Macular Edema (ME)

Also known as: Edema Macular / Macular Oedema / Macular Edema

DrugDrug NameDrug Description
DB08885AfliberceptA vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB01270RanibizumabA recombinant humanized monoclonal antibody and VEGF-A antagonist used for the management of macular edema after retinal vein occlusion, age-related macular degeneration (wet), and diabetic macular edema.
DrugDrug NameTargetType
DB08885AfliberceptVascular endothelial growth factor Atarget
DB08885AfliberceptPlacenta growth factortarget
DB08885AfliberceptVascular endothelial growth factor Btarget
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01270RanibizumabVascular endothelial growth factor Atarget
DrugDrug NamePhaseStatusCount
DB08885Aflibercept1Active Not Recruiting1
DB08885Aflibercept1Recruiting1
DB01234Dexamethasone1Recruiting1
DB05311Ecallantide1Terminated1
DB00095Efalizumab1Completed1
DB00163Vitamin E1Completed2
DB01234Dexamethasone1 / 2Completed2
DB01234Dexamethasone1 / 2Terminated1
DB01270Ranibizumab1 / 2Completed3
DB06461Squalamine1 / 2Completed1
DB12258Abicipar Pegol2Completed1
DB00819Acetazolamide2Completed1
DB08885Aflibercept2Completed1
DB00112Bevacizumab2Completed3
DB00112Bevacizumab2Terminated1
DB00112Bevacizumab2Unknown Status1
DB00484Brimonidine2Completed1
DB01234Dexamethasone2Completed3
DB01234Dexamethasone2Recruiting1
DB01234Dexamethasone2Terminated1
DB00898Ethanol2Completed1
DB00591Fluocinolone acetonide2Terminated1
DB00465Ketorolac2Completed2
DB06802Nepafenac2Completed2
DB06802Nepafenac2Unknown Status1
DB11077Polyethylene glycol 4002Completed1
DB15566Prednisolone acetate2Completed1
DB11078Propylene glycol2Completed1
DB01270Ranibizumab2Completed5
DB01270Ranibizumab2Terminated1
DB01270Ranibizumab2Unknown Status2
DB01270Ranibizumab2Withdrawn1
DB00620Triamcinolone2Terminated1
DB00620Triamcinolone2Withdrawn1
DB00460Verteporfin2Completed1
DB00112Bevacizumab2 / 3Completed1
DB00112Bevacizumab2 / 3Unknown Status1
DB01234Dexamethasone2 / 3Completed1
DB00620Triamcinolone2 / 3Completed1
DB08885Aflibercept3Completed4
DB08885Aflibercept3Terminated1
DB00112Bevacizumab3Completed2
DB12460Conbercept3Recruiting2
DB01234Dexamethasone3Active Not Recruiting1
DB01234Dexamethasone3Completed5
DB01234Dexamethasone3Recruiting1
DB01234Dexamethasone3Unknown Status1
DB00563Methotrexate3Completed1
DB00563Methotrexate3Recruiting1
DB04895Pegaptanib3Completed1
DB01270Ranibizumab3Completed12
DB01270Ranibizumab3Recruiting1
DB00620Triamcinolone3Completed3
DB00620Triamcinolone3Unknown Status1
DB08885Aflibercept4Completed2
DB08885Aflibercept4Recruiting2
DB00112Bevacizumab4Completed1
DB00112Bevacizumab4Recruiting1
DB00112Bevacizumab4Unknown Status2
DB01234Dexamethasone4Completed3
DB01234Dexamethasone4Recruiting3
DB06781Difluprednate4Recruiting1
DB00328Indomethacin4Completed1
DB00465Ketorolac4Completed1
DB00563Methotrexate4Terminated1
DB06802Nepafenac4Completed1
DB06802Nepafenac4Recruiting1
DB11133Omega-3 fatty acids4Completed1
DB13514Pranoprofen4Completed1
DB15566Prednisolone acetate4Recruiting1
DB01270Ranibizumab4Completed4
DB01270Ranibizumab4Recruiting2
DB01270Ranibizumab4Terminated1
DB00620Triamcinolone4Unknown Status1
DB08885AfliberceptNot AvailableActive Not Recruiting1
DB08885AfliberceptNot AvailableCompleted1
DB08885AfliberceptNot AvailableRecruiting2
DB00112BevacizumabNot AvailableCompleted4
DB01234DexamethasoneNot AvailableCompleted11
DB01234DexamethasoneNot AvailableRecruiting2
DB01234DexamethasoneNot AvailableTerminated3
DB00586DiclofenacNot AvailableCompleted2
DB00465KetorolacNot AvailableCompleted1
DB01270RanibizumabNot AvailableCompleted5
DB01270RanibizumabNot AvailableRecruiting1
DB01270RanibizumabNot AvailableUnknown Status2
DB01270RanibizumabNot AvailableWithdrawn1
DB00620TriamcinoloneNot AvailableCompleted1