Leukemia, Acute

Also known as: Acute Leukaemia / Leukemia acute / Acute Leukemia / Leukaemia, Acute / Acute Leukemias / Leukemia of unspecified cell type, acute / Acute leukaemia of unspecified cell type / Acute leukemia of unspecified cell type / Acute bilineal leukemia / Acute leukemia NOS / Leukaemia of unspecified cell type, acute / Leukaemia acute / Acute leukaemia NOS

DrugDrug NameDrug Description
DB00276AmsacrineA cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents.
DB01380Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DrugDrug NameTargetType
DB00276AmsacrineDNA topoisomerase 2-alphatarget
DB00276AmsacrineDNAtarget
DB00276AmsacrinePotassium voltage-gated channel subfamily H member 2target
DB00276AmsacrineP-glycoprotein 1transporter
DB00276AmsacrineAlpha-1-acid glycoprotein 1target
DB00276AmsacrineSerum albumintarget
DB01380Cortisone acetateGlucocorticoid receptortarget
DB01380Cortisone acetateCytochrome P450 3A4enzyme
DB01380Cortisone acetateCytochrome P450 3A5enzyme
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB00741Hydrocortisone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1target
DB00635PrednisoneCytochrome P450 3A5enzyme
DrugDrug NamePhaseStatusCount
DB05500AVN-9441Completed1
DB06769Bendamustine1Completed1
DB01008Busulfan1Recruiting1
DB00631Clofarabine1Completed1
DB06189Clofarabine1Completed1
DB00631Clofarabine1Terminated1
DB09110Coenzyme M1Recruiting1
DB00531Cyclophosphamide1Recruiting1
DB00531Cyclophosphamide1Terminated1
DB00987Cytarabine1Recruiting1
DB06179Darinaparsin1Completed1
DB01234Dexamethasone1Completed1
DB00997Doxorubicin1Recruiting1
DB00773Etoposide1Completed1
DB01073Fludarabine1Recruiting1
DB00741Hydrocortisone1Recruiting1
DB00762Irinotecan1Unknown Status1
DB00480Lenalidomide1Terminated1
DB11861Litronesib1Terminated1
DB12674Lurbinectedin1Completed1
DB01042Melphalan1Recruiting1
DB00563Methotrexate1Recruiting1
DB09035Nivolumab1Recruiting1
DB09073Palbociclib1Recruiting1
DB00059Pegaspargase1Recruiting1
DB12920Pinometostat1Completed1
DB00860Prednisolone1Recruiting1
DB06273Tocilizumab1Recruiting1
DB11678Treosulfan1Recruiting1
DB00541Vincristine1Recruiting1
DB00087Alemtuzumab1 / 2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)1 / 2Terminated1
DB00531Cyclophosphamide1 / 2Unknown Status1
DB00091Cyclosporine1 / 2Completed1
DB00987Cytarabine1 / 2Completed1
DB00987Cytarabine1 / 2Recruiting1
DB00099Filgrastim1 / 2Completed1
DB00099Filgrastim1 / 2Unknown Status1
DB01073Fludarabine1 / 2Completed1
DB01073Fludarabine1 / 2Terminated1
DB01073Fludarabine1 / 2Unknown Status1
DB01042Melphalan1 / 2Terminated2
DB00688Mycophenolate mofetil1 / 2Unknown Status1
DB00039Palifermin1 / 2Recruiting1
DB00073Rituximab1 / 2Completed1
DB00073Rituximab1 / 2Recruiting1
DB00073Rituximab1 / 2Unknown Status1
DB00864Tacrolimus1 / 2Completed1
DB00864Tacrolimus1 / 2Unknown Status1
DB04572Thiotepa1 / 2Terminated2
DB09312Antilymphocyte immunoglobulin (horse)2Active Not Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)2Terminated1
DB00098Antithymocyte immunoglobulin (rabbit)2Active Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Terminated1
DB00188Bortezomib2Completed1
DB00188Bortezomib2Terminated1
DB01008Busulfan2Active Not Recruiting1
DB01008Busulfan2Completed1
DB01008Busulfan2Recruiting4
DB00631Clofarabine2Active Not Recruiting1
DB06189Clofarabine2Active Not Recruiting1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Not Yet Recruiting1
DB00531Cyclophosphamide2Recruiting4
DB00091Cyclosporine2Completed1
DB00091Cyclosporine2Not Yet Recruiting1
DB00091Cyclosporine2Recruiting1
DB00987Cytarabine2Completed1
DB00987Cytarabine2Recruiting1
DB00694Daunorubicin2Completed1
DB06210Eltrombopag2Completed1
DB00099Filgrastim2Active Not Recruiting1
DB00099Filgrastim2Recruiting1
DB15223Flotetuzumab2Not Yet Recruiting1
DB01073Fludarabine2Active Not Recruiting1
DB01073Fludarabine2Completed1
DB01073Fludarabine2Not Yet Recruiting1
DB01073Fludarabine2Recruiting5
DB01073Fludarabine2Unknown Status1
DB09570Ixazomib2Active Not Recruiting1
DB00160L-Alanine2Active Not Recruiting1
DB04835Maraviroc2Completed1
DB00888Mechlorethamine2Active Not Recruiting1
DB01042Melphalan2Active Not Recruiting1
DB01042Melphalan2Recruiting1
DB00563Methotrexate2Completed1
DB00563Methotrexate2Recruiting1
DB01141Micafungin2Completed1
DB00688Mycophenolate mofetil2Active Not Recruiting1
DB00688Mycophenolate mofetil2Completed2
DB00688Mycophenolate mofetil2Recruiting3
DB00039Palifermin2Withdrawn1
DB00811Ribavirin2Active Not Recruiting1
DB00073Rituximab2Active Not Recruiting1
DB13647Semustine2Recruiting1
DB00877Sirolimus2Recruiting1
DB09143Sonidegib2Completed1
DB00864Tacrolimus2Active Not Recruiting1
DB00864Tacrolimus2Completed1
DB00864Tacrolimus2Recruiting2
DB00864Tacrolimus2Terminated1
DB04572Thiotepa2Recruiting2
DB06273Tocilizumab2Recruiting1
DB11678Treosulfan2Recruiting1
DB06334Tucidinostat2Not Yet Recruiting1
DB00631Clofarabine2 / 3Completed1
DB00531Cyclophosphamide2 / 3Completed1
DB00531Cyclophosphamide2 / 3Recruiting2
DB00987Cytarabine2 / 3Recruiting2
DB01254Dasatinib2 / 3Recruiting1
DB01234Dexamethasone2 / 3Recruiting2
DB00997Doxorubicin2 / 3Recruiting2
DB00773Etoposide2 / 3Completed1
DB00773Etoposide2 / 3Recruiting2
DB01177Idarubicin2 / 3Recruiting2
DB01033Mercaptopurine2 / 3Recruiting2
DB00563Methotrexate2 / 3Recruiting2
DB00059Pegaspargase2 / 3Recruiting2
DB06334Tucidinostat2 / 3Recruiting3
DB00541Vincristine2 / 3Recruiting2
DB00531Cyclophosphamide3Active Not Recruiting1
DB00531Cyclophosphamide3Recruiting1
DB00563Methotrexate3Active Not Recruiting1
DB00563Methotrexate3Recruiting1
DB00688Mycophenolate mofetil3Recruiting1
DB00864Tacrolimus3Active Not Recruiting1
DB00864Tacrolimus3Recruiting1
DB01008Busulfan4Not Yet Recruiting1
DB00531Cyclophosphamide4Not Yet Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB01008BusulfanNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableTerminated1
DB00091CyclosporineNot AvailableRecruiting1
DB01073FludarabineNot AvailableCompleted1
DB01073FludarabineNot AvailableTerminated2
DB01042MelphalanNot AvailableCompleted1
DB01042MelphalanNot AvailableTerminated1
DB00563MethotrexateNot AvailableRecruiting1
DB00688Mycophenolate mofetilNot AvailableRecruiting1
DB04572ThiotepaNot AvailableTerminated1