Ocular Hypertension Completed Phase 4 Trials for Brimonidine (DB00484)

Also known as: Intraocular pressure raised / Ocular Hypertension (OHT) / Hypertension Ocular / Hypertension, Ocular / Intraocular pressure high / Intraocular hypertension / Ocular Hypertension (OH) / Elevated intraoccular pressure / Intraocular pressure increased / IOP increased / Raised IOP / Ocular tension increased / Tension ocular increased / Pressure intraocular increased / Increased intraocular pressure

IndicationStatusPhase
DBCOND0074237 (Ocular Hypertension)Completed4
clinicaltrials.gov IdentifierTitlePurposeDrugs
NCT03192826Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser CapsulotomyPrevention
NCT02419508SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)Treatment
NCT00698945Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG)Treatment
NCT02003534A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular HypertensionTreatment
NCT00822055Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular HypertensionTreatment
NCT00811564An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension SubjectsTreatment
NCT00735449Comparing Efficacy and Safety of Combigan With Timolol Adjunctive to Xalatan in Glaucoma or Ocular Hypertension SubjectsTreatment
NCT01978600Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular HypertensionTreatment
NCT01937312Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin AnalogueTreatment
NCT01937299Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z®Treatment
NCT01525173A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular HypertensionTreatment
NCT0045779524-hour IOP-lowering Effect of Brimonidine 0.1%Treatment
NCT00675207Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin AnalogsTreatment
NCT01170884Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan®Treatment
NCT00440141Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%Treatment