Gram Positive Bacterial Infections

Also known as: Gram Positive Bacterial Infection / Infections, Gram-Positive Bacterial / Gram-positive Bacterial Infection / Gram-Positive Bacterial Infections / Bacterial infection, unspecified / Bacterial infectious disease (disorder) / Bacterial infection / Bacterial Infections / Bacterial infection of unspecified site / Bacterial infectious disorders / Bacterial infection NOS / Infection bacterial

Drug	Drug Name	Drug Description
DB13682	Cefpirome	An antibiotic indicated in the treatment of a wide variety of infections in the body.
DB06219	Dalbavancin	An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria.
DB04911	Oritavancin	An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria.

Drug	Drug Name	Target	Type
DB06219	Dalbavancin	D-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycan	target
DB04911	Oritavancin	Cytochrome P450 3A4	enzyme
DB04911	Oritavancin	Cytochrome P450 2D6	enzyme
DB04911	Oritavancin	Cytochrome P450 2C9	enzyme
DB04911	Oritavancin	Cytochrome P450 2C19	enzyme
DB04911	Oritavancin	Serum albumin	carrier
DB04911	Oritavancin	Peptidoglycan precursors	target
DB04911	Oritavancin	Bacterial cell wall peptide bridging segments	target
DB04911	Oritavancin	Pentaglycyl bridging segment	target

Drug	Drug Name	Phase	Status	Count
DB00080	Daptomycin	1	Completed	2
DB04911	Oritavancin	1	Recruiting	1
DB09042	Tedizolid phosphate	1	Completed	1
DB01053	Benzylpenicillin	2	Completed	2
DB01147	Cloxacillin	2	Completed	1
DB00080	Daptomycin	2	Unknown Status	1
DB00601	Linezolid	2	Completed	1
DB00607	Nafcillin	2	Completed	1
DB00713	Oxacillin	2	Completed	1
DB16312	TNP-2092	2	Completed	1
DB06402	Telavancin	2	Completed	3
DB00512	Vancomycin	2	Completed	4
DB06219	Dalbavancin	2 / 3	Terminated	1
DB08903	Bedaquiline	3	Active Not Recruiting	1
DB01327	Cefazolin	3	Terminated	1
DB14733	Ceftobiprole medocaril	3	Terminated	1
DB00845	Clofazimine	3	Active Not Recruiting	1
DB01764	Dalfopristin	3	Terminated	1
DB00080	Daptomycin	3	Terminated	1
DB11637	Delamanid	3	Active Not Recruiting	1
DB00485	Dicloxacillin	3	Completed	1
DB00601	Linezolid	3	Active Not Recruiting	1
DB00601	Linezolid	3	Completed	1
DB00601	Linezolid	3	Terminated	1
DB00713	Oxacillin	3	Completed	1
DB01369	Quinupristin	3	Terminated	1
DB00560	Tigecycline	3	Completed	2
DB00512	Vancomycin	3	Completed	1
DB00512	Vancomycin	3	Terminated	1
DB06219	Dalbavancin	4	Withdrawn	1
DB00601	Linezolid	4	Completed	1
DB06402	Telavancin	4	Terminated	1
DB00512	Vancomycin	4	Unknown Status	1
DB00601	Linezolid	Not Available	Completed	2
DB04911	Oritavancin	Not Available	Completed	1
DB00319	Piperacillin	Not Available	Completed	2
DB01606	Tazobactam	Not Available	Completed	2