Neutropenia, Febrile

Also known as: Febrile neutropenia / Neutropenic fever

DrugDrug NameDrug Description
DB00681Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
DB00355AztreonamA beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria.
DB00520CaspofunginAn echinocandin used to treat a variety of fungal infections.
DB01413CefepimeA fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections.
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB00099FilgrastimA form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy.
DB13200LipegfilgrastimA medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy.
DrugDrug NameTargetType
DB00681Amphotericin BErgosteroltarget
DB00681Amphotericin BCytochrome P450 3A4enzyme
DB00355AztreonamPenicillin-binding protein 3target
DB00355AztreonamBeta-lactamasetarget
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginP-glycoprotein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB01413CefepimeSolute carrier family 22 member 5transporter
DB01413CefepimeSolute carrier family 15 member 1transporter
DB01413CefepimeSolute carrier family 15 member 2transporter
DB01413CefepimePenicillin-binding protein 2target
DB01413CefepimePeptidoglycan synthase FtsItarget
DB01413CefepimePenicillin-binding protein 3target
DB01413CefepimePenicillin-binding protein 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB00099FilgrastimGranulocyte colony-stimulating factor receptortarget
DB00099FilgrastimNeutrophil elastasetarget
DB13200LipegfilgrastimGranulocyte colony-stimulating factor receptortarget
DrugDrug NamePhaseStatusCount
DB14336Angelica sinensis root2Completed1
DB01413Cefepime2Recruiting1
DB01413Cefepime2Terminated1
DB00531Cyclophosphamide2Completed1
DB01248Docetaxel2Completed1
DB12592EC-182Recruiting1
DB00445Epirubicin2Completed1
DB00099Filgrastim2Completed1
DB00099Filgrastim2Recruiting1
DB01167Itraconazole2Completed1
DB00601Linezolid2Terminated1
DB00760Meropenem2Terminated1
DB01141Micafungin2Completed1
DB00019Pegfilgrastim2Recruiting1
DB00319Piperacillin2Recruiting1
DB00319Piperacillin2Terminated1
DB01606Tazobactam2Recruiting1
DB01606Tazobactam2Terminated1
DB00512Vancomycin2Terminated1
DB01413Cefepime3Completed1
DB00537Ciprofloxacin3Completed1
DB00080Daptomycin3Terminated1
DB00099Filgrastim3Recruiting1
DB00601Linezolid3Completed1
DB00019Pegfilgrastim3Completed1
DB00512Vancomycin3Completed1
DB00681Amphotericin B4Terminated1
DB01413Cefepime4Completed1
DB01413Cefepime4Recruiting1
DB00438Ceftazidime4Completed1
DB00438Ceftazidime4Not Yet Recruiting1
DB01597Cilastatin4Completed1
DB06211Doripenem4Completed1
DB00099Filgrastim4Recruiting1
DB01598Imipenem4Completed1
DB00760Meropenem4Completed1
DB00760Meropenem4Not Yet Recruiting1
DB00760Meropenem4Recruiting1
DB00319Piperacillin4Not Yet Recruiting1
DB00319Piperacillin4Recruiting1
DB01606Tazobactam4Not Yet Recruiting1
DB01606Tazobactam4Recruiting1
DB06149Teicoplanin4Completed1
DB00512Vancomycin4Completed1
DB00512Vancomycin4Not Yet Recruiting1
DB00681Amphotericin BNot AvailableCompleted1
DB00760MeropenemNot AvailableCompleted1
DB06149TeicoplaninNot AvailableCompleted1
DB00512VancomycinNot AvailableCompleted1