Hemodialysis-dependent chronic kidney disease (HDD-CKD)

Also known as: Chronic Kidney Disease, Stage 5 / Stage 5 Chronic Kidney Disease / Stage 5 Chronic Kidney Diseases / Chronic Kidney Disease - Stage V / Chronic Kidney Disease, Stage V / Stage V Chronic Kidney Disease / Chronic Kidney Disease Stage V / Dialysis-dependent Chronic Kidney Disease / Hemodialysis-dependent chronic kidney disease / Chronic Kidney Diseases Stage 5 / Chronic Kidney Disease Stage 5 / Chronic kidney disease, Dialysis / CKD stage 5 / Chronic kidney disease / Chronic Kidney Diseases

DrugDrug NameDrug Description
DB06410DoxercalciferolDoxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. Doxercalciferol is marketed under the brand name Hectoral by Genzyme Corporation, and is manufactured by Catalent Pharma Solutions, Inc.
DB09147Ferric pyrophosphateFerric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate.[A31979] It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability.[L1433]
DB09146Iron saccharateIron saccharate (Sucroferric oxyhydroxide or Iron Sucrose) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron saccharate is more preferred in chronic kidney disease patients.
DB00910ParicalcitolParicalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.