Pheochromocytomas

Also known as: Pheochromocytoma / Chromaffinoma / Phaeochromocytoma

DrugDrug NameDrug Description
DB01193AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
DB00531CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
DB00851DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
DB00598LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
DB00765MetyrosineA tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma.
DB00925PhenoxybenzamineAn alpha adrenergic agonist used to treat pheochromocytoma and episodes of hypertension and sweating.
DB00692PhentolamineAn alpha adrenergic antagonist used to reverse soft tissue anesthesia.
DB00571PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
DB00541VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DrugDrug NameTargetType
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololP-glycoprotein 1transporter
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB00851DacarbazineDNA polymerase alpha subunit Btarget
DB00851DacarbazineCytochrome P450 1A1enzyme
DB00851DacarbazineCytochrome P450 1A2enzyme
DB00851DacarbazineCytochrome P450 2E1enzyme
DB00851Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00851DacarbazineDNAtarget
DB00598LabetalolAlpha-1 adrenergic receptorstarget
DB00598LabetalolBeta-1 adrenergic receptortarget
DB00598LabetalolBeta-2 adrenergic receptortarget
DB00598LabetalolCytochrome P450 2D6enzyme
DB00598LabetalolCytochrome P450 2C19enzyme
DB00598LabetalolSerum albumincarrier
DB00598Labetalolalpha1-acid glycoproteincarrier
DB00598LabetalolATP-binding cassette sub-family B member 5transporter
DB00598LabetalolUDP-glucuronosyltransferase 1-1enzyme
DB00598LabetalolUDP-glucuronosyltransferase 2B7enzyme
DB00598LabetalolUDP-glucuronosyltransferase 1-9enzyme
DB00765MetyrosineTyrosine 3-monooxygenasetarget
DB00925PhenoxybenzamineAlpha-1A adrenergic receptortarget
DB00925PhenoxybenzamineCalmodulintarget
DB00925PhenoxybenzamineSolute carrier family 22 member 2transporter
DB00925PhenoxybenzamineSolute carrier family 22 member 1transporter
DB00925PhenoxybenzamineSolute carrier family 22 member 3transporter
DB00925PhenoxybenzamineAlpha-2A adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-2C adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-2B adrenergic receptortarget
DB00925PhenoxybenzamineBeta-2 adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-1B adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-1D adrenergic receptortarget
DB00692PhentolamineAlpha-2A adrenergic receptortarget
DB00692PhentolamineAlpha-1A adrenergic receptortarget
DB00692PhentolamineAlpha-1B adrenergic receptortarget
DB00692PhentolamineAlpha-1D adrenergic receptortarget
DB00571PropranololBeta-1 adrenergic receptortarget
DB00571PropranololBeta-2 adrenergic receptortarget
DB00571PropranololBeta-3 adrenergic receptortarget
DB00571Propranolol5-hydroxytryptamine receptor 1Atarget
DB00571Propranolol5-hydroxytryptamine receptor 1Btarget
DB00571PropranololCytochrome P450 1A2enzyme
DB00571PropranololCytochrome P450 2D6enzyme
DB00571PropranololAlpha-1-acid glycoprotein 1carrier
DB00571PropranololCytochrome P450 2C19enzyme
DB00571PropranololCytochrome P450 3A4enzyme
DB00571PropranololCytochrome P450 3A5enzyme
DB00571PropranololCytochrome P450 3A7enzyme
DB00571PropranololSolute carrier family 22 member 2transporter
DB00571PropranololP-glycoprotein 1transporter
DB00571PropranololCytochrome P450 1A1enzyme
DB00571PropranololAmine oxidase [flavin-containing] Aenzyme
DB00571PropranololSerum albumincarrier
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineP-glycoprotein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB06704Iobenguane1Completed1
DB00683Midazolam1Active Not Recruiting1
DB00220Nelfinavir1Active Not Recruiting1
DB06704Iobenguane1 / 2Completed1
DB13985Lutetium Lu 177 dotatate1 / 2Not Yet Recruiting1
DB06626Axitinib2Active Not Recruiting1
DB06626Axitinib2Recruiting1
DB00515Cisplatin2Completed1
DB14554Dotatate2Recruiting1
DB00997Doxorubicin2Completed1
DB01590Everolimus2Completed1
DB12010Fostamatinib2Completed1
DB11918Guadecitabine2Recruiting1
DB06791Lanreotide2Not Yet Recruiting1
DB13982Lutetium Lu-1772Recruiting1
DB00104Octreotide2Terminated1
DB01268Sunitinib2Active Not Recruiting1
DB00675Tamoxifen2Completed1
DB00590Doxazosin3Recruiting1
DB00997Doxorubicin3Completed2
DB00099Filgrastim3Completed2
DB01181Ifosfamide3Completed2
DB06704Iobenguane3Completed1
DB00925Phenoxybenzamine3Recruiting1
DB00590Doxazosin4Completed1
DB00925Phenoxybenzamine4Completed1
DB06704IobenguaneNot AvailableApproved for Marketing1
DB06704IobenguaneNot AvailableAvailable2