Hepatitis B Chronic Infection

Also known as: Hepatitis B, Chronic / Chronic Hepatitis B Infection / Chronic Hepatitis B / HEPATITIS B CHRONIC / Hepatitis B,Chronic / Chronic (viral) hepatitis B / Chronic viral hepatitis B

DrugDrug NameDrug Description
DB00718Adefovir dipivoxilA nucleotide analog used to treat chronic hepatitis B.
DB00442EntecavirA nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
DB00709LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
DB00008Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB01265TelbivudineA thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
DB09299Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
DB00300Tenofovir disoproxilA nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
DrugDrug NameTargetType
DB00718Adefovir dipivoxilDNA polymerase/reverse transcriptasetarget
DB00718Adefovir dipivoxilSolute carrier family 22 member 6transporter
DB00718Adefovir dipivoxilMultidrug resistance-associated protein 4transporter
DB00718Adefovir dipivoxilMultidrug resistance-associated protein 5transporter
DB00718Adefovir dipivoxilSolute carrier family 22 member 3transporter
DB00718Adefovir dipivoxilAdenylate kinase 2, mitochondrialenzyme
DB00718Adefovir dipivoxilAdenylate kinase 4, mitochondrialenzyme
DB00718Adefovir dipivoxilNucleoside diphosphate kinase Aenzyme
DB00718Adefovir dipivoxilNucleoside diphosphate kinase Benzyme
DB00442EntecavirDNAtarget
DB00709LamivudineDNAtarget
DB00709LamivudineProtein Ptarget
DB00709LamivudineMultidrug resistance-associated protein 1transporter
DB00709LamivudineSolute carrier family 22 member 6transporter
DB00709LamivudineATP-binding cassette sub-family G member 2transporter
DB00709LamivudineReverse transcriptase/RNaseHtarget
DB00709LamivudineSolute carrier family 22 member 1transporter
DB00709LamivudineSolute carrier family 22 member 2transporter
DB00709LamivudineSolute carrier family 22 member 3transporter
DB00709LamivudineDeoxycytidine kinaseenzyme
DB00709LamivudineUMP-CMP kinaseenzyme
DB00709LamivudinePhosphoglycerate kinase 1enzyme
DB00709LamivudineNucleoside diphosphate kinase Aenzyme
DB00709LamivudineNucleoside diphosphate kinase Benzyme
DB00709LamivudineCholine-phosphate cytidylyltransferase Aenzyme
DB00709LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
DB00709LamivudineP-glycoprotein 1transporter
DB00709LamivudineMultidrug resistance-associated protein 4transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 2transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 1transporter
DB00709Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
DB00709LamivudineSerum albumincarrier
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB01265TelbivudineProtein Ptarget
DB01265TelbivudineDNAtarget
DB09299Tenofovir alafenamideReverse transcriptase/RNaseHtarget
DB09299Tenofovir alafenamideP-glycoprotein 1transporter
DB09299Tenofovir alafenamideMultidrug resistance-associated protein 4transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 6transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 8transporter
DB09299Tenofovir alafenamideLysosomal protective proteinenzyme
DB09299Tenofovir alafenamideLiver carboxylesterase 1enzyme
DB09299Tenofovir alafenamideATP-binding cassette sub-family G member 2transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
DB09299Tenofovir alafenamideReverse transcriptasetarget
DB09299Tenofovir alafenamideDNA polymerasetarget
DB09299Tenofovir alafenamideSerum albumincarrier
DB09299Tenofovir alafenamideCytochrome P450 3A4enzyme
DB09299Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
DB09299Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
DB00300Tenofovir disoproxilReverse transcriptase/RNaseHtarget
DB00300Tenofovir disoproxilSolute carrier family 22 member 6transporter
DB00300Tenofovir disoproxilSolute carrier family 22 member 8transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 7transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 4transporter
DB00300Tenofovir disoproxilCanalicular multispecific organic anion transporter 1transporter
DB00300Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
DB00300Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
DB00300Tenofovir disoproxilP-glycoprotein 1transporter
DB00300Tenofovir disoproxilNucleoside diphosphokinaseenzyme
DB00300Tenofovir disoproxilCreatine Kinasesenzyme
DB00300Tenofovir disoproxilDNA polymerase/reverse transcriptasetarget
DrugDrug NamePhaseStatusCount
DB05020ANA3801Completed1
DB13868Adefovir1Completed1
DB00718Adefovir dipivoxil1Completed1
DB00442Entecavir1Completed5
DB00442Entecavir1Terminated1
DB00736Esomeprazole1Not Yet Recruiting1
DB00977Ethinylestradiol1Not Yet Recruiting1
DB11627Hepatitis B Vaccine (Recombinant)1Unknown Status1
DB01167Itraconazole1Not Yet Recruiting1
DB00709Lamivudine1Completed1
DB00367Levonorgestrel1Not Yet Recruiting1
DB00683Midazolam1Not Yet Recruiting1
DB00683Midazolam1Recruiting1
DB00008Peginterferon alfa-2a1Completed6
DB01045Rifampicin1Not Yet Recruiting1
DB00503Ritonavir1Completed1
DB01265Telbivudine1Completed1
DB14126Tenofovir1Completed1
DB09299Tenofovir alafenamide1Completed1
DB00300Tenofovir disoproxil1Completed4
DB00300Tenofovir disoproxil1Terminated1
DB05020ANA3801 / 2Completed1
DB05396Albinterferon Alfa-2B1 / 2Terminated1
DB00062Albumin human1 / 2Completed1
DB00442Entecavir1 / 2Completed3
DB00442Entecavir1 / 2Not Yet Recruiting1
DB00442Entecavir1 / 2Unknown Status2
DB11627Hepatitis B Vaccine (Recombinant)1 / 2Not Yet Recruiting2
DB11627Hepatitis B Vaccine (Recombinant)1 / 2Recruiting1
DB11997Interleukin-71 / 2Unknown Status1
DB12232KRN-70001 / 2Completed1
DB14853Myrcludex B1 / 2Completed1
DB00008Peginterferon alfa-2a1 / 2Completed3
DB00008Peginterferon alfa-2a1 / 2Not Yet Recruiting1
DB00008Peginterferon alfa-2a1 / 2Terminated1
DB00008Peginterferon alfa-2a1 / 2Unknown Status1
DB05386Regramostim1 / 2Unknown Status1
DB01265Telbivudine1 / 2Completed1
DB01265Telbivudine1 / 2Not Yet Recruiting1
DB14126Tenofovir1 / 2Completed1
DB14126Tenofovir1 / 2Unknown Status1
DB00300Tenofovir disoproxil1 / 2Completed1
DB04900Thymalfasin1 / 2Completed1
DB05020ANA3802Completed1
DB05020ANA3802Unknown Status1
DB13868Adefovir2Completed2
DB13868Adefovir2Terminated1
DB00718Adefovir dipivoxil2Recruiting1
DB12326Antroquinonol2Recruiting1
DB01114Chlorpheniramine2Terminated1
DB01075Diphenhydramine2Terminated1
DB06236Elvucitabine2Terminated1
DB00879Emtricitabine2Completed5
DB00442Entecavir2Active Not Recruiting1
DB00442Entecavir2Completed10
DB00442Entecavir2Not Yet Recruiting2
DB00442Entecavir2Recruiting3
DB00442Entecavir2Terminated2
DB00442Entecavir2Unknown Status1
DB05276Hepatitis B Immune Globulin2Completed2
DB05276Hepatitis B Immune Globulin2Recruiting1
DB06299Hydronidone2Recruiting1
DB15062Inarigivir2Active Not Recruiting1
DB15063Inarigivir soproxil2Active Not Recruiting1
DB15063Inarigivir soproxil2Recruiting3
DB05258Interferon alfa2Recruiting1
DB00709Lamivudine2Completed3
DB00507Nitazoxanide2Recruiting1
DB00008Peginterferon alfa-2a2Completed7
DB00008Peginterferon alfa-2a2Withdrawn1
DB00022Peginterferon alfa-2b2Completed1
DB15550Pradefovir2Completed1
DB15550Pradefovir2Terminated1
DB05478Pradefovir Mesylate2Terminated1
DB05386Regramostim2Completed1
DB00503Ritonavir2Recruiting1
DB01265Telbivudine2Completed1
DB14126Tenofovir2Active Not Recruiting1
DB14126Tenofovir2Completed2
DB14126Tenofovir2Recruiting1
DB09299Tenofovir alafenamide2Active Not Recruiting4
DB09299Tenofovir alafenamide2Recruiting2
DB00300Tenofovir disoproxil2Completed9
DB00300Tenofovir disoproxil2Not Yet Recruiting1
DB00300Tenofovir disoproxil2Recruiting2
DB00300Tenofovir disoproxil2Terminated1
DB12687Vesatolimod2Completed2
DB11627Hepatitis B Vaccine (Recombinant)2 / 3Completed1
DB00811Ribavirin2 / 3Completed1
DB13868Adefovir3Completed2
DB13868Adefovir3Terminated1
DB13868Adefovir3Unknown Status1
DB00718Adefovir dipivoxil3Approved for Marketing1
DB00718Adefovir dipivoxil3Completed10
DB00718Adefovir dipivoxil3Recruiting1
DB06683Clevudine3Completed1
DB00879Emtricitabine3Completed2
DB00879Emtricitabine3Terminated1
DB00442Entecavir3Active Not Recruiting1
DB00442Entecavir3Completed8
DB00442Entecavir3Recruiting1
DB00442Entecavir3Terminated2
DB00442Entecavir3Unknown Status1
DB05276Hepatitis B Immune Globulin3Withdrawn1
DB09053Ibrutinib3Recruiting1
DB05258Interferon alfa3Completed1
DB05258Interferon alfa3Unknown Status1
DB00105Interferon alfa-2b3Completed1
DB00105Interferon alfa-2b3Terminated1
DB00709Lamivudine3Active Not Recruiting1
DB00709Lamivudine3Completed9
DB00709Lamivudine3Terminated1
DB00008Peginterferon alfa-2a3Active Not Recruiting2
DB00008Peginterferon alfa-2a3Completed5
DB00008Peginterferon alfa-2a3Terminated2
DB00008Peginterferon alfa-2a3Unknown Status4
DB00022Peginterferon alfa-2b3Completed1
DB00022Peginterferon alfa-2b3Recruiting1
DB00022Peginterferon alfa-2b3Terminated1
DB00022Peginterferon alfa-2b3Unknown Status1
DB00811Ribavirin3Recruiting1
DB00811Ribavirin3Unknown Status1
DB01265Telbivudine3Completed8
DB01265Telbivudine3Terminated1
DB01265Telbivudine3Unknown Status1
DB14126Tenofovir3Active Not Recruiting1
DB14126Tenofovir3Completed1
DB14126Tenofovir3Recruiting2
DB14126Tenofovir3Terminated1
DB09299Tenofovir alafenamide3Active Not Recruiting1
DB00300Tenofovir disoproxil3Active Not Recruiting2
DB00300Tenofovir disoproxil3Completed5
DB00300Tenofovir disoproxil3Enrolling by Invitation1
DB00300Tenofovir disoproxil3Recruiting1
DB00300Tenofovir disoproxil3Terminated2
DB13868Adefovir4Active Not Recruiting1
DB13868Adefovir4Completed5
DB13868Adefovir4Recruiting2
DB13868Adefovir4Terminated1
DB13868Adefovir4Unknown Status3
DB13868Adefovir4Withdrawn1
DB00718Adefovir dipivoxil4Active Not Recruiting2
DB00718Adefovir dipivoxil4Completed13
DB00718Adefovir dipivoxil4Not Yet Recruiting1
DB00718Adefovir dipivoxil4Recruiting1
DB00718Adefovir dipivoxil4Terminated1
DB00718Adefovir dipivoxil4Unknown Status4
DB00718Adefovir dipivoxil4Withdrawn2
DB06683Clevudine4Completed3
DB06683Clevudine4Terminated4
DB00879Emtricitabine4Not Yet Recruiting3
DB00879Emtricitabine4Unknown Status2
DB00442Entecavir4Active Not Recruiting4
DB00442Entecavir4Completed18
DB00442Entecavir4Not Yet Recruiting2
DB00442Entecavir4Recruiting11
DB00442Entecavir4Terminated3
DB00442Entecavir4Unknown Status11
DB00442Entecavir4Withdrawn2
DB10993Hepatitis B Vaccine (Recombinant)4Completed1
DB11627Hepatitis B Vaccine (Recombinant)4Completed2
DB11627Hepatitis B Vaccine (Recombinant)4Unknown Status1
DB05258Interferon alfa4Recruiting1
DB00034Interferon alfa-2a, Recombinant4Completed1
DB00105Interferon alfa-2b4Completed1
DB00709Lamivudine4Active Not Recruiting1
DB00709Lamivudine4Completed13
DB00709Lamivudine4Recruiting2
DB00709Lamivudine4Terminated2
DB00709Lamivudine4Unknown Status6
DB00709Lamivudine4Withdrawn2
DB00008Peginterferon alfa-2a4Active Not Recruiting2
DB00008Peginterferon alfa-2a4Completed18
DB00008Peginterferon alfa-2a4Recruiting11
DB00008Peginterferon alfa-2a4Terminated1
DB00008Peginterferon alfa-2a4Unknown Status4
DB00008Peginterferon alfa-2a4Withdrawn1
DB00022Peginterferon alfa-2b4Active Not Recruiting1
DB00022Peginterferon alfa-2b4Completed1
DB00022Peginterferon alfa-2b4Recruiting3
DB00860Prednisolone4Unknown Status1
DB00811Ribavirin4Unknown Status1
DB01265Telbivudine4Active Not Recruiting2
DB01265Telbivudine4Completed12
DB01265Telbivudine4Unknown Status6
DB01265Telbivudine4Withdrawn3
DB14126Tenofovir4Active Not Recruiting1
DB14126Tenofovir4Completed2
DB14126Tenofovir4Unknown Status1
DB14126Tenofovir4Withdrawn1
DB09299Tenofovir alafenamide4Active Not Recruiting2
DB09299Tenofovir alafenamide4Recruiting3
DB00300Tenofovir disoproxil4Active Not Recruiting6
DB13426Tenofovir disoproxil4Active Not Recruiting1
DB00300Tenofovir disoproxil4Completed10
DB00300Tenofovir disoproxil4Enrolling by Invitation1
DB00300Tenofovir disoproxil4Recruiting5
DB00300Tenofovir disoproxil4Unknown Status3
DB00163Vitamin E4Unknown Status1
DB01281AbataceptNot AvailableRecruiting1
DB00718Adefovir dipivoxilNot AvailableActive Not Recruiting1
DB00718Adefovir dipivoxilNot AvailableCompleted1
DB00126Ascorbic acidNot AvailableTemporarily Not Available1
DB00442EntecavirNot AvailableCompleted5
DB00442EntecavirNot AvailableNot Yet Recruiting2
DB00442EntecavirNot AvailableRecruiting3
DB00442EntecavirNot AvailableUnknown Status2
DB05276Hepatitis B Immune GlobulinNot AvailableCompleted1
DB05276Hepatitis B Immune GlobulinNot AvailableRecruiting1
DB11627Hepatitis B Vaccine (Recombinant)Not AvailableCompleted1
DB05258Interferon alfaNot AvailableActive Not Recruiting1
DB05258Interferon alfaNot AvailableCompleted1
DB05258Interferon alfaNot AvailableNot Yet Recruiting1
DB00709LamivudineNot AvailableCompleted2
DB00331MetforminNot AvailableNot Yet Recruiting1
DB00008Peginterferon alfa-2aNot AvailableCompleted7
DB00008Peginterferon alfa-2aNot AvailableNot Yet Recruiting2
DB00008Peginterferon alfa-2aNot AvailableRecruiting2
DB00022Peginterferon alfa-2bNot AvailableRecruiting1
DB00022Peginterferon alfa-2bNot AvailableUnknown Status1
DB00635PrednisoneNot AvailableWithdrawn1
DB05386RegramostimNot AvailableRecruiting1
DB01265TelbivudineNot AvailableCompleted1
DB01265TelbivudineNot AvailableWithdrawn2
DB14126TenofovirNot AvailableRecruiting1
DB14126TenofovirNot AvailableTemporarily Not Available1
DB14126TenofovirNot AvailableWithdrawn1
DB09299Tenofovir alafenamideNot AvailableRecruiting2
DB00300Tenofovir disoproxilNot AvailableActive Not Recruiting2
DB00300Tenofovir disoproxilNot AvailableCompleted2
DB00300Tenofovir disoproxilNot AvailableRecruiting4
DB00300Tenofovir disoproxilNot AvailableTerminated1
DB12687VesatolimodNot AvailableTerminated1