Heart Failure, Unspecified

Also known as: HEART FAILURE / Heart Failure (HF) / Heart failures / Cardiac Insufficiency / Weak heart / Failure heart / Heart failure (NOS) / Cardiac failure / Cardiac failure NOS / Cardiac failure (NOS) / Insufficiency cardiac / Cardiac function failure / Cardiac function failed / Heart insufficiency

DrugDrug NameDrug Description
DB00335AtenololA cardioselective beta-adrenergic blocker possessing properties and potency similar to propranolol, but without a negative inotropic effect.
DB00542BenazeprilBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.
DB00612BisoprololBisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Bisoprolol is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At lower doses (less than 20 mg daily), bisoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, bisoprolol does not exhibit membrane-stabilizing or sympathomimetic activity. Bisoprolol possesses a single chiral centre and is administered as a racemic mixture. Only l-bisoprolol exhibits significant β-blocking activity.
DB00887BumetanideA sulfamyl diuretic. [PubChem]
DB01197CaptoprilCaptopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
DB09477EnalaprilatEnalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume. Enalaprilat was originally created to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and left a metallic taste in the mouth. Removal of the problematic thiol group from captopril resulted in enalaprilat, which was then modified further with an ester to create the orally available pro-drug enalapril. Enalaprilat is poorly orally available and is therefore only available as an intravenous injection for the treatment of hypertension when oral therapy is not possible.
DB00492FosinoprilFosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB01275HydralazineA direct-acting vasodilator that is used as an antihypertensive agent.
DB00808IndapamideA benzamide-sulfonamide-indole. It is called a thiazide-like diuretic but structure is different enough (lacking the thiazo-ring) so it is not clear that the mechanism is comparable. [PubChem]
DB00883Isosorbide dinitrateA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
DB00678LosartanLosartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.
DB04861NebivololNebivolol is a highly cardioselective vasodilatory beta1 receptor blocker used in treatment of hypertension. In most countries, this medication is available only by prescription. [Wikipedia]
DB00178RamiprilRamipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular events.
DB00966TelmisartanTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
DB00519TrandolaprilTrandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Trandolapril may be used to treat mild to moderate hypertension, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, as an adjunct treatment for congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00177ValsartanValsartan is an angiotensin-receptor blocker (ARB) that may be used to treat a variety of cardiac conditions including hypertension, diabetic nephropathy and heart failure. Valsartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Valsartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
DrugDrug NameTargetType
DB00335AtenololBeta-1 adrenergic receptortarget
DB00335AtenololMultidrug resistance protein 1transporter
DB00335AtenololBeta-2 adrenergic receptortarget
DB00335AtenololCytochrome P450 2D6enzyme
DB00335AtenololBile salt export pumptransporter
DB00542BenazeprilAngiotensin-converting enzymetarget
DB00542BenazeprilMethylenetetrahydrofolate reductaseenzyme
DB00542BenazeprilSolute carrier family 15 member 1transporter
DB00542BenazeprilSolute carrier family 15 member 2transporter
DB00612BisoprololBeta-1 adrenergic receptortarget
DB00612BisoprololBeta-2 adrenergic receptortarget
DB00612BisoprololCytochrome P450 2D6enzyme
DB00612BisoprololCytochrome P450 3A4enzyme
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilCytochrome P450 2D6enzyme
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilMultidrug resistance protein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB09477EnalaprilatAngiotensin-converting enzymetarget
DB09477EnalaprilatB1 bradykinin receptortarget
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB01275HydralazineMembrane primary amine oxidasetarget
DB01275HydralazineProlyl 4-hydroxylase subunit alpha-1target
DB01275HydralazineCytochrome P450 3A4enzyme
DB00808IndapamideCytochrome P450 3A4enzyme
DB00808IndapamideSolute carrier family 12 member 3target
DB00883Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
DB00883Isosorbide dinitrateCytochrome P450 3A4enzyme
DB00883Isosorbide dinitrateCytochrome P450 2E1enzyme
DB00678LosartanType-1 angiotensin II receptortarget
DB00678LosartanCytochrome P450 3A4enzyme
DB00678LosartanCytochrome P450 2C9enzyme
DB00678LosartanCytochrome P450 2C8enzyme
DB00678LosartanMultidrug resistance protein 1transporter
DB00678LosartanSolute carrier family 22 member 6transporter
DB00678LosartanUDP-glucuronosyltransferase 1-1enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-3enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-10enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B7enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B17enzyme
DB00678LosartanCytochrome P450 1A2enzyme
DB00678LosartanCytochrome P450 2C19enzyme
DB00678LosartanSerum albumincarrier
DB00678LosartanSolute carrier family 22 member 12transporter
DB00678LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
DB00678LosartanBile salt export pumptransporter
DB04861NebivololBeta-1 adrenergic receptortarget
DB04861NebivololCytochrome P450 2D6enzyme
DB04861NebivololBeta-2 adrenergic receptortarget
DB00178RamiprilAngiotensin-converting enzymetarget
DB00178RamiprilSolute carrier family 15 member 1transporter
DB00178RamiprilSolute carrier family 15 member 2transporter
DB00178RamiprilCholinesteraseenzyme
DB00178RamiprilB1 bradykinin receptortarget
DB00966TelmisartanType-1 angiotensin II receptortarget
DB00966TelmisartanPeroxisome proliferator-activated receptor gammatarget
DB00966TelmisartanMultidrug resistance protein 1transporter
DB00966TelmisartanCanalicular multispecific organic anion transporter 1transporter
DB00966TelmisartanATP-binding cassette sub-family G member 2transporter
DB00966TelmisartanCytochrome P450 2C19enzyme
DB00966TelmisartanBile salt export pumptransporter
DB00519TrandolaprilAngiotensin-converting enzymetarget
DB00519TrandolaprilSolute carrier family 15 member 1transporter
DB00519TrandolaprilSolute carrier family 15 member 2transporter
DB00519TrandolaprilLiver carboxylesterase 1enzyme
DB00177ValsartanType-1 angiotensin II receptortarget
DB00177ValsartanCytochrome P450 2C9enzyme
DB00177ValsartanSolute carrier organic anion transporter family member 1B3transporter
DB00177ValsartanSolute carrier organic anion transporter family member 1B1transporter
DB00177ValsartanSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB12054BQ-1230Recruiting1
DB11121Chloroxylenol0Unknown Status1
DB00641Simvastatin0Completed1
DB00641Simvastatin0Unknown Status1
DB00126Ascorbic acid1Recruiting1
DB12054BQ-1231Recruiting1
DB09061Cannabidiol1Not Yet Recruiting1
DB11777Cenderitide1Completed1
DB11777Cenderitide1Withdrawn2
DB01407Clenbuterol1Terminated1
DB11981Elamipretide1Withdrawn1
DB00584Enalapril1Unknown Status1
DB00950Fexofenadine1Recruiting1
DB00695Furosemide1Terminated1
DB12841Glial growth factor 21Completed1
DB01275Hydralazine1Completed1
DB00028Immune Globulin Human1Unknown Status1
DB00883Isosorbide dinitrate1Completed1
DB06157Istaroxime1Withdrawn1
DB11968MK-71451Terminated1
DB00683Midazolam1Completed1
DB05063Mitoquinone1Recruiting1
DB14049Nitrate1Recruiting1
DB11816Omecamtiv Mecarbil1Completed1
DB00692Phentolamine1Recruiting1
DB00863Ranitidine1Recruiting1
DB00360Sapropterin1Recruiting1
DB00421Spironolactone1Completed1
DB12199TRV-1200271Completed1
DB00214Torasemide1Terminated1
DB01593Zinc1Completed1
DB00026Anakinra1 / 2Completed2
DB11777Cenderitide1 / 2Completed1
DB11121Chloroxylenol1 / 2Completed1
DB11574Elbasvir1 / 2Recruiting1
DB00695Furosemide1 / 2Completed2
DB11575Grazoprevir1 / 2Recruiting1
DB01277Mecasermin1 / 2Completed1
DB00235Milrinone1 / 2Active Not Recruiting1
DB00235Milrinone1 / 2Completed1
DB04899Nesiritide1 / 2Completed1
DB04899Nesiritide1 / 2Enrolling by Invitation1
DB11829Ruboxistaurin1 / 2Recruiting1
DB00203Sildenafil1 / 2Enrolling by Invitation1
DB09153Sodium Chloride1 / 2Completed1
DB12199TRV-1200271 / 2Completed1
DB12497Alagebrium2Completed1
DB09026Aliskiren2Completed2
DB09026Aliskiren2Terminated1
DB00437Allopurinol2Completed1
DB00026Anakinra2Completed1
DB01076Atorvastatin2Not Yet Recruiting1
DB01076Atorvastatin2Recruiting1
DB00612Bisoprolol2Terminated1
DB00796Candesartan cilexetil2Completed1
DB01136Carvedilol2Recruiting1
DB11777Cenderitide2Completed1
DB11121Chloroxylenol2Active Not Recruiting1
DB11121Chloroxylenol2Completed3
DB11121Chloroxylenol2Recruiting1
DB00169Cholecalciferol2Completed1
DB00012Darbepoetin alfa2Completed1
DB00937Diethylpropion2Recruiting1
DB00254Doxycycline2Not Yet Recruiting1
DB11981Elamipretide2Active Not Recruiting1
DB11981Elamipretide2Completed1
DB09038Empagliflozin2Enrolling by Invitation1
DB00700Eplerenone2Completed2
DB11827Ertugliflozin2Not Yet Recruiting1
DB00695Furosemide2Completed1
DB01020Isosorbide Mononitrate2Completed1
DB00883Isosorbide dinitrate2Active Not Recruiting1
DB06157Istaroxime2Completed1
DB06157Istaroxime2Withdrawn1
DB00922Levosimendan2Completed2
DB01065Melatonin2Withdrawn1
DB00331Metformin2Not Yet Recruiting2
DB00264Metoprolol2Completed1
DB00235Milrinone2Not Yet Recruiting1
DB08893Mirabegron2Not Yet Recruiting1
DB13138Neladenoson bialanate2Completed4
DB04899Nesiritide2Completed1
DB04899Nesiritide2Terminated1
DB14049Nitrate2Recruiting1
DB12529Nitrite2Recruiting2
DB00727Nitroglycerin2Recruiting1
DB09112Nitrous acid2Completed2
DB09112Nitrous acid2Recruiting3
DB05634Omecamtiv Mecarbil2Completed3
DB11816Omecamtiv Mecarbil2Completed2
DB05634Omecamtiv Mecarbil2Terminated1
DB11816Omecamtiv Mecarbil2Withdrawn1
DB09140Oxygen2Completed1
DB09263Patiromer2Completed2
DB12821Perflubutane2Recruiting1
DB00556Perflutren2Recruiting1
DB00761Potassium Chloride2Completed1
DB00761Potassium Chloride2Recruiting1
DB11090Potassium nitrate2Completed1
DB11090Potassium nitrate2Recruiting1
DB00545Pyridostigmine2Completed1
DB11194Pyruvic acid2Completed1
DB13107QGC-0012Recruiting1
DB00178Ramipril2Completed1
DB00243Ranolazine2Terminated1
DB12670Rolofylline2Completed1
DB01098Rosuvastatin2Completed1
DB09292Sacubitril2Completed1
DB09292Sacubitril2Recruiting1
DB00203Sildenafil2Completed1
DB09153Sodium Chloride2Completed1
DB09153Sodium Chloride2Not Yet Recruiting1
DB09153Sodium Chloride2Recruiting1
DB14048Sodium zirconium cyclosilicate2Recruiting1
DB08934Sofosbuvir2Recruiting1
DB00052Somatotropin2Completed1
DB06417Somatotropin2Completed1
DB00421Spironolactone2Completed4
DB00624Testosterone2Terminated2
DB00152Thiamine2Completed1
DB09499Thiosulfuric acid2Not Yet Recruiting1
DB12569Tonapofylline2Terminated1
DB09270Ubidecarenone2Not Yet Recruiting1
DB11340Ubiquinol2Not Yet Recruiting1
DB00177Valsartan2Recruiting1
DB11613Velpatasvir2Recruiting1
DB00381Amlodipine2 / 3Completed1
DB00026Anakinra2 / 3Completed2
DB00612Bisoprolol2 / 3Completed1
DB11121Chloroxylenol2 / 3Completed2
DB11121Chloroxylenol2 / 3Terminated1
DB00169Cholecalciferol2 / 3Unknown Status1
DB00841Dobutamine2 / 3Completed1
DB00988Dopamine2 / 3Completed1
DB00695Furosemide2 / 3Completed2
DB01275Hydralazine2 / 3Completed1
DB00583L-Carnitine2 / 3Completed2
DB00130L-Glutamine2 / 3Completed1
DB00331Metformin2 / 3Completed1
DB00563Methotrexate2 / 3Completed1
DB00727Nitroglycerin2 / 3Completed1
DB00635Prednisone2 / 3Recruiting1
DB00203Sildenafil2 / 3Completed1
DB00421Spironolactone2 / 3Recruiting1
DB00966Telmisartan2 / 3Completed1
DB00214Torasemide2 / 3Completed1
DB00819Acetazolamide3Terminated1
DB00945Acetylsalicylic acid3Completed1
DB09026Aliskiren3Completed1
DB00770Alprostadil3Suspended1
DB01118Amiodarone3Completed1
DB01118Amiodarone3Terminated1
DB00381Amlodipine3Completed1
DB00335Atenolol3Terminated1
DB00887Bumetanide3Withdrawn1
DB00490Buspirone3Terminated1
DB00796Candesartan cilexetil3Completed1
DB00796Candesartan cilexetil3Terminated1
DB12221Canrenone3Completed1
DB01136Carvedilol3Completed2
DB01136Carvedilol3Terminated1
DB11121Chloroxylenol3Completed2
DB11121Chloroxylenol3Recruiting1
DB00310Chlorthalidone3Completed1
DB00169Cholecalciferol3Completed1
DB04920Clevidipine3Completed1
DB00012Darbepoetin alfa3Completed1
DB00012Darbepoetin alfa3Terminated1
DB00343Diltiazem3Completed1
DB00343Diltiazem3Terminated1
DB00280Disopyramide3Terminated1
DB00204Dofetilide3Terminated1
DB00590Doxazosin3Completed1
DB09038Empagliflozin3Recruiting5
DB00584Enalapril3Completed2
DB00700Eplerenone3Active Not Recruiting1
DB00700Eplerenone3Completed2
DB00153Ergocalciferol3Active Not Recruiting1
DB00153Ergocalciferol3Completed1
DB08917Ferric Carboxymaltose3Recruiting1
DB08917Ferric Carboxymaltose3Terminated1
DB00695Furosemide3Recruiting2
DB00695Furosemide3Withdrawn1
DB05039Indacaterol3Recruiting1
DB09546Iobenguane sulfate I-1233Completed1
DB09546Iobenguane sulfate I-1233Recruiting1
DB00883Isosorbide dinitrate3Completed1
DB09083Ivabradine3Completed1
DB00922Levosimendan3Recruiting1
DB00922Levosimendan3Terminated1
DB00722Lisinopril3Completed1
DB00678Losartan3Completed1
DB00264Metoprolol3Terminated1
DB04861Nebivolol3Active Not Recruiting1
DB04899Nesiritide3Terminated1
DB00622Nicardipine3Completed1
DB00727Nitroglycerin3Completed1
DB00325Nitroprusside3Completed1
DB11816Omecamtiv Mecarbil3Recruiting1
DB11133Omega-3 fatty acids3Terminated1
DB09539Omega-3-acid ethyl esters3Terminated1
DB06715Potassium Iodide3Recruiting1
DB09418Potassium perchlorate3Recruiting1
DB00175Pravastatin3Completed1
DB00635Prednisone3Completed1
DB01035Procainamide3Terminated1
DB01182Propafenone3Terminated1
DB00243Ranolazine3Completed1
DB06228Rivaroxaban3Completed2
DB01098Rosuvastatin3Completed3
DB09292Sacubitril3Not Yet Recruiting1
DB09292Sacubitril3Recruiting1
DB00203Sildenafil3Active Not Recruiting1
DB00203Sildenafil3Completed3
DB00203Sildenafil3Recruiting1
DB09153Sodium Chloride3Recruiting2
DB09153Sodium Chloride3Terminated1
DB00489Sotalol3Terminated1
DB00421Spironolactone3Active Not Recruiting1
DB00421Spironolactone3Completed2
DB02772Sucrose3Not Yet Recruiting1
DB00820Tadalafil3Terminated1
DB00820Tadalafil3Withdrawn1
DB06212Tolvaptan3Completed2
DB00214Torasemide3Recruiting1
DB00177Valsartan3Not Yet Recruiting1
DB00177Valsartan3Recruiting1
DB00661Verapamil3Terminated1
DB11094Vitamin D3Active Not Recruiting1
DB11094Vitamin D3Completed1
DB00819Acetazolamide4Completed1
DB00945Acetylsalicylic acid4Active Not Recruiting1
DB00945Acetylsalicylic acid4Completed1
DB09026Aliskiren4Completed1
DB09026Aliskiren4Unknown Status1
DB00437Allopurinol4Completed1
DB01118Amiodarone4Active Not Recruiting1
DB01118Amiodarone4Recruiting1
DB01076Atorvastatin4Completed1
DB01076Atorvastatin4Recruiting1
DB12319Benzbromarone4Completed1
DB00612Bisoprolol4Completed1
DB00612Bisoprolol4Recruiting1
DB00887Bumetanide4Completed1
DB00796Candesartan cilexetil4Completed2
DB01197Captopril4Completed1
DB01136Carvedilol4Completed3
DB01136Carvedilol4Terminated1
DB01136Carvedilol4Withdrawn1
DB00880Chlorothiazide4Enrolling by Invitation2
DB11121Chloroxylenol4Completed1
DB11121Chloroxylenol4Recruiting1
DB00169Cholecalciferol4Terminated1
DB00575Clonidine4Completed1
DB00872Conivaptan4Completed1
DB00872Conivaptan4Withdrawn1
DB06292Dapagliflozin4Completed1
DB01234Dexamethasone4Recruiting1
DB09341Dextrose, unspecified form4Completed1
DB00390Digoxin4Completed1
DB00390Digoxin4Unknown Status1
DB00841Dobutamine4Recruiting1
DB00841Dobutamine4Suspended1
DB00841Dobutamine4Unknown Status1
DB09038Empagliflozin4Not Yet Recruiting1
DB09038Empagliflozin4Recruiting1
DB00584Enalapril4Completed1
DB00584Enalapril4Recruiting1
DB00584Enalapril4Unknown Status1
DB00700Eplerenone4Completed1
DB01240Epoprostenol4Completed1
DB00153Ergocalciferol4Completed1
DB00016Erythropoietin4Unknown Status1
DB08917Ferric Carboxymaltose4Completed1
DB08917Ferric Carboxymaltose4Recruiting3
DB08917Ferric Carboxymaltose4Withdrawn1
DB00158Folic Acid4Terminated1
DB00695Furosemide4Completed1
DB00695Furosemide4Recruiting1
DB01109Heparin4Recruiting1
DB01275Hydralazine4Recruiting1
DB00999Hydrochlorothiazide4Recruiting1
DB06704Iobenguane4Completed1
DB09546Iobenguane sulfate I-1234Completed1
DB01592Iron4Recruiting1
DB12208Iron isomaltoside 10004Recruiting1
DB09146Iron saccharate4Completed1
DB00883Isosorbide dinitrate4Recruiting1
DB09083Ivabradine4Active Not Recruiting1
DB09083Ivabradine4Completed1
DB09083Ivabradine4Not Yet Recruiting1
DB09083Ivabradine4Recruiting2
DB09083Ivabradine4Unknown Status2
DB09027Ledipasvir4Recruiting1
DB00922Levosimendan4Completed5
DB00922Levosimendan4Not Yet Recruiting1
DB00922Levosimendan4Withdrawn1
DB00451Levothyroxine4Completed2
DB00451Levothyroxine4Recruiting1
DB00722Lisinopril4Completed1
DB00678Losartan4Completed1
DB00678Losartan4Withdrawn1
DB00331Metformin4Recruiting1
DB00524Metolazone4Enrolling by Invitation2
DB00264Metoprolol4Completed1
DB00264Metoprolol4Withdrawn1
DB04861Nebivolol4Completed1
DB04899Nesiritide4Terminated1
DB00435Nitric Oxide4Completed1
DB00082Pegvisomant4Unknown Status1
DB00790Perindopril4Terminated1
DB00175Pravastatin4Terminated1
DB00635Prednisone4Completed1
DB00635Prednisone4Recruiting1
DB00178Ramipril4Completed1
DB09292Sacubitril4Recruiting6
DB06335Saxagliptin4Recruiting2
DB00203Sildenafil4Completed1
DB00203Sildenafil4Unknown Status1
DB01261Sitagliptin4Recruiting1
DB09153Sodium Chloride4Completed1
DB09517Sodium ferric gluconate complex4Completed1
DB08934Sofosbuvir4Recruiting1
DB00421Spironolactone4Active Not Recruiting1
DB00421Spironolactone4Completed3
DB00421Spironolactone4Withdrawn1
DB00566Succimer4Recruiting1
DB00864Tacrolimus4Recruiting1
DB00871Terbutaline4Completed1
DB00624Testosterone4Completed2
DB06212Tolvaptan4Completed3
DB06212Tolvaptan4Enrolling by Invitation1
DB06212Tolvaptan4Recruiting1
DB06212Tolvaptan4Withdrawn1
DB00214Torasemide4Enrolling by Invitation1
DB00214Torasemide4Recruiting1
DB00519Trandolapril4Completed1
DB00177Valsartan4Completed1
DB00177Valsartan4Recruiting5
DB11094Vitamin D4Completed1
DB00682Warfarin4Active Not Recruiting1
DB00425Zolpidem4Recruiting1
DB06361rsPSMA Vaccine4Completed1
DB00819AcetazolamideNot AvailableCompleted1
DB03128AcetylcholineNot AvailableCompleted1
DB09055AcipimoxNot AvailableCompleted1
DB00640AdenosineNot AvailableCompleted1
DB09026AliskirenNot AvailableUnknown Status1
DB01118AmiodaroneNot AvailableRecruiting1
DB00026AnakinraNot AvailableCompleted1
DB00126Ascorbic acidNot AvailableCompleted1
DB00612BisoprololNot AvailableUnknown Status1
DB12752BucindololNot AvailableUnknown Status1
DB08907CanagliflozinNot AvailableWithdrawn1
DB00796Candesartan cilexetilNot AvailableCompleted1
DB01136CarvedilolNot AvailableCompleted1
DB01136CarvedilolNot AvailableRecruiting1
DB01136CarvedilolNot AvailableUnknown Status1
DB00880ChlorothiazideNot AvailableRecruiting1
DB00169CholecalciferolNot AvailableCompleted1
DB00872ConivaptanNot AvailableUnknown Status1
DB00633DexmedetomidineNot AvailableCompleted1
DB00390DigoxinNot AvailableCompleted2
DB00841DobutamineNot AvailableNot Yet Recruiting1
DB09075EdoxabanNot AvailableRecruiting1
DB00153ErgocalciferolNot AvailableCompleted1
DB01276ExenatideNot AvailableUnknown Status1
DB00813FentanylNot AvailableRecruiting1
DB01195FlecainideNot AvailableRecruiting1
DB00695FurosemideNot AvailableRecruiting1
DB00695FurosemideNot AvailableTerminated1
DB00695FurosemideNot AvailableUnknown Status1
DB00986GlycopyrroniumNot AvailableCompleted1
DB01275HydralazineNot AvailableRecruiting1
DB01064IsoprenalineNot AvailableCompleted1
DB00883Isosorbide dinitrateNot AvailableRecruiting1
DB09083IvabradineNot AvailableCompleted2
DB09083IvabradineNot AvailableNot Yet Recruiting1
DB00125L-ArginineNot AvailableUnknown Status1
DB00922LevosimendanNot AvailableTerminated1
DB00281LidocaineNot AvailableRecruiting2
DB00279LiothyronineNot AvailableCompleted1
DB06655LiraglutideNot AvailableRecruiting2
DB00825MentholNot AvailableRecruiting1
DB00331MetforminNot AvailableCompleted2
DB00959MethylprednisoloneNot AvailableCompleted1
DB00264MetoprololNot AvailableUnknown Status1
DB00235MilrinoneNot AvailableRecruiting1
DB04861NebivololNot AvailableCompleted1
DB04861NebivololNot AvailableRecruiting1
DB04861NebivololNot AvailableUnknown Status1
DB04899NesiritideNot AvailableWithdrawn1
DB14049NitrateNot AvailableTerminated1
DB12529NitriteNot AvailableNot Yet Recruiting1
DB00325NitroprussideNot AvailableCompleted1
DB11133Omega-3 fatty acidsNot AvailableRecruiting1
DB00910ParicalcitolNot AvailableWithdrawn1
DB00388PhenylephrineNot AvailableCompleted1
DB00413PramipexoleNot AvailableCompleted1
DB01182PropafenoneNot AvailableRecruiting1
DB06228RivaroxabanNot AvailableRecruiting1
DB00296RopivacaineNot AvailableRecruiting1
DB09292SacubitrilNot AvailableActive Not Recruiting1
DB01001SalbutamolNot AvailableUnknown Status1
DB00360SapropterinNot AvailableRecruiting1
DB01104SertralineNot AvailableTerminated1
DB00641SimvastatinNot AvailableCompleted1
DB09153Sodium ChlorideNot AvailableCompleted1
DB09153Sodium ChlorideNot AvailableRecruiting1
DB09153Sodium ChlorideNot AvailableUnknown Status1
DB00489SotalolNot AvailableRecruiting1
DB00624TestosteroneNot AvailableUnknown Status1
DB00152ThiamineNot AvailableCompleted1
DB11079Trolamine salicylateNot AvailableRecruiting1
DB13033Urocortin-2Not AvailableCompleted1
DB00177ValsartanNot AvailableActive Not Recruiting1
DB11094Vitamin DNot AvailableCompleted1
DB00682WarfarinNot AvailableEnrolling by Invitation1
DB05875substance PNot AvailableCompleted1