem3Terminated1
DB01198Zopiclone3Terminated1
DB01624Zuclopenthixol3Terminated1
DB06470clomethiazole3Terminated1
DB00316Acetaminophen4Completed1
DB00316Acetaminophen4Unknown Status1
DB00945Acetylsalicylic acid4Active Not Recruiting1
DB00915Amantadine4Terminated1
DB01238Aripiprazole4Completed1
DB00921Buprenorphine4Unknown Status1
DB00215Citalopram4Completed2
DB06695Dabigatran etexilate4Recruiting1
DB01576Dextroamphetamine4Completed1
DB00514Dextromethorphan4Unknown Status1
DB00843Donepezil4Completed2
DB00843Donepezil4Unknown Status1
DB00476Duloxetine4Completed1
DB00625Efavirenz4Completed1
DB01175Escitalopram4Completed3
DB00674Galantamine4Completed3
DB01381Ginkgo biloba4Completed1
DB04864Huperzine A4Unknown Status1
DB05510Huperzine A4Unknown Status1
DB00956Hydrocodone4Completed1
DB08824Ioflupane I-1234Enrolling by Invitation1
DB01221Ketamine4Recruiting1
DB00709Lamivudine4Completed1
DB01065Melatonin4Completed1
DB01043Memantine4Completed1
DB01043Memantine4Unknown Status2
DB00422Methylphenidate4Completed3
DB00422Methylphenidate4Terminated1
DB00422Methylphenidate4Unknown Status1
DB00238Nevirapine4Completed1
DB00699Nicergoline4Completed1
DB00393Nimodipine4Completed1
DB00334Olanzapine4Completed3
DB00715Paroxetine4Completed1
DB09210Piracetam4Completed1
DB00457Prazosin4Recruiting1
DB00818Propofol4Recruiting1
DB01224Quetiapine4Completed2
DB01224Quetiapine4Withdrawn1
DB00908Quinidine4Unknown Status1
DB00734Risperidone4Completed4
DB01104Sertraline4Completed1
DB01236Sevoflurane4Recruiting1
DB00300Tenofovir disoproxil4Completed1
DB00313Valproic Acid4Completed1
DB00313Valproic Acid4Withdrawn1
DB00285Venlafaxine4Completed1
DB00682Warfarin4Recruiting1
DB00495Zidovudine4Completed1
DB00482CelecoxibNot AvailableCompleted1
DB01189DesfluraneNot AvailableCompleted1
DB00843DonepezilNot AvailableCompleted3
DB00843DonepezilNot AvailableTerminated1
DB09151Flutemetamol (18F)Not AvailableRecruiting1
DB00996GabapentinNot AvailableCompleted1
DB00674GalantamineNot AvailableCompleted1
DB00674GalantamineNot AvailableTerminated1
DB14566Lavender oilNot AvailableActive Not Recruiting1
DB01043MemantineNot AvailableCompleted2
DB01043MemantineNot AvailableUnknown Status1
DB00370MirtazapineNot AvailableCompleted1
DB00818PropofolNot AvailableCompleted2
DB01224QuetiapineNot AvailableCompleted1
DB00734RisperidoneNot AvailableCompleted1
DB00989RivastigmineNot AvailableTerminated1
DB06140SUVN-502Not AvailableAvailable1
DB01236SevofluraneNot AvailableCompleted1
DB00425ZolpidemNot AvailableCompleted1