Acute Myeloid Leukaemias (AML)

Also known as: Leukemia, Myeloid, Acute(AML) / Acute Myeloid Leukaemia / Leukemia Myeloid Acute / Acute Myeloid Leukemia / Leukemia, Acute Myeloid / Myeloid Leukemia, Acute / Acute Myeloid Leukemia (AML) / Acute Myeloid Leukaemia (AML) / Leukemia Acute Myeloid / Leukaemias acute myeloid / Acute Myeloid Leukemia NOS / Leukemia, Myeloid, Acute / Leukemia, Myeloid Acute / Acute Myeloid Leucemia / Leukemia Acute Myeloid - AML / Acute Myeloid Leukemias / AML / Acute Granulocytic Leukemia / Acute Myeloid Leucaemia / Leukemia Acute Myeloid Leukemia (AML) / Leukemia, Acute Myeloid (AML) / Acute myelocytic leukaemia / Acute myelocytic leukemia / Acute myeloblastic leukemia with failed remission / Leukaemia myeloblastic acute / Non-lymphoblastic leukaemia acute / Non-lymphoblastic leukemia acute / Myeloid leukaemia, acute / Acute myeloblastic leukemia / Acute myeloblastic leukaemia / Leukemia myeloblastic acute / Acute granulocytic leukaemia / Acute myeloid leukaemia NOS

DrugDrug NameDrug Description
DB00928AzacitidineA pyrimidine nucleoside analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent. [PubChem]
DB00987CytarabineA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
DB00694DaunorubicinA very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms. [PubChem]
DB01262DecitabineDecitabine is indicated for treatment of patients with myelodysplastic syndrome (MDS). It is a chemical analogue of cytidine, a nucleoside present in DNA and RNA. Cells in the presence of Decitabine incorporate it into DNA during replication and RNA during transcription. The incorporation of Decitabine into DNA or RNA inhibits methyltransferase thereby causing demethylation in that sequence. This adversely affects the way that cell regulatory proteins are able to bind to the DNA/RNA substrate.
DB00773EtoposideA semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. [PubChem]
DB00056Gemtuzumab ozogamicinGemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody [FDA Label]. The antibody is specifically directed against the CD33 antigen present on leukemic myeloblasts in most patients with acute myeloid leukemia (AML). By binding to the CD33 antigen on tumors, the cytotoxic agent blocks the growth of cancerous cells and causes cell death. Marketing approval of gemtuzumab ozogamicin was granted on May 17, 2000 by FDA as a treatment for patients with CD33-positive AML in first relapse who are 60 years of age or older and who are not considered candidates for cytotoxic chemotherapy [A98]. However, it was voluntarily withdrawn from the market in 2010 due to safety concerns, increased patient deaths and insufficient evidence of clinical benefit during confirmatory trials [L941]. On September 1 2017, gemtuzumab ozogamicin was again approved for the treatment of adults with newly diagnosed CD33-positive acute myeloid leukemia but with a lower dosing regimen and a different schedule in combination with chemotherapy or on its own [L941]. It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who have experienced a relapse or who have not responded to initial treatment (refractory) [L941].
DB01177IdarubicinAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity. [PubChem]
DB06595MidostaurinMidostaurin (as Rydapt) is a multitarget kinase inhibitor for the treatment for adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3. It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors [A19108]. It was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents.
DB01204MitoxantroneAn anthracenedione-derived antineoplastic agent. [PubChem]
DB01030TopotecanAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I. [PubChem]
DrugDrug NameTargetType
DB00928AzacitidineDNA (cytosine-5)-methyltransferase 1target
DB00928AzacitidineCytidine deaminaseenzyme
DB00928AzacitidineDNAtarget
DB00928AzacitidineRNAtarget
DB00987CytarabineDNA polymerase betatarget
DB00987CytarabineCytidine deaminaseenzyme
DB00987CytarabineSolute carrier family 22 member 2transporter
DB00987CytarabineSolute carrier family 22 member 1transporter
DB00987CytarabineMultidrug resistance-associated protein 7transporter
DB00987CytarabineEquilibrative nucleoside transporter 1transporter
DB00987CytarabineDNAtarget
DB00987CytarabineCytochrome P450 3A4enzyme
DB00987CytarabineDeoxycytidine kinaseenzyme
DB00987Cytarabine5'-nucleotidaseenzyme
DB00987CytarabineDeoxycytidylate deaminaseenzyme
DB00694DaunorubicinDNAtarget
DB00694DaunorubicinXanthine dehydrogenase/oxidaseenzyme
DB00694DaunorubicinCytochrome P450 3A5enzyme
DB00694DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DB00694DaunorubicinMultidrug resistance protein 1transporter
DB00694DaunorubicinMultidrug resistance-associated protein 1transporter
DB00694DaunorubicinCanalicular multispecific organic anion transporter 1transporter
DB00694DaunorubicinSolute carrier family 22 member 2transporter
DB00694DaunorubicinMultidrug resistance-associated protein 6transporter
DB00694DaunorubicinBile salt export pumptransporter
DB00694DaunorubicinMultidrug resistance-associated protein 7transporter
DB00694DaunorubicinATP-binding cassette sub-family G member 2transporter
DB00694DaunorubicinDNA topoisomerase 2-alphatarget
DB00694DaunorubicinDNA topoisomerase 2-betatarget
DB00694DaunorubicinCytochrome P450 1A1enzyme
DB00694DaunorubicinCytochrome P450 1A2enzyme
DB00694DaunorubicinCytochrome P450 1B1enzyme
DB00694DaunorubicinCytochrome P450 3A4enzyme
DB01262DecitabineDNAtarget
DB01262DecitabineDNA (cytosine-5)-methyltransferase 1target
DB01262DecitabineDeoxycytidine kinaseenzyme
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideMultidrug resistance protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2C8enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB00056Gemtuzumab ozogamicinMyeloid cell surface antigen CD33target
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00056Gemtuzumab ozogamicinComplement C1r subcomponenttarget
DB00056Gemtuzumab ozogamicinComplement C1q subcomponent subunit Atarget
DB00056Gemtuzumab ozogamicinComplement C1q subcomponent subunit Btarget
DB00056Gemtuzumab ozogamicinComplement C1q subcomponent subunit Ctarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00056Gemtuzumab ozogamicinComplement C1s subcomponenttarget
DB00056Gemtuzumab ozogamicinHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB01177IdarubicinDNA topoisomerase 2-alphatarget
DB01177IdarubicinDNAtarget
DB01177IdarubicinMultidrug resistance-associated protein 1transporter
DB01177IdarubicinCytochrome P450 2C9enzyme
DB01177IdarubicinCytochrome P450 2D6enzyme
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCytochrome p450 3A subfamilyenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB01204MitoxantroneDNA topoisomerase 2-alphatarget
DB01204MitoxantroneCytochrome P450 2E1enzyme
DB01204MitoxantroneMultidrug resistance protein 1transporter
DB01204MitoxantroneMultidrug resistance-associated protein 1transporter
DB01204MitoxantroneATP-binding cassette sub-family G member 2transporter
DB01204MitoxantroneDNAtarget
DB01204MitoxantroneCytochrome P450 1B1enzyme
DB01204MitoxantroneCytochrome P450 3A4enzyme
DB01030TopotecanDNA topoisomerase I, mitochondrialtarget
DB01030TopotecanDNA topoisomerase 1target
DB01030TopotecanATP-binding cassette sub-family G member 2transporter
DB01030TopotecanMultidrug resistance protein 1transporter
DB01030TopotecanCytochrome P450 3A4enzyme
DB01030TopotecanDNAtarget
DrugDrug NamePhaseStatusCount
DB09134Ioversol0Completed1
DB09037Pembrolizumab0Recruiting1
DB126694SC-2031Completed1
DB04974AP19031Active Not Recruiting1
DB04974AP19031Recruiting1
DB03496Alvocidib1Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)1Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)1Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)1Terminated1
DB00023Asparaginase1Active Not Recruiting1
DB11595Atezolizumab1Recruiting1
DB00928Azacitidine1Active Not Recruiting3
DB00928Azacitidine1Completed5
DB00928Azacitidine1Recruiting6
DB00928Azacitidine1Terminated2
DB11747Barasertib1Completed3
DB05015Belinostat1Active Not Recruiting1
DB05015Belinostat1Completed1
DB00307Bexarotene1Completed2
DB11967Binimetinib1Completed1
DB00188Bortezomib1Active Not Recruiting1
DB00188Bortezomib1Completed2
DB00188Bortezomib1Recruiting1
DB08870Brentuximab vedotin1Active Not Recruiting1
DB01008Busulfan1Active Not Recruiting1
DB01008Busulfan1Completed4
DB01008Busulfan1Recruiting2
DB01008Busulfan1Terminated1
DB11059Carboxymethylcellulose1Completed1
DB11059Carboxymethylcellulose1Not Yet Recruiting1
DB08889Carfilzomib1Completed1
DB00493Cefotaxime1Active Not Recruiting1
DB00493Cefotaxime1Completed1
DB00493Cefotaxime1Recruiting1
DB01188Ciclopirox1Completed1
DB00242Cladribine1Completed1
DB04815Clioquinol1Terminated1
DB00631Clofarabine1Active Not Recruiting1
DB00631Clofarabine1Completed5
DB06189Clofarabine1Completed3
DB00631Clofarabine1Terminated1
DB06189Clofarabine1Terminated1
DB00631Clofarabine1Unknown Status1
DB00631Clofarabine1Withdrawn1
DB06189Clofarabine1Withdrawn1
DB09110Coenzyme M1Completed1
DB11832Crenolanib1Completed1
DB00531Cyclophosphamide1Active Not Recruiting1
DB00531Cyclophosphamide1Completed2
DB00531Cyclophosphamide1Not Yet Recruiting1
DB00531Cyclophosphamide1Recruiting3
DB00531Cyclophosphamide1Terminated1
DB00531Cyclophosphamide1Unknown Status1
DB00091Cyclosporine1Completed2
DB00987Cytarabine1Active Not Recruiting6
DB00987Cytarabine1Completed9
DB00987Cytarabine1Not Yet Recruiting1
DB00987Cytarabine1Recruiting15
DB00987Cytarabine1Terminated3
DB00987Cytarabine1Withdrawn3
DB01254Dasatinib1Recruiting1
DB00694Daunorubicin1Active Not Recruiting4
DB00694Daunorubicin1Completed2
DB00694Daunorubicin1Recruiting6
DB00694Daunorubicin1Terminated1
DB01262Decitabine1Active Not Recruiting5
DB01262Decitabine1Completed8
DB01262Decitabine1Not Yet Recruiting1
DB01262Decitabine1Recruiting5
DB01262Decitabine1Terminated1
DB01609Deferasirox1Not Yet Recruiting1
DB01234Dexamethasone1Completed1
DB01234Dexamethasone1Recruiting1
DB11841Entinostat1Active Not Recruiting1
DB12121Entospletinib1Recruiting1
DB00773Etoposide1Completed2
DB00773Etoposide1Recruiting1
DB00773Etoposide1Terminated2
DB01590Everolimus1Active Not Recruiting1
DB01590Everolimus1Completed1
DB01590Everolimus1Unknown Status1
DB11680Ficlatuzumab1Recruiting1
DB00099Filgrastim1Active Not Recruiting2
DB00099Filgrastim1Completed1
DB01073Fludarabine1Active Not Recruiting2
DB01073Fludarabine1Completed1
DB01073Fludarabine1Recruiting6
DB01073Fludarabine1Withdrawn1
DB12047Ganetespib1Completed2
DB00056Gemtuzumab ozogamicin1Terminated2
DB12141Gilteritinib1Recruiting2
DB11978Glasdegib1Recruiting1
DB11918Guadecitabine1Active Not Recruiting1
DB00741Hydrocortisone1Completed2
DB00741Hydrocortisone1Recruiting2
DB01177Idarubicin1Active Not Recruiting1
DB01177Idarubicin1Recruiting6
DB01177Idarubicin1Withdrawn2
DB09054Idelalisib1Completed1
DB11997Interleukin-71Completed1
DB06186Ipilimumab1Recruiting1
DB09570Ixazomib1Recruiting1
DB00125L-Arginine1Completed1
DB00480Lenalidomide1Completed2
DB00480Lenalidomide1Recruiting3
DB00480Lenalidomide1Terminated2
DB00650Leucovorin1Recruiting1
DB11740MK-17751Active Not Recruiting1
DB01042Melphalan1Active Not Recruiting1
DB00563Methotrexate1Completed3
DB00563Methotrexate1Recruiting3
DB00563Methotrexate1Terminated1
DB06595Midostaurin1Active Not Recruiting1
DB06595Midostaurin1Completed4
DB01204Mitoxantrone1Active Not Recruiting1
DB01204Mitoxantrone1Completed2
DB01204Mitoxantrone1Terminated2
DB00688Mycophenolate mofetil1Completed1
DB00688Mycophenolate mofetil1Terminated1
DB09035Nivolumab1Not Yet Recruiting1
DB09073Palbociclib1Recruiting1
DB06603Panobinostat1Active Not Recruiting2
DB06603Panobinostat1Completed3
DB06603Panobinostat1Recruiting1
DB00019Pegfilgrastim1Withdrawn1
DB09037Pembrolizumab1Not Yet Recruiting1
DB12920Pinometostat1Completed2
DB06809Plerixafor1Active Not Recruiting3
DB06809Plerixafor1Completed2
DB06809Plerixafor1Terminated1
DB08910Pomalidomide1Recruiting1
DB12874Quizartinib1Active Not Recruiting1
DB05213Quizartinib1Completed2
DB12874Quizartinib1Completed1
DB08896Regorafenib1Not Yet Recruiting1
DB11942Selinexor1Active Not Recruiting2
DB11942Selinexor1Completed2
DB11942Selinexor1Recruiting1
DB01104Sertraline1Recruiting1
DB00877Sirolimus1Completed2
DB00398Sorafenib1Active Not Recruiting2
DB00398Sorafenib1Completed4
DB00398Sorafenib1Recruiting1
DB12756TAK-9011Completed1
DB00864Tacrolimus1Recruiting1
DB00864Tacrolimus1Terminated1
DB11760Talazoparib1Completed1
DB11941Tasisulam1Completed1
DB00853Temozolomide1Active Not Recruiting1
DB12226Terameprocol1Terminated1
DB00679Thioridazine1Completed1
DB00560Tigecycline1Completed1
DB06273Tocilizumab1Recruiting1
DB08911Trametinib1Completed1
DB00755Tretinoin1Completed1
DB00755Tretinoin1Recruiting1
DB11884Vadastuximab Talirine1Active Not Recruiting2
DB07232Veliparib1Active Not Recruiting1
DB11581Venetoclax1Active Not Recruiting1
DB11581Venetoclax1Recruiting2
DB12062Volasertib1Completed1
DB12062Volasertib1Withdrawn3
DB02546Vorinostat1Active Not Recruiting1
DB02546Vorinostat1Completed1
DB00399Zoledronic acid1Recruiting1
DB12746AKN-0281 / 2Terminated1
DB04974AP19031 / 2Recruiting1
DB11684APR-2461 / 2Recruiting1
DB05169AT92831 / 2Terminated1
DB00041Aldesleukin1 / 2Recruiting2
DB01143Amifostine1 / 2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)1 / 2Unknown Status1
DB01169Arsenic trioxide1 / 2Recruiting1
DB11595Atezolizumab1 / 2Not Yet Recruiting1
DB11945Avelumab1 / 2Recruiting1
DB00928Azacitidine1 / 2Completed3
DB00928Azacitidine1 / 2Recruiting7
DB00928Azacitidine1 / 2Withdrawn1
DB05015Belinostat1 / 2Completed1
DB06769Bendamustine1 / 2Recruiting1
DB06769Bendamustine1 / 2Terminated1
DB00188Bortezomib1 / 2Completed2
DB00188Bortezomib1 / 2Recruiting1
DB01008Busulfan1 / 2Recruiting2
DB01008Busulfan1 / 2Unknown Status1
DB00520Caspofungin1 / 2Not Yet Recruiting1
DB00493Cefotaxime1 / 2Active Not Recruiting1
DB00537Ciprofloxacin1 / 2Recruiting1
DB00242Cladribine1 / 2Recruiting2
DB00631Clofarabine1 / 2Active Not Recruiting1
DB00631Clofarabine1 / 2Completed1
DB06189Clofarabine1 / 2Completed1
DB00631Clofarabine1 / 2Unknown Status1
DB05239Cobimetinib1 / 2Recruiting1
DB00531Cyclophosphamide1 / 2Active Not Recruiting1
DB00531Cyclophosphamide1 / 2Recruiting2
DB00531Cyclophosphamide1 / 2Withdrawn1
DB00987Cytarabine1 / 2Active Not Recruiting2
DB00987Cytarabine1 / 2Completed8
DB00987Cytarabine1 / 2Recruiting15
DB00987Cytarabine1 / 2Terminated2
DB00987Cytarabine1 / 2Unknown Status2
DB01254Dasatinib1 / 2Completed1
DB00694Daunorubicin1 / 2Completed2
DB00694Daunorubicin1 / 2Recruiting1
DB01262Decitabine1 / 2Completed2
DB01262Decitabine1 / 2Not Yet Recruiting2
DB01262Decitabine1 / 2Recruiting4
DB01262Decitabine1 / 2Unknown Status1
DB01234Dexamethasone1 / 2Recruiting1
DB00390Digoxin1 / 2Not Yet Recruiting1
DB11687E-62011 / 2Terminated1
DB05494Elacytarabine1 / 2Completed1
DB06210Eltrombopag1 / 2Terminated1
DB13874Enasidenib1 / 2Recruiting1
DB12121Entospletinib1 / 2Recruiting1
DB00773Etoposide1 / 2Active Not Recruiting1
DB00773Etoposide1 / 2Completed1
DB00773Etoposide1 / 2Recruiting2
DB01590Everolimus1 / 2Completed1
DB00099Filgrastim1 / 2Active Not Recruiting1
DB00099Filgrastim1 / 2Completed2
DB00099Filgrastim1 / 2Recruiting3
DB01073Fludarabine1 / 2Active Not Recruiting2
DB01073Fludarabine1 / 2Recruiting5
DB01073Fludarabine1 / 2Terminated1
DB01073Fludarabine1 / 2Unknown Status1
DB01073Fludarabine1 / 2Withdrawn1
DB00695Furosemide1 / 2Recruiting1
DB12047Ganetespib1 / 2Completed1
DB00056Gemtuzumab ozogamicin1 / 2Active Not Recruiting1
DB00056Gemtuzumab ozogamicin1 / 2Completed1
DB00056Gemtuzumab ozogamicin1 / 2Unknown Status1
DB12141Gilteritinib1 / 2Active Not Recruiting2
DB11918Guadecitabine1 / 2Active Not Recruiting1
DB01177Idarubicin1 / 2Active Not Recruiting1
DB01177Idarubicin1 / 2Completed2
DB01177Idarubicin1 / 2Recruiting6
DB01177Idarubicin1 / 2Unknown Status1
DB12325Idasanutlin1 / 2Recruiting1
DB12827Indoximod1 / 2Recruiting1
DB01167Itraconazole1 / 2Completed1
DB12324Laromustine1 / 2Unknown Status1
DB00480Lenalidomide1 / 2Active Not Recruiting1
DB00480Lenalidomide1 / 2Completed2
DB00227Lovastatin1 / 2Recruiting1
DB01042Melphalan1 / 2Active Not Recruiting1
DB00563Methotrexate1 / 2Recruiting1
DB00959Methylprednisolone1 / 2Recruiting1
DB06595Midostaurin1 / 2Completed2
DB06595Midostaurin1 / 2Terminated1
DB01204Mitoxantrone1 / 2Active Not Recruiting1
DB01204Mitoxantrone1 / 2Completed1
DB01204Mitoxantrone1 / 2Recruiting2
DB00688Mycophenolate mofetil1 / 2Active Not Recruiting1
DB04868Nilotinib1 / 2Completed1
DB04868Nilotinib1 / 2Terminated1
DB09079Nintedanib1 / 2Unknown Status1
DB09035Nivolumab1 / 2Recruiting1
DB04865Omacetaxine mepesuccinate1 / 2Recruiting1
DB00526Oxaliplatin1 / 2Terminated1
DB09073Palbociclib1 / 2Recruiting1
DB06603Panobinostat1 / 2Active Not Recruiting1
DB06603Panobinostat1 / 2Completed1
DB00019Pegfilgrastim1 / 2Completed1
DB00019Pegfilgrastim1 / 2Recruiting1
DB00008Peginterferon alfa-2a1 / 2Recruiting1
DB06809Plerixafor1 / 2Active Not Recruiting1
DB06809Plerixafor1 / 2Completed3
DB06809Plerixafor1 / 2Recruiting1
DB12411R-4281 / 2Recruiting1
DB00811Ribavirin1 / 2Completed1
DB12146Rigosertib1 / 2Completed1
DB12146Rigosertib1 / 2Recruiting1
DB11942Selinexor1 / 2Recruiting2
DB00398Sorafenib1 / 2Completed1
DB00398Sorafenib1 / 2Recruiting4
DB00421Spironolactone1 / 2Recruiting1
DB01268Sunitinib1 / 2Completed1
DB00864Tacrolimus1 / 2Active Not Recruiting1
DB00864Tacrolimus1 / 2Recruiting1
DB11760Talazoparib1 / 2Not Yet Recruiting1
DB01520Tenocyclidine1 / 2Recruiting1
DB05745Tosedostat1 / 2Completed1
DB11781Tosedostat1 / 2Completed1
DB00752Tranylcypromine1 / 2Recruiting2
DB00755Tretinoin1 / 2Recruiting3
DB11884Vadastuximab Talirine1 / 2Active Not Recruiting1
DB11581Venetoclax1 / 2Recruiting2
DB02546Vorinostat1 / 2Recruiting1
DB04998AGRO1002Terminated1
DB01281Abatacept2Completed1
DB11617Aclarubicin2Recruiting2
DB00041Aldesleukin2Completed1
DB00041Aldesleukin2Recruiting1
DB00041Aldesleukin2Terminated1
DB00087Alemtuzumab2Active Not Recruiting1
DB00087Alemtuzumab2Recruiting2
DB05220Alisertib2Active Not Recruiting1
DB03496Alvocidib2Recruiting1
DB05022Amonafide2Unknown Status1
DB00681Amphotericin B2Unknown Status1
DB00362Anidulafungin2Completed1
DB09312Antilymphocyte immunoglobulin (horse)2Completed1
DB09312Antilymphocyte immunoglobulin (horse)2Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)2Active Not Recruiting2
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Recruiting3
DB00098Antithymocyte immunoglobulin (rabbit)2Terminated3
DB00673Aprepitant2Completed1
DB01169Arsenic trioxide2Completed1
DB01169Arsenic trioxide2Recruiting1
DB00023Asparaginase2Terminated1
DB08886Asparaginase Erwinia chrysanthemi2Recruiting1
DB06626Axitinib2Completed1
DB00928Azacitidine2Active Not Recruiting6
DB00928Azacitidine2Completed7
DB00928Azacitidine2Enrolling by Invitation1
DB00928Azacitidine2Not Yet Recruiting1
DB00928Azacitidine2Recruiting9
DB00928Azacitidine2Terminated4
DB00928Azacitidine2Unknown Status2
DB00928Azacitidine2Withdrawn1
DB00307Bexarotene2Active Not Recruiting1
DB09052Blinatumomab2Recruiting1
DB00188Bortezomib2Active Not Recruiting1
DB00188Bortezomib2Terminated1
DB08870Brentuximab vedotin2Completed1
DB01008Busulfan2Active Not Recruiting3
DB01008Busulfan2Completed3
DB01008Busulfan2Recruiting6
DB01008Busulfan2Terminated1
DB12476CPG-528522Terminated1
DB12109CPI-6132Withdrawn1
DB01197Captopril2Recruiting1
DB00958Carboplatin2Not Yet Recruiting1
DB00958Carboplatin2Recruiting1
DB00493Cefotaxime2Not Yet Recruiting1
DB00493Cefotaxime2Recruiting4
DB00493Cefotaxime2Suspended1
DB00169Cholecalciferol2Recruiting1
DB00242Cladribine2Recruiting3
DB00631Clofarabine2Completed10
DB06189Clofarabine2Completed6
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DB01234Dexamethasone2Terminated1
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DB12021Dinaciclib2Terminated1
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DB09560Filgrastim2Completed1
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DB01073Fludarabine2Suspended1
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DB00056Gemtuzumab ozogamicin2Active Not Recruiting1
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DB00688Mycophenolate mofetil2Active Not Recruiting4
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DB05745Tosedostat2Unknown Status1
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DB07232Veliparib2Not Yet Recruiting1
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DB00126Vitamin C2Suspended1
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DB00928Azacitidine2 / 3Not Yet Recruiting1
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DB11747Barasertib2 / 3Completed1
DB01008Busulfan2 / 3Recruiting1
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DB00531Cyclophosphamide2 / 3Recruiting1
DB00531Cyclophosphamide2 / 3Terminated1
DB00091Cyclosporine2 / 3Recruiting1
DB00987Cytarabine2 / 3Completed1
DB00987Cytarabine2 / 3Not Yet Recruiting1
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DB00694Daunorubicin2 / 3Recruiting1
DB01262Decitabine2 / 3Not Yet Recruiting1
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DB00099Filgrastim2 / 3Recruiting1
DB00056Gemtuzumab ozogamicin2 / 3Recruiting1
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DB01177Idarubicin2 / 3Recruiting1
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DB00584Enalapril3Completed1
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DB01073Fludarabine3Recruiting4
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DB11918Guadecitabine3Active Not Recruiting1
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DB01177Idarubicin3Completed3
DB01177Idarubicin3Recruiting3
DB12325Idasanutlin3Recruiting1
DB00128L-Aspartic Acid3Active Not Recruiting1
DB13144Lenograstim3Recruiting1
DB01206Lomustine3Completed1
DB01042Melphalan3Completed1
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DB01233Metoclopramide3Recruiting1
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DB12874Quizartinib3Recruiting1
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DB00877Sirolimus3Completed1
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DB00987Cytarabine4Unknown Status3
DB00694Daunorubicin4Active Not Recruiting1
DB01262Decitabine4Active Not Recruiting1
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DB01073Fludarabine4Recruiting1
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DB05381Histamine4Completed1
DB11320Histamine4Completed1
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DB01263Posaconazole4Recruiting1
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DB00437AllopurinolNot AvailableRecruiting1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB00928AzacitidineNot AvailableActive Not Recruiting1
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DB01008BusulfanNot AvailableRecruiting2
DB01008BusulfanNot AvailableTerminated1
DB00631ClofarabineNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableCompleted1
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DB00091CyclosporineNot AvailableRecruiting2
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DB00987CytarabineNot AvailableTerminated1
DB01254DasatinibNot AvailableRecruiting1
DB00694DaunorubicinNot AvailableRecruiting1
DB01262DecitabineNot AvailableNot Yet Recruiting1
DB00746DeferoxamineNot AvailableTerminated1
DB00773EtoposideNot AvailableCompleted2
DB00773EtoposideNot AvailableRecruiting1
DB00099FilgrastimNot AvailableRecruiting1
DB01073FludarabineNot AvailableCompleted2
DB01073FludarabineNot AvailableRecruiting2
DB00056Gemtuzumab ozogamicinNot AvailableNot Yet Recruiting1
DB12141GilteritinibNot AvailableAvailable2
DB01177IdarubicinNot AvailableRecruiting1
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DB00480LenalidomideNot AvailableCompleted1
DB01202LevetiracetamNot AvailableRecruiting1
DB01042MelphalanNot AvailableCompleted1
DB01204MitoxantroneNot AvailableCompleted1
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DB00688Mycophenolate mofetilNot AvailableRecruiting2
DB00019PegfilgrastimNot AvailableTerminated1
DB06809PlerixaforNot AvailableCompleted1
DB00877SirolimusNot AvailableCompleted1
DB00864TacrolimusNot AvailableRecruiting1
DB11581VenetoclaxNot AvailableAvailable1
DB11999VosaroxinNot AvailableTerminated1