Ewing's Sarcoma (ES)

Also known as: Ewing's Sarcoma / Ewing sarcoma / Ewings Sarcoma / Sarcoma, Ewing's / Sarcoma, Ewing / Sarcoma, Ewings / Ewing's sarcoma NOS / Ewing's sarcoma stage unspecified / Ewing's tumor / Ewing's tumour

DrugDrug NameDrug Description
DB00531CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
DB00970DactinomycinAn actinomycin used to treat a wide variety of cancers.
DB01248DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
DB00773EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
DB01181IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
DB00762IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
DB01030TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
DB00541VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DrugDrug NameTargetType
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB00970DactinomycinDNAtarget
DB00970DactinomycinSolute carrier family 22 member 5transporter
DB00970DactinomycinP-glycoprotein 1transporter
DB00970DactinomycinMultidrug resistance-associated protein 6transporter
DB00970DactinomycinMultidrug resistance-associated protein 1transporter
DB00970DactinomycinATP-binding cassette sub-family G member 2transporter
DB00970DactinomycinDNA topoisomerase 2target
DB01248DocetaxelApoptosis regulator Bcl-2target
DB01248DocetaxelTubulin beta-1 chaintarget
DB01248DocetaxelCytochrome P450 3A4enzyme
DB01248DocetaxelCytochrome P450 3A5enzyme
DB01248DocetaxelCytochrome P450 3A7enzyme
DB01248DocetaxelP-glycoprotein 1transporter
DB01248DocetaxelMultidrug resistance-associated protein 7transporter
DB01248DocetaxelCytochrome P450 1B1enzyme
DB01248DocetaxelMicrotubule-associated protein 2target
DB01248DocetaxelMicrotubule-associated protein 4target
DB01248DocetaxelMicrotubule-associated protein tautarget
DB01248DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DB01248DocetaxelSolute carrier family 22 member 7transporter
DB01248DocetaxelATP-binding cassette sub-family G member 2transporter
DB01248DocetaxelCanalicular multispecific organic anion transporter 1transporter
DB01248DocetaxelMultidrug resistance-associated protein 1transporter
DB01248DocetaxelNuclear receptor subfamily 1 group I member 2target
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideP-glycoprotein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideCytochrome P450 2B6enzyme
DB01181IfosfamideDNAtarget
DB01181IfosfamideCytochrome P450 3A4enzyme
DB01181IfosfamideCytochrome P450 3A5enzyme
DB01181IfosfamideCytochrome P450 2C9enzyme
DB01181IfosfamideCytochrome P450 2C8enzyme
DB01181IfosfamideCytochrome P450 2A6enzyme
DB01181IfosfamideCytochrome P450 2C19enzyme
DB01181IfosfamideCytochrome P450 2C18enzyme
DB01181IfosfamideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideNuclear receptor subfamily 1 group I member 2target
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanP-glycoprotein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DB01030TopotecanDNA topoisomerase I, mitochondrialtarget
DB01030TopotecanDNA topoisomerase 1target
DB01030TopotecanATP-binding cassette sub-family G member 2transporter
DB01030TopotecanP-glycoprotein 1transporter
DB01030TopotecanCytochrome P450 3A4enzyme
DB01030TopotecanDNAtarget
DB01030TopotecanMultidrug and toxin extrusion protein 1transporter
DB01030TopotecanMultidrug and toxin extrusion protein 2transporter
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineP-glycoprotein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB00087Alemtuzumab1Active Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)1Completed1
DB01008Busulfan1Active Not Recruiting2
DB01008Busulfan1Completed1
DB01008Busulfan1Withdrawn1
DB00531Cyclophosphamide1Completed3
DB00531Cyclophosphamide1Recruiting2
DB01262Decitabine1Completed1
DB00997Doxorubicin1Completed1
DB05847Doxorubicin1Recruiting1
DB00997Doxorubicin1Withdrawn1
DB15017Enoblituzumab1Completed1
DB00773Etoposide1Completed1
DB11685Figitumumab1Completed1
DB00099Filgrastim1Active Not Recruiting1
DB00099Filgrastim1Completed2
DB01073Fludarabine1Active Not Recruiting1
DB01073Fludarabine1Completed1
DB01073Fludarabine1Withdrawn1
DB01181Ifosfamide1Completed1
DB00762Irinotecan1Not Yet Recruiting1
DB00762Irinotecan1Recruiting4
DB09570Ixazomib1Not Yet Recruiting1
DB06599Lexatumumab1Terminated1
DB01042Melphalan1Active Not Recruiting2
DB01042Melphalan1Completed1
DB01042Melphalan1Withdrawn1
DB15244NM-404 I-1311Recruiting1
DB11793Niraparib1Recruiting1
DB09074Olaparib1Recruiting1
DB09073Palbociclib1Recruiting1
DB15069Pexastimogene devacirepvec1Completed1
DB13045Racotumomab1Completed1
DB05386Regramostim1Completed1
DB11942Selinexor1Not Yet Recruiting1
DB00641Simvastatin1Completed1
DB00877Sirolimus1Active Not Recruiting1
DB00877Sirolimus1Completed1
DB11760Talazoparib1Completed1
DB00853Temozolomide1Not Yet Recruiting1
DB00853Temozolomide1Recruiting3
DB01041Thalidomide1Recruiting1
DB01030Topotecan1Active Not Recruiting1
DB01030Topotecan1Completed1
DB05109Trabectedin1Not Yet Recruiting1
DB00541Vincristine1Completed1
DB02546Vorinostat1Recruiting1
DB00399Zoledronic acid1Recruiting1
DB00041Aldesleukin1 / 2Active Not Recruiting1
DB00531Cyclophosphamide1 / 2Unknown Status1
DB08871Eribulin1 / 2Recruiting1
DB00762Irinotecan1 / 2Recruiting1
DB09035Nivolumab1 / 2Recruiting1
DB01229Paclitaxel1 / 2Completed1
DB06810Plicamycin1 / 2Terminated1
DB06159Rubitecan1 / 2Completed1
DB00877Sirolimus1 / 2Recruiting1
DB00853Temozolomide1 / 2Completed1
DB01008Busulfan2Active Not Recruiting1
DB08875Cabozantinib2Recruiting1
DB00958Carboplatin2Completed1
DB00515Cisplatin2Completed1
DB09110Coenzyme M2Completed1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Terminated2
DB01254Dasatinib2Completed1
DB00380Dexrazoxane2Completed1
DB00380Dexrazoxane2Terminated1
DB00997Doxorubicin2Active Not Recruiting1
DB00997Doxorubicin2Completed1
DB00997Doxorubicin2Terminated2
DB08871Eribulin2Recruiting1
DB00530Erlotinib2Withdrawn1
DB00773Etoposide2Active Not Recruiting1
DB00773Etoposide2Completed1
DB00773Etoposide2Terminated1
DB06215Ferumoxytol2Completed1
DB00099Filgrastim2Completed2
DB12205Ganitumab2Recruiting1
DB00441Gemcitabine2Recruiting1
DB01645Genistein2Recruiting1
DB01181Ifosfamide2Active Not Recruiting1
DB01181Ifosfamide2Completed1
DB00224Indinavir2Completed1
DB00762Irinotecan2Active Not Recruiting2
DB00762Irinotecan2Terminated1
DB01042Melphalan2Active Not Recruiting1
DB01042Melphalan2Completed1
DB00134Methionine2Recruiting1
DB00553Methoxsalen2Not Yet Recruiting1
DB00765Metyrosine2Not Yet Recruiting1
DB09074Olaparib2Completed1
DB01229Paclitaxel2Recruiting2
DB09073Palbociclib2Recruiting1
DB00019Pegfilgrastim2Terminated1
DB00642Pemetrexed2Completed1
DB00252Phenytoin2Not Yet Recruiting1
DB15015Recombinant CD40-ligand2Completed1
DB05386Regramostim2Completed1
DB12976Robatumumab2Terminated1
DB00877Sirolimus2Not Yet Recruiting1
DB00853Temozolomide2Active Not Recruiting2
DB00853Temozolomide2Recruiting1
DB00853Temozolomide2Terminated1
DB00853Temozolomide2Withdrawn1
DB01030Topotecan2Completed1
DB08881Vemurafenib2Recruiting1
DB00541Vincristine2Active Not Recruiting1
DB00541Vincristine2Completed1
DB00541Vincristine2Recruiting1
DB00541Vincristine2Terminated2
DB12454Zalypsis2Completed1
DB00644Gonadorelin2 / 3Active Not Recruiting1
DB06825Triptorelin2 / 3Active Not Recruiting1
DB01008Busulfan3Active Not Recruiting1
DB01008Busulfan3Completed1
DB04690Camptothecin3Active Not Recruiting1
DB00531Cyclophosphamide3Active Not Recruiting1
DB00970Dactinomycin3Active Not Recruiting1
DB00997Doxorubicin3Active Not Recruiting1
DB00773Etoposide3Active Not Recruiting1
DB01181Ifosfamide3Active Not Recruiting1
DB00762Irinotecan3Active Not Recruiting1
DB01042Melphalan3Active Not Recruiting1
DB00853Temozolomide3Active Not Recruiting1
DB11678Treosulfan3Completed1
DB00541Vincristine3Active Not Recruiting1
DB00399Zoledronic acid3Completed1
DB00970DactinomycinNot AvailableUnknown Status1
DB12205GanitumabNot AvailableNo Longer Available1
DB01181IfosfamideNot AvailableUnknown Status1
DB00541VincristineNot AvailableUnknown Status1