Transient Ischaemic Attack (TIA)

Also known as: Transient Ischemic Attacks / Ischaemic Attack, Transient / Transient Ischaemic Attack / Ischemic Attack, Transient / TIA (Transient Ischemic Attack) / Transient Ischemic Attack (TIA) / Transient Ischemic Attack / TIA / Transient-ischaemic Attack / Transient ischaemic attacks / Spasm of cerebral artery

DrugDrug NameDrug Description
DB01418AcenocoumarolAcenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients on acenocoumarol are prohibited from giving blood.
DB00945Acetylsalicylic acidAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
DB00175PravastatinPravastatin is the 6-alpha-hydroxy acid form of [mevastatin].[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991.[L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained. The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation with _Streptomyces carbophilus_ to introduce the allylic 6-alcohol group.[T239]
DrugDrug NameTargetType
DB01418AcenocoumarolVitamin K epoxide reductase complex subunit 1target
DB01418AcenocoumarolCytochrome P450 2C9enzyme
DB01418AcenocoumarolCytochrome P450 1A2enzyme
DB01418AcenocoumarolSerum albumincarrier
DB01418AcenocoumarolAlpha-1-acid glycoprotein 1carrier
DB01418AcenocoumarolCytochrome P450 2C19enzyme
DB01418AcenocoumarolCytochrome P450 3A4enzyme
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidNuclear factor kappa b beta subunittarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00175Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00175PravastatinSolute carrier organic anion transporter family member 2B1transporter
DB00175PravastatinMultidrug resistance protein 1transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1A2transporter
DB00175PravastatinSolute carrier family 22 member 6transporter
DB00175PravastatinSolute carrier family 22 member 8transporter
DB00175PravastatinCanalicular multispecific organic anion transporter 1transporter
DB00175PravastatinSolute carrier family 22 member 11transporter
DB00175PravastatinATP-binding cassette sub-family G member 2transporter
DB00175PravastatinSolute carrier family 22 member 7transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B1transporter
DB00175PravastatinMonocarboxylate transporter 1transporter
DB00175PravastatinBile salt export pumptransporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB00945Acetylsalicylic acid2Completed1
DB00945Acetylsalicylic acid2Recruiting1
DB06695Dabigatran etexilate2Completed2
DB14489Ferrous succinate2Not Yet Recruiting1
DB00945Acetylsalicylic acid2 / 3Active Not Recruiting1
DB00945Acetylsalicylic acid2 / 3Completed1
DB00945Acetylsalicylic acid2 / 3Terminated1
DB00945Acetylsalicylic acid2 / 3Unknown Status2
DB06605Apixaban2 / 3Unknown Status1
DB00758Clopidogrel2 / 3Active Not Recruiting1
DB00758Clopidogrel2 / 3Completed1
DB00758Clopidogrel2 / 3Terminated1
DB00758Clopidogrel2 / 3Unknown Status1
DB00125L-Arginine2 / 3Terminated1
DB06228Rivaroxaban2 / 3Unknown Status1
DB00641Simvastatin2 / 3Completed1
DB08816Ticagrelor2 / 3Active Not Recruiting1
DB00945Acetylsalicylic acid3Completed2
DB00945Acetylsalicylic acid3Not Yet Recruiting1
DB06605Apixaban3Active Not Recruiting1
DB01076Atorvastatin3Not Yet Recruiting1
DB01394Colchicine3Not Yet Recruiting1
DB06655Liraglutide3Not Yet Recruiting1
DB06812Povidone-iodine3Not Yet Recruiting1
DB00682Warfarin3Active Not Recruiting1
DB00945Acetylsalicylic acid4Completed1
DB00945Acetylsalicylic acid4Unknown Status1
DB00758Clopidogrel4Not Yet Recruiting1
DB00945Acetylsalicylic acidNot AvailableActive Not Recruiting1
DB00945Acetylsalicylic acidNot AvailableNot Yet Recruiting1
DB00945Acetylsalicylic acidNot AvailableRecruiting1
DB00009AlteplaseNot AvailableTerminated1
DB00289AtomoxetineNot AvailableCompleted1
DB00758ClopidogrelNot AvailableActive Not Recruiting1
DB00758ClopidogrelNot AvailableNot Yet Recruiting1
DB00115CyanocobalaminNot AvailableWithdrawn1
DB06695Dabigatran etexilateNot AvailableCompleted1
DB00975DipyridamoleNot AvailableActive Not Recruiting1
DB00158Folic AcidNot AvailableWithdrawn1
DB00165PyridoxineNot AvailableWithdrawn1