Stage 4 Chronic Kidney Disease

Also known as: CKD Stage 4 / Chronic Kidney Disease Stage 4 / Chronic kidney disease / Chronic Kidney Diseases / Chronic kidney disease (CKD)

DrugDrug NameDrug Description
DB00146CalcifediolThe major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
DB06410DoxercalciferolDoxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. Doxercalciferol is marketed under the brand name Hectoral by Genzyme Corporation, and is manufactured by Catalent Pharma Solutions, Inc.
DB00910ParicalcitolParicalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
DrugDrug NamePhaseStatusCount
DB00945Acetylsalicylic acid3Unknown Status1
DB00658Sevelamer3Not Yet Recruiting1
DB00146Calcifediol4Recruiting1
DB00169Cholecalciferol4Recruiting1
DB00910Paricalcitol4Recruiting1