Stage 4 Chronic Kidney Disease

Also known as: CKD Stage 4 / Chronic Kidney Disease Stage 4 / Chronic kidney disease / Chronic Kidney Diseases / Chronic kidney disease (CKD)

Drug	Drug Name	Drug Description
DB00146	Calcifediol	An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients.
DB06410	Doxercalciferol	A synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis.
DB00910	Paricalcitol	A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease.

Drug	Drug Name	Target	Type
DB00146	Calcifediol	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	enzyme
DB00146	Calcifediol	Vitamin D3 receptor	target
DB00146	Calcifediol	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	enzyme
DB06410	Doxercalciferol	Sterol 26-hydroxylase, mitochondrial	enzyme
DB06410	Doxercalciferol	Vitamin D3 receptor	target
DB00910	Paricalcitol	Vitamin D3 receptor	target
DB00910	Paricalcitol	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	enzyme
DB00910	Paricalcitol	Cytochrome P450 3A4	enzyme
DB00910	Paricalcitol	UDP-glucuronosyltransferase 1-4	enzyme

Drug	Drug Name	Phase	Status	Count
DB00945	Acetylsalicylic acid	3	Unknown Status	1
DB00012	Darbepoetin alfa	3	Recruiting	1
DB00658	Sevelamer	3	Not Yet Recruiting	1
DB00146	Calcifediol	4	Recruiting	1
DB00169	Cholecalciferol	4	Recruiting	1
DB00910	Paricalcitol	4	Recruiting	1